Results 111 to 120 of about 94,270 (218)

The emerging role of the Hippo signaling pathway in interorgan crosstalk

open access: yesThe FEBS Journal, EarlyView.
Hippo signaling functions as a central hub of interorgan communication. Systemic cues from the gut, adipose tissue, and skeletal muscle—including hormones, metabolites, and microbial signals—regulate YAP/TAZ activity in a tissue‐ and context‐dependent manner.
Gahyeon Song   +2 more
wiley   +1 more source

Bringing Gene Therapy Into Real World Clinical Practice

open access: yesHaemophilia, EarlyView.
ABSTRACT Introduction Adeno‐associated virus (AAV)‐based gene therapy for haemophilia has shifted therapeutic paradigms by enabling hepatic gene transfer, restoring endogenous clotting factor expression, and reducing reliance on conventional prophylactic treatments. Two products, valoctocogene roxaparvovec (haemophilia A) and etranacogene dezaparvovec (
Wolfgang Miesbach   +2 more
wiley   +1 more source

sRAGE is associated with low waist circumference and Hb levels in NAFLD

open access: yesOpen Medicine, 2013
Hyogo Hideyuki   +5 more
doaj   +1 more source

Relationship between triglyceride-glucose-derived obesity indices and NAFLD in adolescents: A cross-sectional study. [PDF]

open access: yesMedicine (Baltimore)
Deng W   +8 more
europepmc   +1 more source

Preventive Effect of Mineralocorticoid Receptor Antagonists Against Proteinuria Induced by Atezolizumab Plus Bevacizumab Therapy in Hepatocellular Carcinoma: A Multicenter Retrospective Study

open access: yesHepatology Research, EarlyView.
Mineralocorticoid receptor antagonists are known to reduce proteinuria in chronic kidney disease, but their effectiveness in preventing bevacizumab‐related proteinuria has not been well established. In the present multi‐institutional retrospective study, we found that these agents significantly delay the onset of moderate or higher grade proteinuria ...
Tomoki Hori   +17 more
wiley   +1 more source

Loss of Posterior Occlusal Support Is Associated With Incident Steatotic Liver Disease in a Nationwide Longitudinal Analysis of the JMDC Claims Database

open access: yesHepatology Research, EarlyView.
ABSTRACT Aim Steatotic liver disease (SLD), including metabolic dysfunction–associated SLD (MASLD) and metabolic dysfunction–associated alcohol‐related liver disease (MetALD), is a growing global health burden. Although impaired mastication is linked to metabolic disorders, its role in SLD remains unclear.
Takashi Miyano   +4 more
wiley   +1 more source

Healthcare costs of managing MAFLD are mostly driven by hospitalisation and advanced fibrosis: cost‐analysis from a tertiary‐care, multi‐disciplinary MAFLD clinic

open access: yesInternal Medicine Journal, EarlyView.
Abstract Background and Aims Patients with metabolic (dysfunction)‐associated fatty liver disease (MAFLD) are frequently multimorbid, putting upward pressure on healthcare costs compared to other liver diseases. As Australian data are limited on expenditures in managing MAFLD, we evaluated hospital‐related costs and predictors of costs in patients ...
Natalie Ngu   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy