Results 61 to 70 of about 955,520 (208)

Effects of Aging on Glucose and Lipid Metabolism in Mice

Aging Cell, Volume 24, Issue 4, April 2025.
Lien et al. report a characterization of metabolism with aging across three different strains of mice. They find that glucose metabolism is robust during healthy aging; however, aging tissues exhibit evidence of upregulated fatty acid and sphingolipid metabolism reactions that regenerate NAD+ from NADH.
Evan C. Lien, Ngoc Vu, Anna M. Westermark, Laura V. Danai, Allison N. Lau, Yetiş Gültekin, Matthew A. Kukurugya, Bryson D. Bennett, Matthew G. Vander Heiden   +8 more
wiley   +1 more source

Optimization of 1H‐MRS methods for large‐volume acquisition of low‐concentration downfield resonances at 3 T and 7 T

Magnetic Resonance in Medicine, Volume 93, Issue 1, Page 18-30, January 2025.
Abstract Purpose This goal of this study was to optimize spectrally selective 1H‐MRS methods for large‐volume acquisition of low‐concentration metabolites with downfield resonances at 7 T and 3 T, with particular attention paid to detection of nicotinamide adenine dinucleotide (NAD+) and tryptophan.
Neil E. Wilson, Mark A. Elliott, Ravi Prakash Reddy Nanga, Sophia Swago, Walter R. Witschey, Ravinder Reddy   +5 more
wiley   +1 more source

Сравнительный анализ технологических схем измельчения руд меди на польском предприятии KGHM POLSKA MIEDŹ S.A. [PDF]

, 2012
Приведено огляд технологічних схем подрібнення мідних руд на підприємтсві KGHM POLSKA MIEDŹ S.A. (Польща) та їх порівняльний аналіз.Приведен обзор технологических схем измельчения медных руд на предприятии KGHM POLSKA MIEDŹ S.A.
Nad, Alona, Надь, Алена
core  

Torque and temperature dependence of the hysteretic voltage-induced torsional strain in tantalum trisulfide

, 2011
We have measured the dependence of the hysteretic voltage-induced torsional strain (VITS) in crystals of orthorhombic tantalum trisulfide on temperature and applied torque.
F. Ya. Nad’, H. Zhang, J. Nichols, J. W. Brill   +3 more
core   +1 more source

Global economy knows no borders [PDF]

, 2015
Artykuł naukowy „Global economy knows no borders” jest podsumowaniem wystąpienia profesora Marka Belki podczas konferencji naukowej “2014 – New Opportunities for Japan – V-4 Cooperation” zorganizowanej przez Wydział Socjologiczno-Ekonomiczny Uniwersytetu
Belka, Marek
core   +1 more source

Effect of Dietary Ketosis and Nicotinamide Riboside on Hippocampal Krebs Cycle Intermediates and Mitochondrial Energetics in a DNA Repair‐Deficient 3xTg/POLβ+/− Alzheimer Disease Mouse Model

Journal of Neurochemistry, Volume 169, Issue 1, January 2025.
Alzheimer disease causes neurodegeneration of the hippocampus. It impedes brain glucose metabolism and impairs mitochondrial energy along electron transport chain (ETC). Will a ketone‐based diet with nicotinamide riboside restore hippocampal energy in an Alzheimer mouse model?
Robert Pawlosky, Tyler G. Demarest, M. Todd King, Darlene Estrada, Richard L. Veech, Vilhelm A. Bohr   +5 more
wiley   +1 more source

Sava Savanović: el primer vampiro serbio y los muertos vivientes de los Balcanes

Balajú, 2016
Este artículo se presenta una breve exposición de las tradiciones culturales en torno a los vampiros en las zonas de Serbia, Ucrania y la Transilvania medieval.
Jelena Nađ
doaj   +1 more source

Analysis of ligation and DNA binding by Escherichia coli DNA ligase (LigA). [PDF]

, 2005
NAD+-dependent DNA ligases are essential enzymes in bacteria, with the most widely studied of this class of enzymes being LigA from Escherichia coli. NAD+-dependent DNA ligases comprise several discrete structural domains, including a BRCT domain at the ...
Adam Wilkinson, Alexandra Bonner, Altschul, Andrew Hemmings, Andrew Smith, Baer, Bork, Brotz-Oesterhelt, Callebaut, Derbyshire, Dermody, Desmond Bullard, Doherty, Doherty, Doherty, Feng, Gajiwala, Georlette, Georlette, Glover, Gong, Grawunder, Guex, Gunther, Halligan, Heather Sayer, Herrmann, Huyton, Jeon, Joo, Kaczmarek, Kodama, Krishnan, Lavesa-Curto, Lee, Legrain, Lehman, Manuel Lavesa-Curto, Masson, Odell, Pascal, Richard Bowater, Sambrook, Shuman, Singleton, Sriskanda, Sriskanda, Sriskanda, Sriskanda, Subramanya, Timson, Timson, Wieland, Wilkinson, Wilkinson, Williams, Yamane, Yamane, Zhang, Zimmerman   +59 more
core   +1 more source

Dual treatment with kynurenine pathway inhibitors and NAD+ precursors synergistically extends life span in Drosophila

Aging Cell, Volume 23, Issue 4, April 2024.
Our study explores the impact of kynurenine pathway (KP) modulation and NAD+ supplementation on aging Drosophila. We found that KP inhibition combined with NAD+ precursors significantly enhances physical performance and extends life span. These findings suggest that targeted interventions in KP and NAD+ metabolism can synergistically improve health ...
Mariann M. Gabrawy, Reyhan Westbrook, Austin King, Nick Khosravian, Neeraj Ochaney, Tagide DeCarvalho, Qinchuan Wang, Yuqiong Yu, Qiao Huang, Adam Said, Michael Abadir, Cissy Zhang, Pratik Khare, Jennifer E. Fairman, Anne Le, Ginger L. Milne, Fernando J. Vonhoff, Jeremy D. Walston, Peter M. Abadir   +18 more
wiley   +1 more source

A ribose-functionalized NAD+ with unexpected high activity and selectivity for protein poly-ADP-ribosylation. [PDF]

, 2019
Nicotinamide adenine dinucleotide (NAD+)-dependent ADP-ribosylation plays important roles in physiology and pathophysiology. It has been challenging to study this key type of enzymatic post-translational modification in particular for protein poly-ADP ...
Chen, Jingwen, Cheng, Qinqin, Dai, Zhefu, Evdokimov, Nikolai M, Lam, Albert T, Louie, Stan G, Lu, Yanran, Pei, Hua, Zhang, Xiao-Nan, Zhang, Yong   +9 more
core   +1 more source