Results 111 to 120 of about 176,389 (357)

Overlapping Clinical Features Between NAFLD and Metabolic Syndrome in Children [PDF]

, 2014
Non-alcoholic fatty liver disease (NAFLD) is a cluster of pathological liver conditions of emerging importance in overweight and obese children. NAFLD is associated with central obesity, insulin resistance, and dyslipidaemia, which are considered to be ...
Valerio Nobili, Anna Alisi
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Association between PPARGC1A polymorphisms and the occurrence of nonalcoholic fatty liver disease (NAFLD)-2

, 2011
pair of SNPs and are shown as the strand of the LD blocks. The minor allele frequencies of all SNPs used in this analysis were >20%. Each SNP is labeled with its rs number.Copyright information:Taken from "Association between PPARGC1A polymorphisms and ...
Hironori Mawatari (94243), Kunihiro Hosono (94246), Hirokazu Takahashi (94249), Shiro Maeyama (94256), Shingo Kato (94245), Noritoshi Kobayashi (94251), Yuichi Nozaki (94240), Masahiko Inamori (94252), Yasunobu Abe (94253), Kikuko Hotta (94239), Hiroshi Iida (94244), Kyoko Yoneda (94248), Hiroki Endo (94241), Takashi Uchiyama (94242), Koichiro Wada (94257), Masato Yoneda (94238), Kensuke Kubota (94254), Koji Fujita (94247), Satoru Saito (94255), Atsushi Nakajima (94258), Hiroyuki Kirikoshi (94250)   +20 more
core   +1 more source

The liver‐brain axis: A multidimensional regulatory network implicated in Alzheimer's disease pathogenesis and clinical implications

Animal Models and Experimental Medicine, EarlyView.
Schematic diagram of the core pathways of the liver‐brain axis in regulating AD. The liver regulates cerebral Aβ deposition, tau phosphorylation, and neuroinflammation through pathways such as metabolic detoxification (urea cycle, ketone body metabolism, glutathione antioxidant system), molecular secretion (APOE, CRP, FGF21, IGF‐1), and Aβ clearance ...
Ning Zhang, Wei Chen, Meng Wang
wiley   +1 more source

The effects of low-dose IL-2 on Th17/Treg cell imbalance in primary biliary cholangitis mouse models

BMC Gastroenterology
Background/aims Primary biliary cholangitis (PBC) is a chronic cholestatic liver disease. The imbalance of Th17/Treg cells has been reported in PBC patients. Low-dose IL-2 can alleviate disease severity through modulating CD4 + T cell subsets in patients
Zilong Wang, Zhicheng Liu, Jiarui Zheng, Linxiang Huang, Rui Jin, Xiaoxiao Wang, Dongbo Chen, Yandi Xie, Bo Feng   +8 more
doaj   +1 more source

Long-Term Real-World Outcomes of Tenofovir Alafenamide in Chronic Hepatitis B: Detailed Analysis of Treatment-Naive and Experienced Patients

The Korean Journal of Gastroenterology
Background/Aims: This study assessed the long-term efficacy and safety of tenofovir alafenamide (TAF) in real-world settings. Methods: Patients who were candidates for TAF treatment and were followed up at 12-week intervals over 192 weeks were enrolled ...
Yu-Xuan Song, Guang-Jun Song, Hui Ma, Bo Feng, Yan-Di Xie   +4 more
doaj   +1 more source

ZNF143 inhibits hepatocyte mitophagy and promotes non-alcoholic fatty liver disease by targeting increased lncRNA NEAT1 expression to activate ROCK2 pathway

Epigenetics, 2023
Background: Nonalcoholic fatty liver disease (NAFLD) is the most common hepatic disorders worldwide. The mitophagy is suggested to be repressed in NAFLD, but the mechanism remains to be elucidated. Methods: NAFLD cell and mouse models were established by
Yujie Dong, Minjie Hu, Kewei Tan, Rongjuan Dai   +3 more
doaj   +1 more source

Non-alcoholic fatty liver disease in Asian Indian adolescents and young adults: Prevalence and its associated risk factors

Journal of Diabetology, 2021
Background: Non-alcoholic fatty liver disease (NAFLD) is the most common form of chronic liver disease in the youth. The aim of the study was to conduct a metabolic risk factor profiling of NAFLD in adolescents and young adults in Chennai city in south ...
Thaharullah Shah Mehreen, Ranjani Harish, Rajan Kamalesh, Ranjit Mohan Anjana, Viswanathan Mohan   +4 more
doaj   +1 more source

A new perspective on NAFLD: focusing on lipid droplets.

Journal of Hepatology, 2021
Lipid droplets (LDs) are complex and metabolically active organelles. They are composed of a neutral lipid core surrounded by a monolayer of phospholipids and proteins.
E. Scorletti, R. Carr
semanticscholar   +1 more source

Comparative efficacy of GLP‐1 RA, tirzepatide and SGLT‐2 inhibitors in metabolic liver disease: A network meta‐analysis

British Journal of Clinical Pharmacology, EarlyView.
Aim Metabolic liver disease, including nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis, is a major cause of chronic liver dysfunction worldwide, creating an urgent need for effective treatments. This systematic literature review (SLR) and network meta‐analysis (NMA) systematically reviews and compares the efficacy and safety ...
Andrej Belančić, Christina Antza, Anastasios Poutachidis, Smaro Palaska, Elvira Meni Maria Gkrinia, Andrea Katrin Faour, Yusuf Ziya Sener, Seher Sener, Rehena Sultana   +8 more
wiley   +1 more source

Role of nutritional treatment in the management of patient with non-alcoholic fatty liver disease and steatohepatitis

, 2023
reservedUn eccesso calorico e uno stile di vita sedentario hanno portato a un’epidemia globale di obesità e sindrome metabolica. La conseguenza epatica della sindrome metabolica e dell’obesità è la steatosi non alcolica (NAFLD).
PERONI, FEDERICA
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