Results 161 to 170 of about 11,262 (208)
Periodontology 2000, EarlyView.Abstract Orthodontic therapy applies forces to teeth, causing an inflammatory reaction in the periodontal ligament. This is repaired by remodeling of the periodontium, allowing tooth displacement. Although orthodontic therapy is mostly initiated during childhood and adolescence, the number of adults seeking this treatment is increasing as our society's
Ludovica Parisi +4 more
wiley +1 more source
Understanding extracellular vesicles in antiaging
Periodontology 2000, EarlyView.Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad +3 more
wiley +1 more source
Clinical and Translational Medicine, Volume 16, Issue 11, November 2026.• DNMT3A‐mediated PDLIM4 promoter hypermethylation is an early event in colorectal tumorigenesis. • Restoring PDLIM4 suppresses CRC proliferation and stemness while promoting apoptosis in vitro and in vivo. • PDLIM4 promotes the autophagic‐lysosomal degradation of BTF3 and restrains PI3K/Akt signalling.
Jiaxing Wang +10 more
wiley +1 more source
Protein Lactylation in Cancer: From Mechanisms to Therapy
MedComm, Volume 7, Issue 11, November 2026.Increased glycolysis and lactate accumulation promote histone and nonhistone protein lactylation, linking tumor metabolic reprogramming to treatment adaptation. Lactylation enhances DNA repair, suppresses antitumor immunity, strengthens antioxidant defenses, and facilitates cell‐cycle checkpoint escape, collectively promoting resistance to chemotherapy,
Wentian Huang +8 more
wiley +1 more source
Regulation of NANOG in Cancer Cells [PDF]
Molecular Carcinogenesis, 2015 As one of the key pluripotency transcription factors, NANOG plays a critical role in maintaining the self‐renewal and pluripotency in normal embryonic stem cells. Recent data indicate that NANOG is expressed in a variety of cancers and its expression correlates with poor survival in cancer patients. Of interest,
Dean Tang, Collene R Jeter, Qingxia Fan
exaly +3 more sources