Results 11 to 20 of about 239,596 (347)
NADPH Oxidases and Their Role in Atherosclerosis [PDF]
Biomedicines, 2020 The current view on atherosclerosis positions it as a multifactorial disorder that results from the interplay between lipid metabolism disturbances and inflammatory processes.
A. Poznyak +5 more
semanticscholar +5 more sources
NADPH oxidases: an overview from structure to innate immunity-associated pathologies
Cellular and Molecular Immunology, 2014 Arvind Panday +2 more
exaly +2 more sources
Oxidative Medicine and Cellular Longevity, 2021 NADPH oxidase as an important source of intracellular reactive oxygen species (ROS) has gained enormous importance over the years, and the detailed structures of all the isoenzymes of the NADPH oxidase family and their regulation have been well explored.
Upasana Ganguly +6 more
semanticscholar +1 more source
NADPH Oxidase and Neurodegeneration [PDF]
Current Neuropharmacology, 2012 NADPH oxidase (Nox) is a unique, multi-protein, electron transport system that produces large amounts of superoxide via the reduction of molecular oxygen. Nox-derived reactive oxygen species (ROS) are known to be involved in a variety of physiological processes, including host defense and signal transduction.
Marina S. Hernandes, Luiz R.G. Britto
openaire +2 more sources
Glucose as a Major Antioxidant: When, What for and Why It Fails?
Antioxidants, 2020 A human organism depends on stable glucose blood levels in order to maintain its metabolic needs. Glucose is considered to be the most important energy source, and glycolysis is postulated as a backbone pathway.
Andriy Cherkas +4 more
doaj +1 more source
Frontiers in Bioscience-Landmark, 2022 Fatty acid metabolism has attracted extensive attention for its key role in the occurrence and development of tumors. Fatty acids not only participate in the biosynthesis of phospholipids in the membrane to overcome the demand for rapidly proliferating ...
Hongdan Chen +5 more
doaj +1 more source
Serine catabolism generates liver NADPH and supports hepatic lipogenesis
Nature Metabolism, 2021 Carbohydrate can be converted into fat by de novo lipogenesis, a process upregulated in fatty liver disease. Chemically, de novo lipogenesis involves polymerization and reduction of acetyl-CoA, using NADPH as the electron donor.
Zhaoyue Zhang +8 more
semanticscholar +1 more source
The Possibility of Destruction of Cellular NADPH in the Presence of Free Fe(II) Ion, Arsine, and Other Hazardous Species [PDF]
Research in Molecular Medicine, 2022 Background: As the nicotinamide adenine dinucleotide phosphate (NADPH) is the key natural electron generator of the alive cells, investigation of the possibility of inactivation or even destruction of it by hazardous chemical molecules or ions seems to ...
Seyyed Amir Siadati +2 more
doaj
Biomolecular Concepts, 2022 Systemic sclerosis (SSc) is an immune disorder characterized by diffuse fibrosis and vascular abnormalities of the affected organs. Although the etiopathology of this disease is largely unknown, endothelial damage and oxidative stress appear implicated ...
Posadino Anna Maria +7 more
doaj +1 more source
Redox Report, 2021 Objectives The study explores the protective role of the peripheral serum of limb remote ischemic postconditioning (LRIP) in reducing the reactive oxygen species (ROS) levels and neutrophil activation, which are responsible for the deleterious ...
Gangling Chen +7 more
doaj +1 more source