Results 141 to 150 of about 12,492 (212)

Tiny tools closing the gap: nanobodies in research and therapy. [PDF]

Function (Oxf)
Abdellatif M, Rajurkar J, Leonhardt H.
europepmc   +1 more source

Dynamic Binder Exchange Improves Protein Labeling Efficiency in DNA‐PAINT up to 15‐Fold

Angewandte Chemie International Edition, Volume 65, Issue 11, 9 March 2026.
Dynamic Binder Exchange (DyBE) leverages transient binder–target interactions to enhance labeling efficiency by up to 15‐fold in super‐resolution microscopy. DyBE maps nanoscale receptor tyrosine kinase (RTK) assemblies, including HER2 homodimers and EGFR–HER2 heterodimers, advancing single‐protein spatial proteomics.
Clemens Steinek, Isabelle Pachmayr, Sebastian Strauss, Monique Honsa, Jisoo Kwon, Ralf Jungmann   +5 more
wiley   +1 more source

Redox‐Activated Probes Enable High‐Contrast Live Imaging of Native Postsynaptic Scaffolds

Angewandte Chemie International Edition, Volume 65, Issue 11, 9 March 2026.
Sylives are modified fluorescent peptides for high‐contrast live imaging of inhibitory (gephyrin) and excitatory (PSD‐95) postsynaptic scaffolds in native neurons. Clean labeling requires low nanomolar probe levels, whereas uptake needs micromolar cell‐penetrating peptide (CPP).
Christiane Huhn, Clémence Mille, Sheng‐Yang Ho, Felix Lützenkirchen, Vladimir Khayenko, Melanie Hein, Christian Werner, Matthias Kneussel, Johannes W. Hell, Christian G. Specht, Hans M. Maric   +10 more
wiley   +1 more source

Characterising nanobody developability to improve therapeutic design using the Therapeutic Nanobody Profiler. [PDF]

Commun Biol
Gordon GL, Gervasio J, Souders C, Deane CM.   +3 more
europepmc   +1 more source

Nanobody-based IgG simultaneously inhibit the allergenic and enzymatic activity of the dominant honeybee venom allergen. [PDF]

Nat Commun
Aagaard JB, Gandini R, Ballegaard AR, Jensen BK, Dorn B, Larsen AVB, Lenstrup A, Sønderholm M, Miehe M, Pfützner W, Jakob T, Andersen GR, Möbs C, Spillner E.   +13 more
europepmc   +1 more source

Camelid-Derived Nanobodies Targeting Human Epidermal Growth Factor Receptor: Screening, Expression, and Functional Validation. [PDF]

Antibodies (Basel)
Liu Y, Huang Q, Zhang D, Wang Y, Zhao S, Wen J, Kong Y, Xu J.   +7 more
europepmc   +1 more source

Inhaled nanobodies against COVID-19 [PDF]

Nature Reviews Immunology, 2020
openaire   +2 more sources

Reprogrammed SimCells for antimicrobial therapy. [PDF]

Proc Natl Acad Sci U S A
Dong Y, Ji X, Dong T, Wang Y, Bakkeren E, Foster KR, Huang WE.   +6 more
europepmc   +1 more source

A highly potent and broadly accessible bispecific nanobody for the treatment of ebola virus infections. [PDF]

PLoS Pathog
Bu F, Ye G, Morsheimer K, Turner-Hubbard H, Eaton B, Anantpadma M, Bheemanapally K, Tan C, Davey R, Li F.   +9 more
europepmc   +1 more source

Pfs48/45 nanobodies block Plasmodium falciparum transmission. [PDF]

PLoS Pathog
Lyons FMT, Chmielewski J, Gabriela M, Chan LJ, Tong J, Adair A, Zeglinski K, Gouil Q, Dietrich MH, Tham WH.   +9 more
europepmc   +1 more source