Results 51 to 60 of about 175,216 (165)

Elevating cytosolic NADPH metabolism in endothelial cells ameliorates vascular aging

Nature Communications
Reduced nicotinamide adenine dinucleotide phosphate (NADPH) metabolism is independently regulated in different compartments in endothelial cells (EC). The metabolic profile and functional impact of NADPH during EC senescence remain largely unknown. Using
Dan Wu, Bo Tan, Zijie Cheng, Haoqi Li, Huimin Li, Yun Yin, Fenfen Ma, Tao Chen, Xin Dong, Wang Wang, Qingxun Hu   +10 more
doaj   +1 more source

NADPH‐related processes studied with a SoxR‐based biosensor in Escherichia coli

MicrobiologyOpen, 2019
NADPH plays a crucial role in cellular metabolism for biosynthesis and oxidative stress responses. We previously developed the genetically encoded NADPH biosensor pSenSox based on the transcriptional regulator SoxR of Escherichia coli, its target ...
Alina Spielmann, Meike Baumgart, Michael Bott   +2 more
doaj   +1 more source

Acute stimulation of glucose metabolism by H2O2 sustains the NADPH steady-state under oxidative stress

Redox Biology
Oxidative stress reprograms metabolic flux from glycolysis to the pentose phosphate pathway. Recently, it has been proposed that NADPH acts as a key molecule in pentose phosphate pathway regulation by exerting negative feedback through tonic inhibition ...
C. Aburto, I. Ruminot, A. San Martín
doaj   +1 more source

NOX4 exacerbates Parkinson’s disease pathology by promoting neuronal ferroptosis and neuroinflammation

Neural Regeneration Research
Parkinson’s disease is primarily caused by the loss of dopaminergic neurons in the substantia nigra compacta. Ferroptosis, a novel form of regulated cell death characterized by iron accumulation and lipid peroxidation, plays a vital role in the death of ...
Zhihao Lin, Changzhou Ying, Xiaoli Si, Naijia Xue, Yi Liu, Ran Zheng, Ying Chen, Jiali Pu, Baorong Zhang   +8 more
doaj   +1 more source

ROS Signaling and NADPH Oxidase in Red Algae

Antioxidants
We explore the diverse roles of reactive oxygen species (ROS) and NADPH oxidases in red algae, focusing on their involvement in fertilization, wound repair, stress adaptation, and development.
Gwang-Hoon Kim, Eunyoung Shim, Giuseppe C. Zuccarello   +2 more
doaj   +1 more source

A Genetic Screen To Identify Genes Influencing the Secondary Redox Couple NADPH/NADP+ in the Yeast Saccharomyces cerevisiae

G3: Genes, Genomes, Genetics, 2020
Shambhu Yadav, Tejasvinee Atul Mody, Archi Sharma, Anand Kumar Bachhawat   +3 more
doaj   +1 more source

S10.6 The NADPH binding on phagocyte NADPH oxidase

Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2008
Baciou, Laura, Bizouarn, Tania
openaire   +1 more source

NADPH oxidase of neutrophils

Biochimica et Biophysica Acta (BBA) - Bioenergetics, 1996
Henderson, Lydia M., Chappell, J.Brian
openaire   +2 more sources

NADPH oxydase [PDF]

médecine/sciences, 2016
Magali Dupont, Alice Ouachée, Juliette Royer, Corinne Dupuy   +3 more
openaire   +1 more source

Mitochondrial NADK2-dependent NADPH controls tau oligomer uptake in human neurons. [PDF]

Alzheimers Dement
Pardo E, Kim T, Wallrabe H, Zengeler KE, Sagar VK, Mingledorff G, Sun X, Periasamy A, Lukens JR, Bloom GS, Norambuena A.   +10 more
europepmc   +1 more source