Results 11 to 20 of about 175,216 (165)

Increasing NADPH impairs fungal H2O2 resistance by perturbing transcriptional regulation of peroxiredoxin

Bioresources and Bioprocessing, 2022
NADPH provides the reducing power for decomposition of reactive oxygen species (ROS), making it an indispensable part during ROS defense. It remains uncertain, however, if living cells respond to the ROS challenge with an elevated intracellular NADPH ...
Jingyi Li, Yanwei Sun, Feiyun Liu, Yao Zhou, Yunfeng Yan, Zhemin Zhou, Ping Wang, Shengmin Zhou   +7 more
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Limitations of Deuterium-Labelled Substrates for Quantifying NADPH Metabolism in Heterotrophic Arabidopsis Cell Cultures

Metabolites, 2019
NADPH is the primary source of cellular reductant for biosynthesis, and strategies for increasing productivity via metabolic engineering need to take account of the requirement for reducing power.
Edward N. Smith, James S. O. McCullagh, R. George Ratcliffe, Nicholas J. Kruger   +3 more
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The Crosstalk Between Cancer Cells and Neutrophils Enhances Hepatocellular Carcinoma Metastasis via Neutrophil Extracellular Traps-Associated Cathepsin G Component: A Potential Therapeutic Target

Journal of Hepatocellular Carcinoma, 2021
Xiangqian Guan, Yuyan Lu, Heping Zhu, Shuqi Yu, Wenxiu Zhao, Xiaoqin Chi, Chengrong Xie, Zhenyu Yin Department of Hepatobiliary Surgery, Zhongshan Hospital, Xiamen University, Fujian Provincial Key Laboratory of Chronic Liver Disease and Hepatocellular ...
Guan X, Lu Y, Zhu H, Yu S, Zhao W, Chi X, Xie C, Yin Z   +7 more
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Biosynthesis of food constituents: Vitamins. 2. Water-soluble vitamins: Part 1 - a review

Czech Journal of Food Sciences, 2007
This review article gives a survey of the generally accepted biosynthetic pathways that lead to water-soluble vitamins in microorganisms, plants and some animals.
Jan Velíšek, Karel Cejpek
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Role of Nitric Oxide in the Remodelling of Extracellular Matrix in Myxomatous Mitral Valve Degeneration of Dogs and Pigs

Brazilian Journal of Veterinary Pathology, 2011
Myxomatous mitral valve degeneration (MMVD) or endocardiosis is a heart valve disease that occurs in many mammalian species, especially in humans, dogs and pigs. Nitric oxide (NO) plays an important role in the MMVD development.
Leonardo dos R. Corrêa, Mariana B. R. Faleiro, Marcela M. P. Rodrigues, Hidelbrando R. D. Amaral, José B. Gama Filho, Moema P. C. Matos, Renée L. Amorim, Veridiana M. B. D. de Moura   +7 more
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Elementary Flux Mode Analysis Revealed Cyclization Pathway as a Powerful Way for NADPH Regeneration of Central Carbon Metabolism. [PDF]

PLoS ONE, 2015
NADPH regeneration capacity is attracting growing research attention due to its important role in resisting oxidative stress. Besides, NADPH availability has been regarded as a limiting factor in production of industrially valuable compounds. The central
Bin Rui, Yin Yi, Tie Shen, Meijuan Zheng, Wenwei Zhou, Honglin Du, Yadong Fan, Yongkang Wang, Zhengdong Zhang, Shengsheng Xu, Zhijie Liu, Han Wen, Xiaoyao Xie   +12 more
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Assessment of Glucose-6-Phosphate Dehydrogenase Deficiency and Anaemia in Apparently Healthy Students in Gombe State University [PDF]

Global Journal of Environmental Science & Sustainability
Glucose-6-phosphate dehydrogenase (G6PD) is a key regulatory enzyme in the pentose phosphate pathway (PPP) which produces nicotiamide adenine dinucleotide phosphate (NADPH) to maintain an adequate reducing environment in cells and is especially important
Lazarus J. Goje, Abubakar M. Hammari, Fauziya J. Kamara, Adamu J. Abubakar, Adamu U. Bashir   +4 more
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The folate cycle is a new metabolic weakness of cancer

Molecular & Cellular Oncology, 2017
Cancer cells harness nutrients to support its rapid proliferation through metabolic reprogramming. Our report identified folate cycle as a metabolic target in hepatocellular carcinoma.
Derek Lee, Carmen Chak-Lui Wong
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STAMP2 Attenuates Cardiac Dysfunction and Insulin Resistance in Diabetic Cardiomyopathy via NMRAL1-Mediated NF-κB Inhibition in Type 2 Diabetic Rats

Diabetes, Metabolic Syndrome and Obesity, 2022
Zhan Gao,1,2 Yun Ti,1 Bin Lu,1 Fang-qiang Song,1,3 Lei Zhang,1 Bo-ang Hu,1 Jia-ying Xie,1 Wei Zhang,1 Lu Han,1,4 Ming Zhong1 1The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education, Chinese National Health ...
Gao Z, Ti Y, Lu B, Song F, Zhang L, Hu B, Xie J, Zhang W, Han L, Zhong M   +9 more
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Cytosolic ME1 integrated with mitochondrial IDH2 supports tumor growth and metastasis

Redox Biology, 2020
NADPH is a pivotal cofactor that maintains redox homeostasis and lipogenesis in cancer cells and interference with NADPH production is a promising approach for treating cancer.
Chang Shao, Wenjie Lu, Ye Du, Wenchao Yan, Qiuyu Bao, Yang Tian, Guangji Wang, Hui Ye, Haiping Hao   +8 more
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