Results 1 to 10 of about 182,746 (311)
Elevating cytosolic NADPH metabolism in endothelial cells ameliorates vascular aging [PDF]
Nature CommunicationsReduced nicotinamide adenine dinucleotide phosphate (NADPH) metabolism is independently regulated in different compartments in endothelial cells (EC). The metabolic profile and functional impact of NADPH during EC senescence remain largely unknown. Using
Dan Wu +10 more
doaj +2 more sources
NADPH alleviates LPS-induced neuropathology and depression-like behaviors by suppressing microglial inflammatory response [PDF]
Translational PsychiatryOur study investigated the role of nicotinamide adenine dinucleotide phosphate (NADPH) in neuroinflammation-associated depression-like behaviors. Using a lipopolysaccharide (LPS)-induced mouse model of depression, we found that NADPH significantly ...
Dian He +8 more
doaj +2 more sources
Separating NADH and NADPH fluorescence in live cells and tissues using FLIM [PDF]
Nature Communications, 2014 Thomas S Blacker +2 more
exaly +2 more sources
Glucose as a Major Antioxidant: When, What for and Why It Fails?
Antioxidants, 2020 A human organism depends on stable glucose blood levels in order to maintain its metabolic needs. Glucose is considered to be the most important energy source, and glycolysis is postulated as a backbone pathway.
Andriy Cherkas +4 more
doaj +1 more source
Frontiers in Bioscience-Landmark, 2022 Fatty acid metabolism has attracted extensive attention for its key role in the occurrence and development of tumors. Fatty acids not only participate in the biosynthesis of phospholipids in the membrane to overcome the demand for rapidly proliferating ...
Hongdan Chen +5 more
doaj +1 more source
The Possibility of Destruction of Cellular NADPH in the Presence of Free Fe(II) Ion, Arsine, and Other Hazardous Species [PDF]
Research in Molecular Medicine, 2022 Background: As the nicotinamide adenine dinucleotide phosphate (NADPH) is the key natural electron generator of the alive cells, investigation of the possibility of inactivation or even destruction of it by hazardous chemical molecules or ions seems to ...
Seyyed Amir Siadati +2 more
doaj
Biomolecular Concepts, 2022 Systemic sclerosis (SSc) is an immune disorder characterized by diffuse fibrosis and vascular abnormalities of the affected organs. Although the etiopathology of this disease is largely unknown, endothelial damage and oxidative stress appear implicated ...
Posadino Anna Maria +7 more
doaj +1 more source
Redox Report, 2021 Objectives The study explores the protective role of the peripheral serum of limb remote ischemic postconditioning (LRIP) in reducing the reactive oxygen species (ROS) levels and neutrophil activation, which are responsible for the deleterious ...
Gangling Chen +7 more
doaj +1 more source
Metabolites, 2019 NADPH is the primary source of cellular reductant for biosynthesis, and strategies for increasing productivity via metabolic engineering need to take account of the requirement for reducing power.
Edward N. Smith +3 more
doaj +1 more source
Biosynthesis of food constituents: Vitamins. 2. Water-soluble vitamins: Part 1 - a review
Czech Journal of Food Sciences, 2007 This review article gives a survey of the generally accepted biosynthetic pathways that lead to water-soluble vitamins in microorganisms, plants and some animals.
Jan Velíšek, Karel Cejpek
doaj +1 more source