Results 41 to 50 of about 2,049 (165)

Supplementary Table 11 from NUAK1-Mediated Phosphorylation of NADK Mitigates ROS Accumulation to Promote Osimertinib Resistance in Non–Small Cell Lung Carcinoma

open access: gold
<p>Supplementary Table 11 Detection of SNVs and CNVs in HCC827OR and PC9OR</p>
Wei Lin   +9 more
openalex   +2 more sources

Separating NADH and NADPH fluorescence in live cells and tissues using FLIM [PDF]

open access: yes, 2014
NAD is a key determinant of cellular energy metabolism. In contrast, its phosphorylated form, NADP, plays a central role in biosynthetic pathways and antioxidant defence.
Bain, Angus J.   +6 more
core   +3 more sources

Multiplex protein profiling of bronchial aspirates reveals disease-, mortality- and respiratory sequelae-associated signatures in critically ill patients with ARDS secondary to SARS-CoV-2 infection

open access: yesFrontiers in Immunology, 2022
IntroductionBronchial aspirates (BAS) obtained during invasive mechanical ventilation (IMV) constitutes a useful tool for molecular phenotyping and decision making.AimTo identify the proteomic determinants associated with disease pathogenesis, all-cause ...
Marta Molinero   +48 more
doaj   +1 more source

Mitochondrial NAD kinase in health and disease

open access: yesRedox Biology, 2023
Nicotinamide adenine dinucleotide phosphate (NADP), a co-enzyme and an electron carrier, plays crucial roles in numerous biological functions, including cellular metabolism and antioxidation.
Ren Zhang, Kezhong Zhang
doaj   +1 more source

The Pseudogenes of Barley [PDF]

open access: yes, 2017
Pseudogenes have a reputation of being ‘evolutionary relics’ or ‘junk DNA’. While they are well characterized in mammals, studies in more complex plant genomes were so far hampered by the absence of reference genome sequences.
Altschul   +53 more
core   +2 more sources

Inducing disulfidptosis in tumors:potential pathways and significance. [PDF]

open access: yesMedComm (2020)
Exploring the mechanisms of disulfidptosis reveals potential pathways to induce tumor cell death. Tumor cells with high SLC7A11 expression uptake a large amount of cystine to meet their metabolic needs. The reduction of cystine requires the involvement of the Trx system and NADPH.
Mi T, Kong X, Chen M, Guo P, He D.
europepmc   +2 more sources

Genome-wide analysis of gene expression during Xenopus tropicalis tadpole tail regeneration [PDF]

open access: yes, 2011
BACKGROUND: The molecular mechanisms governing vertebrate appendage regeneration remain poorly understood. Uncovering these mechanisms may lead to novel therapies aimed at alleviating human disfigurement and visible loss of function following injury ...
Boyan Bonev   +9 more
core   +2 more sources

Fractionation of Hydrogen Isotopes by Sulfate- and Nitrate-Reducing Bacteria. [PDF]

open access: yes, 2016
Hydrogen atoms from water and food are incorporated into biomass during cellular metabolism and biosynthesis, fractionating the isotopes of hydrogen-protium and deuterium-that are recorded in biomolecules.
Dawson, Katherine S   +3 more
core   +5 more sources

Cloning, Expression and Characterization of NAD Kinase from Staphylococcus aureus Involved in the Formation of NADP (H): A Key Molecule in the Maintaining of Redox Status and Biofilm Formation

open access: yesAdvanced Biomedical Research, 2017
Background:Staphylococcus aureus has the ability to form biofilms on any niches, a key pathogenic factor of this organism and this phenomenon is directly related to the concentration of NADPH.
U Venkateswara Prasad   +7 more
doaj   +1 more source

Distinct dual roles of p-Tyr42 RhoA GTPase in tau phosphorylation and ATP citrate lyase activation upon different Aβ concentrations

open access: yesRedox Biology, 2020
Both the accumulation of Amyloid-β (Aβ) in plaques and phosphorylation of Tau protein (p-Tau) in neurofibrillary tangles have been identified as two major symptomatic features of Alzheimer's disease (AD).
Kim Cuong Cap   +11 more
doaj   +1 more source

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