Results 51 to 60 of about 2,008 (163)

Evaluation and Characterization of Post-Stroke Lung Damage in a Murine Model of Cerebral Ischemia [PDF]

, 2022
After stroke and other brain injuries, there is a high incidence of respiratory complications such as pneumonia or acute lung injury. The molecular mechanisms that drive the brain-lung interaction post-stroke have not yet been elucidated.
Bustamante, Alejandro, Faura, Júlia, Gasull Dalmau, Teresa, Ma, Feifei, Montaner, Joan, Penalba, Anna, Ramiro, Laura, Rosell Novel, Anna, Simats Oriol, Alba, Universitat Autònoma de Barcelona   +9 more
core   +1 more source

NAD Kinases: Metabolic Targets Controlling Redox Co-enzymes and Reducing Power Partitioning in Plant Stress and Development

Frontiers in Plant Science, 2018
NAD(H) and NADP(H) are essential co-enzymes which dominantly control a number of fundamental biological processes by acting as reducing power and maintaining the intracellular redox balance of all life kingdoms.
Bin-Bin Li, Xiang Wang, Li Tai, Tian-Tian Ma, Abdullah Shalmani, Wen-Ting Liu, Wen-Qiang Li, Kun-Ming Chen   +7 more
doaj   +1 more source

Differential expression of NADK in cancer of the skin: malignant melanoma.

, 2023
Skin cancer is diagnosed in nearly 1.5 million patients each year (1). While patients with basal and squamous cell carcinomas are provided with 5-year survival rates at nearly 100% and 90%, respectively, patients diagnosed with cutaneous melanoma (metastatic melanoma) are provided 5-year survival rates at 91.4% at stage I and 24.6% at stage IV (2-5 ...
openaire   +1 more source

Enhancing β-Carotene Production in Escherichia coli by Perturbing Central Carbon Metabolism and Improving the NADPH Supply

Frontiers in Bioengineering and Biotechnology, 2020
Beta (β)-carotene (C40H56; a provitamin) is a particularly important carotenoid for human health. Many studies have focused on engineering Escherichia coli as an efficient heterologous producer of β-carotene.
Yuanqing Wu, Yuanqing Wu, Panpan Yan, Panpan Yan, Yang Li, Yang Li, Yang Li, Xuewei Liu, Xuewei Liu, Zhiwen Wang, Zhiwen Wang, Tao Chen, Tao Chen, Xueming Zhao, Xueming Zhao   +14 more
doaj   +1 more source

Modeling and simulation of the main metabolism in Escherichia coli and its several single-gene knockout mutants with experimental verification [PDF]

, 2010
Background: It is quite important to simulate the metabolic changes of a cell in response to the change in culture environment and/or specific gene knockouts particularly for the purpose of application in industry.
Kadir, Tuty Asmawaty Abdul, Kierzek, Andrzej M., Mannan, Ahmad A., McFadden, Johnjoe, Shimizu, Kazuyuki   +4 more
core   +4 more sources

Issues concerning the waterfall of hybrid inflation

, 2011
We discuss the waterfall that ends hybrid inflation. Making some simplifying assumptions, that may be satisfied by GUT inflation models, two issues are addressed.
Lyth, David H.
core   +1 more source

ModuLand plug-in for Cytoscape: determination of hierarchical layers of overlapping network modules and community centrality [PDF]

, 2012
Summary: The ModuLand plug-in provides Cytoscape users an algorithm for determining extensively overlapping network modules. Moreover, it identifies several hierarchical layers of modules, where meta-nodes of the higher hierarchical layer represent ...
Adamcsek, Ahn, Bader, Balázs Papp, Balázs Szappanos, Fortunato, Ghosh, Ghosh, Guimera, István A. Kovács, Kovács, Kreimer, Mihalik, Morris, Máté Szalay-Bekő, Palla, Parter, Pál, Péter Csermely, Rhrissorrakrai, Rivera, Robin Palotai, Samal, Sethi, Shannon, Su, Tamames   +26 more
core   +6 more sources

Metabolic Dependencies in Pancreatic Cancer. [PDF]

, 2018
Pancreatic ductal adenocarcinoma (PDA) is a highly lethal cancer with a long-term survival rate under 10%. Available cytotoxic chemotherapies have significant side effects, and only marginal therapeutic efficacy. FDA approved drugs currently used against
Brody, Jonathan R., Vaziri-Gohar, Ali, Winter, Jordan M., Zarei, Mahsa   +3 more
core   +1 more source

Single‐Cell Hyperthermia: Diamond Quantum Thermometry Reveals Thermal Control of Macrophage Polarization

Advanced Materials, Volume 38, Issue 8, 6 February 2026.
Photothermal nanodiamonds with quantum sensing capabilities generate lysosome‐confined hyperthermia, enabling simultaneous temperature and radical detection via diamond sensing. This localized thermal and oxidative stress drives pro‐inflammatory (M1) macrophage polarization, revealing a new strategy for precision immunomodulation through subcellular ...
Kaiqi Wu, Qi Lu, Yong Ren, Priyadharshini Balasubramanian, Kazem Ebadi Jalal, Hannah Klug, Matthias Klein, Toszka Bohn, Tobias Bopp, Fedor Jelezko, Yingke Wu, Tanja Weil   +11 more
wiley   +1 more source

Extramedullary relapse of multiple myeloma defined as the highest risk group based on deregulated gene expression data

Biomedical Papers, 2015
Background: Multiple myeloma (MM) is characterized by malignant proliferation of plasma cells (PC) which accumulate in the bone marrow (BM). The advent of new drugs has changed the course of the disease from incurable to treatable, but most patients ...
Sabina Sevcikova, Helena Paszekova, Lenka Besse, Lenka Sedlarikova, Veronika Kubaczkova, Martina Almasi, Ludek Pour, Roman Hajek   +7 more
doaj   +1 more source