Results 91 to 100 of about 2,049 (165)

Escaping death: Mitochondrial redox homeostasis in cancer cells [PDF]

, 2017
Reactive oxygen species (ROS) are important signaling molecules that act through the oxidation of nucleic acids, proteins, and lipids. Several hallmarks of cancer, including uncontrolled proliferation, angiogenesis, and genomic instability, are promoted ...
Ciccarese, Francesco, Ciminale, Vincenzo
core   +1 more source

Phytomelatonin: From Intracellular Signaling to Global Horticulture Market

Journal of Pineal Research, Volume 76, Issue 5, August 2024.
ABSTRACT Melatonin (N‐acetyl‐5‐methoxytryptamine), a well‐known mammalian hormone, has been having a great relevance in the Plant World in recent years. Many of its physiological actions in plants are leading to possible features of agronomic interest, especially those related to improvements in tolerance to stressors and in the postharvest life of ...
Morteza Soleimani Aghdam, Marino B. Arnao   +1 more
wiley   +1 more source

An Exome-wide Association Study for Type 2 Diabetes–Attributed End-Stage Kidney Disease in African Americans

Kidney International Reports, 2018
Introduction: Compared with European Americans, African Americans (AAs) are at higher risk for developing end-stage kidney disease (ESKD). Genome-wide association studies (GWAS) have identified >70 genetic variants associated with kidney function and ...
Meijian Guan, Jacob M. Keaton, Latchezar Dimitrov, Pamela J. Hicks, Jianzhao Xu, Nicholette D. Palmer, James G. Wilson, Barry I. Freedman, Donald W. Bowden, Maggie C.Y. Ng   +9 more
doaj   +1 more source

Remarks on nomenclature of Triassic carbonate rocks from the Tatra Mts. [PDF]

, 2010
The Upper Olenekian and Middle Triassic shallow water carbonates from Tatra Mts. were hitherto described using old, descriptive nomenclature only. Moreover, some sedimentological features were also misinterpreted, for example, fenestral structures were ...
Jaglarz, Piotr, Rychliński, Tomasz
core  

Detailed DNA methylation characterisation of phyllodes tumours identifies a signature of malignancy and distinguishes phyllodes from metaplastic breast carcinoma

The Journal of Pathology, Volume 262, Issue 4, Page 480-494, April 2024.
Abstract Phyllodes tumours (PTs) are rare fibroepithelial lesions of the breast that are classified as benign, borderline, or malignant. As little is known about the molecular underpinnings of PTs, current diagnosis relies on histological examination. However, accurate classification is often difficult, particularly for distinguishing borderline from ...
Braydon Meyer, Clare Stirzaker, Sonny Ramkomuth, Kate Harvey, Belinda Chan, Cheok Soon Lee, Rooshdiya Karim, Niantao Deng, Kelly A Avery‐Kiejda, Rodney J Scott, Sunil Lakhani, Stephen Fox, Elizabeth Robbins, Joo‐Shik Shin, Jane Beith, Anthony Gill, Loretta Sioson, Charles Chan, Mrudula Krishnaswamy, Caroline Cooper, Sanjay Warrier, Cindy Mak, John EJ Rasko, Charles G Bailey, Alexander Swarbrick, Susan J Clark, Sandra O'Toole, Ruth Pidsley   +27 more
wiley   +1 more source

G‐protein‐coupled estrogen receptor 1 promotes peritoneal metastasis of gastric cancer through nicotinamide adenine dinucleotide kinase 1‐mediated redox modulation

The FASEB Journal, Volume 38, Issue 3, 15 February 2024.
Proposed mechanism of GPER1 action in the metastatic dissemination of GC cells. GPER1 was able to maintain redox homeostasis in gastric cancer cells when separated from extracellular matrix and promote anoikis resistance and distance metastasis by regulating the expression and activity of NADK1. Abstract Adipose tissue is the second most important site
Teng Wu, Ke Ding, Chun Wang, Guoliang Lin, Chengjie Xie, Xianying Chen, Quanxin Li, Fenghai Yu, Yuling Mao, Wei Hong, Lei Lu, Shuai Li   +11 more
wiley   +1 more source

Enhanced isopropanol–butanol–ethanol mixture production through manipulation of intracellular NAD(P)H level in the recombinant Clostridium acetobutylicum XY16

Biotechnology for Biofuels, 2018
Background The formation of by-products, mainly acetone in acetone–butanol–ethanol (ABE) fermentation, significantly affects the solvent yield and downstream separation process.
Chao Wang, Fengxue Xin, Xiangping Kong, Jie Zhao, Weiliang Dong, Wenming Zhang, Jiangfeng Ma, Hao Wu, Min Jiang   +8 more
doaj   +1 more source

Homeostatic regulation of NAD(H) and NADP(H) in cells

Genes and Diseases
Nicotinamide adenine dinucleotide (NAD+)/reduced NAD+ (NADH) and nicotinamide adenine dinucleotide phosphate (NADP+)/reduced NADP+ (NADPH) are essential metabolites involved in multiple metabolic pathways and cellular processes.
Luojun Chen, Xiaoke Xing, Pingfeng Zhang, Lulu Chen, Huadong Pei   +4 more
doaj   +1 more source

NADK is activated by oncogenic signaling to sustain pancreatic ductal adenocarcinoma. Schild et al.

, 2021
Tanya Schild
openalex   +1 more source

Stronger inflammatory/cytotoxic T cell response in women identified by microarray analysis [PDF]

, 2008
Women develop chronic inflammatory autoimmune diseases like lupus more often than men. The mechanisms causing the increased susceptibility are incompletely understood, although estrogen is believed to contribute.
Anura Hewagama, Bruce C. Richardson, Dipak Patel, Faith M. Strickland, Sushma Yarlagadda   +4 more
core   +1 more source