Results 21 to 30 of about 85,856,906 (279)
Modulation of Radiation-Induced NADPH Oxidases in Rat’s Heart Tissues by Melatonin [PDF]
Journal of Biomedical Physics and Engineering, 2021 Background: Experimental studies have shown that infiltration of inflammatory cells as well as upregulation of some cytokines play a central role in the development of late effects of ionizing radiation in heart tissues.
Tayebeh Aryafar +6 more
doaj +1 more source
Clarity on the Isoform-Specific Roles of NADPH Oxidases and NADPH Oxidase-4 in Atherosclerosis [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2016 Atherosclerosis is a complex disease that remains a leading cause of death and disability. The formation of vascular plaques arises from the interaction of dyslipidemia with the altered function of blood vessels and immune cells. The exact cause of atherosclerosis is not known, but from the 1950s onward, oxidative modifications of lipids and proteins ...
David J R, Fulton, Scott A, Barman
openaire +2 more sources
Oxidative Injury in Ischemic Stroke: A Focus on NADPH Oxidase 4. [PDF]
Oxid Med Cell Longev, 2022 Ischemic stroke is a leading cause of disability and mortality worldwide. Thus, it is urgent to explore its pathophysiological mechanisms and find new therapeutic strategies for its successful treatment. The relationship between oxidative stress and ischemic stroke is increasingly appreciated and attracting considerable attention.
Li G +11 more
europepmc +4 more sources
Skeletal muscle NADPH oxidase is increased and triggers stretch-induced damage in the mdx mouse. [PDF]
PLoS ONE, 2010 Recent studies have shown that oxidative stress contributes to the pathogenesis of muscle damage in dystrophic (mdx) mice. In this study we have investigated the role of NADPH oxidase as a source of the oxidative stress in these mice.
Nicholas P Whitehead +3 more
doaj +1 more source
Phosphatidylinositol 3-kinase plays a vital role in regulation of rice seed vigor via altering NADPH oxidase activity. [PDF]
PLoS ONE, 2012 Phosphatidylinositol 3-kinase (PI3K) has been reported to be important in normal plant growth and stress responses. In this study, it was verified that PI3K played a vital role in rice seed germination through regulating NADPH oxidase activity ...
Jian Liu, Jun Zhou, Da Xing
doaj +1 more source
NADPH oxidase 4 is an oncoprotein localized to mitochondria [PDF]
Cancer Biology & Therapy, 2010 Reactive oxygen species (ROS) are known to be involved in many physiological and pathological processes. Initially ROS-producing NADPH oxidase (NOX) proteins were thought to be present in phagocytes. However, recent studies have demonstrated that NOX proteins are expressed in many other cell types and tissues.
Kelly A, Graham +6 more
openaire +2 more sources
Redox Biology, 2023 Increasing evidence shows that metabolic factors are involved in the pathological process of osteoarthritis (OA). Lactate has been shown to contribute to the onset and progression of diseases.
Yi-Fan Huang +11 more
doaj +1 more source
Participation of NADPH 4 oxidase in thyroid regulation [PDF]
Molecular and Cellular Endocrinology, 2019 Different factors are involved in thyroid function and proliferation such as thyrotropin (TSH), insulin, growth factors, iodide, etc. TSH and IGF1/insulin increase proliferation rate and stimulate genes involved in thyroid differentiation. In the present study, we analyse the physiological regulation of NOX4 expression by TSH, insulin and iodine, and ...
Oglio, Romina +6 more
openaire +3 more sources
Redox Biology, 2017 Recent clinical studies found a strong association of colonic inflammation and Inflammatory bowel disease (IBD)-like phenotype with NonAlcoholic Fatty liver Disease (NAFLD) yet the mechanisms remain unknown.
Varun Chandrashekaran +9 more
doaj +1 more source
Biomedicines, 2021 The mechanistic target of rapamycin (mTOR) is a nutrient-sensitive cellular signaling kinase that has been implicated in the excess production of reactive oxygen species (ROS).
Justin D. La Favor +3 more
doaj +1 more source