Results 131 to 140 of about 634,915 (204)

Endothelial C/EBPβ/AEP pathway drives vascular deterioration and systemic aging. [PDF]

Sci Adv
Li B, Nie S, Wang M, An J, Qian Z, Meng X, Edgington-Mitchell LE, Zhang Z, Yang X, Ye K.   +9 more
europepmc   +1 more source

eNAMPT-IFITM3 axis links neuroinflammation to γ-secretase activation. [PDF]

iScience
Hyun J, Jung S, Noh Y, Cho Y, Saido TC, Nah J, Kim KW, Jung YK.   +7 more
europepmc   +1 more source

Artificial Intelligence-Guided Prioritization and Experimental Evaluation of Synergistic Target Combinations for Breast Cancer Therapy. [PDF]

Pharmaceuticals (Basel)
Feng C, Feng Q, She S, Yang R, Li M, Gong L, Rui M.   +6 more
europepmc   +1 more source

Structural basis for a p21-activated kinase 4 and nicotinamide phosphoribosyltransferase dual inhibitor. [PDF]

Acta Crystallogr D Struct Biol
Park J, Hong HR, Han SH, Song J, Son SY, Choi S, Park SM, Lee WK, Jiko C, Kim JH, Jee JG, Bang JK, Park IY, Lee SJ.   +13 more
europepmc   +1 more source

Preclinical efficacy of the novel competitive NAMPT inhibitor STF-118804 in pancreatic cancer. [PDF]

Oncotarget, 2017
Espindola-Netto JM, Chini CCS, Tarragó M, Wang E, Dutta S, Pal K, Mukhopadhyay D, Sola-Penna M, Chini EN.   +8 more
europepmc   +1 more source

Adipose Tissue Overexpression of Nicotinamide Phosphoribosyltransferase Prevents Metabolic Dysfunction in Obese Mice via Extracellular Vesicles. [PDF]

Diabetes
Ferguson D, Gadson EI, Markan KR, Yoshino J, Palacios H, Lin M, Habibi M, Tiash S, Cui X, Kouranova E, Franczak E, Guo Q, Nguyen T, Kealing J, Pietka TA, Liss KHH, Thyfault JP, Patti GJ, Finck BN, Crewe C, Mukherjee S.   +20 more
europepmc   +1 more source

NAD Metabolism in Acute Myeloid Leukaemia: Biological Rationale and Therapeutic Opportunities. [PDF]

Nutrients
Somers K, Karsa M, Moujalled DM.
europepmc   +1 more source

Identification of a novel NAMPT inhibitor by CRISPR/Cas9 chemogenomic profiling in mammalian cells. [PDF]

Sci Rep, 2017
Estoppey D, Hewett JW, Guy CT, Harrington E, Thomas JR, Schirle M, Cuttat R, Waldt A, Gerrits B, Yang Z, Schuierer S, Pan X, Xie K, Carbone W, Knehr J, Lindeman A, Russ C, Frias E, Hoffman GR, Varadarajan M, Ramadan N, Reece-Hoyes JS, Wang Q, Chen X, McAllister G, Roma G, Bouwmeester T, Hoepfner D.   +27 more
europepmc   +1 more source

Physicochemical and Metabolic Optimization of NAMPT Inhibitors Enables Effective Antibody-Drug Conjugates for Liquid and Solid Tumors. [PDF]

ACS Bio Med Chem Au
Ruedas P, Gruss H, Hempelmann A, Vranic M, Neuberth SJ, Petrich V, Gross D, Pálfi A, Pahl AM, Hechler T.   +9 more
europepmc   +1 more source

Metabolic reprogramming of myeloid cells in cancer: from lactate-NAMPT axis to AI-guided therapeutics. [PDF]

Exp Mol Med
Lee IG, Jung K.
europepmc   +1 more source