Results 161 to 170 of about 70,422 (295)
BACH1 recruits NANOG and histone H3 lysine 4 methyltransferase MLL/SET1 complexes to regulate enhancer–promoter activity and maintains pluripotency
, 2021 Cong Niu, Siqing Wang, Jieyu Guo, Xiangxiang Wei, Mengping Jia, Zhaoxiong Chen, W. X. Gong, Yue Qin, Xinhong Wang, Xiuling Zhi, Meng Lu, SF Chen, Mingxia Gu, Jianyi Zhang, Jing‐Dong J. Han, Fei Lan, Dan Meng +16 moreopenalex +1 more sourceTumor‐Resident Mast Cells Facilitated Breast Cancer Progression via Activating Type I Interferon Pathway
MedComm – Oncology, Volume 5, Issue 2, June 2026.Breast cancer cell‐derived stem cell factor (SCF) activates c‐KIT‐mediated MAPK/ERK signaling in mast cells, inducing IFNB1 production. Mast cell‐derived IFNB1 then engages the IFNAR1‐STAT1 axis in breast cancer cells, activating the Type I interferon pathway to promote tumor stemness and progression.Siqin Li, Juchuanli Tu, Ruoyi Ding, Xueyan He, Xian Zhang, Mengxue Dong, Fengkai Li, Wen Yi, Yuwei Tao, Wei Ma, Zhijun Dai, Zhenhua Chen, Yuan Wang, Xiongbin Lu, Jian Liu, Suling Liu, Jiahui Xu +16 morewiley +1 more sourceZinc‐Coordination‐Driven Pyroptosis Nano‐Inductor Sensitizes Colorectal Cancer Chemo‐Immunotherapy by Specific Delivery and Cell Stemness Suppression
MedComm – Oncology, Volume 5, Issue 2, June 2026.CD44‐targeted CNPs co‐deliver Zn2+ and MIT–ALA to CRC cells. Intracellularly, Zn2+ inhibits GLUT1‐dependent glycolysis, and ALA disrupts mitochondrial function, driving metabolic exhaustion in CSCs. This mitochondrial damage primes GSDMD‐mediated pyroptosis, accompanied by the release of pro‐inflammatory cytokines (IL‑1β, IL‑18).Qinxia Chang, Wenting Cheng, Hailong Tian, Siyuan Qin, Yaying Zhang, Jing Zuo, Wenbing Pu, Shuaijun Lu, Na Xie +8 morewiley +1 more sourceSupplementary Data from ERK-Mediated Loss of miR-199a-3p and Induction of EGR1 Act as a “Toggle Switch” of GBM Cell Dedifferentiation into NANOG- and OCT4-Positive Cells
, 2023 Fabien Almairac, Laurent Turchi, Nathalie Sakakini, David Nicolas Debruyne, Sarah Elkeurti, Elisabet Gjernes, Béatrice Polo, Laurence Bianchini, Denys Fontaine, Philippe Paquis, Hervé Chneiweiss, Marie‐Pierre Junier, Patrick Verrando, Fanny Burel‐Vandenbos, Thierry Virolle +14 moreopenalex +1 more sourceSupplementary Methods from <i>MYC</i> Regulates the <i>HIF2α</i> Stemness Pathway via <i>Nanog</i> and <i>Sox2</i> to Maintain Self-Renewal in Cancer Stem Cells versus Non-Stem Cancer Cells
, 2023 Bikul Das, Bidisha Pal, Rashmi Bhuyan, Hong Li, Anupam Sarma, Sukanya Gayan, Joyeeta Talukdar, Sorra Sandhya, Seema Bhuyan, Gayatri Gogoi, Arvin M. Gouw, Debabrat Baishya, Jason Gotlib, Amal Chandra Kataki, Dean W. Felsher +14 moreopenalex +1 more source
