Results 71 to 80 of about 2,008 (163)
Arabidopsis peroxisome proteomics [PDF]
, 2013 The analytical depth of investigation of the peroxisomal proteome of the model plant Arabidopsis thaliana has not yet reached that of other major cellular organelles such as chloroplasts or mitochondria.
Behrens, Christof +3 more
core +3 more sources
Advanced Science, Volume 12, Issue 19, May 22, 2025.LACK156‐173 is internalized into RA‐FLSs via CAPN2‐mediated endocytosis and inhibits the aggressive phenotype of RA‐FLSs by restoring dysregulated fatty acid synthesis metabolism mediated by overexpressed FASN. The findings suggest that targeting the restoration of fatty acid metabolism could potentially alleviate synovial invasion and joint damage in ...
Jianling Su +17 more
wiley +1 more source
浙江大学学报. 农业与生命科学版, 2020 Enzymatic browning is one of the main factors affecting the quality and shelf life of fresh-cut lotus root. The present study aimed to investigate the mechanism of inhibition of elevated carbon dioxide (CO2) on enzymatic browning by applying 20% CO2 to ...
LI Dong +7 more
doaj +1 more source
The regulation of ferroptosis by MESH1 through the activation of the integrative stress response
Cell Death and Disease, 2021 All organisms exposed to metabolic and environmental stresses have developed various stress adaptive strategies to maintain homeostasis. The main bacterial stress survival mechanism is the stringent response triggered by the accumulation “alarmone” (p ...
Chao-Chieh Lin +6 more
doaj +1 more source
Suspended sediment load and mechanical erosion in the Senegal basin : estimation of the surface runoff concentration and relative contributions of channel and slope erosion [PDF]
, 1987 Cette étude a pour but de mieux cerner les mécanismes d'acquisition de la charge solide et de l'évolution de l'érosion dans le bassin du fleuve Sénégal de 1979 à 1984.
Gac, Jean-Yves, Kattan, Z., Probst, J.L.
core +1 more source
Serum Proteomic and Metabolomic Signatures of High Versus Low Physical Function in Octogenarians
Aging Cell, Volume 24, Issue 5, May 2025.Circulating factors are strongly implicated in modulating biological aging. In this study we show that the serum proteomic and metabolomic profile of high functioning octogenarians suggests lower activation of SASP, preservation of the tryptophan‐kynurenic pathway, higher lipophosphatidyl cholines promoting mitochondrial function, and reduced ...
Ceereena Ubaida‐Mohien +11 more
wiley +1 more source
Blood, 2018 Abstract Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer with a cumulative risk of ~1 in 2,000 children by the age of 15 years and an increasing incidence over the last 30 years.Whilst advances in the use of combination chemotherapy have significantly improved outcomes, current treatments remain toxic and can have ...
De Braekeleer, E. +10 more
openaire +2 more sources
Production of 2,3-butanediol in Saccharomyces cerevisiae by in silico aided metabolic engineering [PDF]
, 2012 BACKGROUND: 2,3-Butanediol is a chemical compound of increasing interest due to its wide applications. It can be synthesized via mixed acid fermentation of pathogenic bacteria such as Enterobacter aerogenes and Klebsiella oxytoca.
Chiam Yu Ng +3 more
core +1 more source
Advanced Science, Volume 12, Issue 9, March 6, 2025.The functions of most phosphorylation sites remain unknown, which is the “bottleneck” of phosphorylation modification studies. Here, a state‐of‐the‐art method, MMFuncPhos, is developed to predict functional phosphorylation sites based on a multi‐modal deep learning framework.
Juan Xie +5 more
wiley +1 more source
Journal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 1, February 2025.ABSTRACT Background Sarcopenia severely affects the physical health of the elderly. Currently, there is no specific drug available for sarcopenia. This study aims to identify pathogenic proteins and druggable targets for sarcopenia through Mendelian randomization (MR)–based analytical framework.
Simin Wen +11 more
wiley +1 more source