Results 61 to 70 of about 19,127 (228)

Naringin Ameliorates Monocrotaline-Induced Pulmonary Arterial Hypertension Through Endothelial-To-Mesenchymal Transition Inhibition

Frontiers in Pharmacology, 2021
Pulmonary arterial hypertension (PAH) caused by enhanced arterial pressure increases vessel resistance in the lung. Endothelial-to-mesenchymal transition (EndMT) plays key roles in the vascular remodeling in PAH.
Yonghui Wu, Changhong Cai, Yijia Xiang, Huan Zhao, Lingchun Lv, Chunlai Zeng   +5 more
doaj   +1 more source

α‐Glucosidase Inhibitory Potential of Citrus reticulata Peel‐Derived Flavonoids—A Prelude for the Management of Type 2 Diabetes [PDF]

Food Sci Nutr
Flavonoids derived from Citrus reticulate peel inhibit α‐glucosidase activity, delaying carbohydrate digestion and reducing glucose absorption, thereby indicating their potential as functional food components for type 2 diabetes management. ABSTRACT α‐Glucosidase inhibitors (AGIs) are compounds used to treat type 2 diabetes (T2D) by preventing the ...
Baloyi I, Rabbad A, Gama N, Malgas S.
europepmc   +2 more sources

Mechanism of action of an antioxidant active packaging prepared with Citrus extract [PDF]

, 2014
yesActive packaging consisting of polyethylene terephthalate (PET) trays coated with a Citrus extract, without and with plasma pre-treatment, can reduce lipid oxidation in cooked meat.
Contini, C., Dowling, D.P., Katsikogianni, Maria G., Monahan, F.J., O'Neill, F.T., O'Sullivan, M.   +5 more
core   +1 more source

Application Strategies of Bone Marrow Mesenchymal Stromal Cells in Bone‐Related Diseases

Cell Proliferation, EarlyView.
Engineered BMSCs and vesicles enhance therapy effects for bone diseases via multi‐strategic approaches. ABSTRACT Bone‐related diseases (e.g., osteoporosis, osteoarthritis and fractures) exhibit a rising global incidence, imposing significant burdens on both quality of life and healthcare systems.
Xuemei Long, Dan Tan, Qianke Tao, Qiaonan Ye, Luwen Ye, Qing Li, Jingang Xiao   +6 more
wiley   +1 more source

Naringin Protects Against High Glucose-Induced Human Endothelial Cell Injury Via Antioxidation and CX3CL1 Downregulation

Cellular Physiology and Biochemistry, 2017
Background/Aims: The induction of endothelial injury by hyperglycemia in diabetes has been widely accepted. Naringin is a bio-flavonoid. Some studies showed that naringin alleviates diabetic complications, but the exact mechanisms by which naringin ...
Guilin Li, Yurong Xu, Xuan Sheng, Hua Liu, Jingjing Guo, Jiayue Wang, Qi Zhong, Huaide Jiang, Chaoran Zheng, Mengxia Tan, Shenqiang Rao, Yanling Yu, Yun Gao, Guodong Li, Shangdong Liang, Gaochun Zhu   +15 more
doaj   +1 more source

Dietary anthocyanidin pelargonidin activates G protein‐coupled receptor 35

The FEBS Journal, EarlyView.
Pelargonidin, a red‐fruit‐derived anthocyanidin, was newly identified as a dietary agonist of GPR35, a metabolite‐sensing GPCR implicated in anti‐inflammation. Through screening of dietary compounds, pelargonidin emerged as a potent GPR35 agonist, attenuating inflammation in human intestinal cells.
Fumie Nakashima, Sayako Shimomura, Mayuka Wakabayashi, Wei Qi Loh, Harumi Ando, Haruka Sei, Hiroyuki Hattori, Didik Huswo Utomo, Masaki Kita, Asuka Inoue, Koji Uchida, Takahiro Shibata   +11 more
wiley   +1 more source

Naringin Mediates Adult Hippocampal Neurogenesis for Antidepression via Activating CREB Signaling

Frontiers in Cell and Developmental Biology, 2022
The brain-derived neurotrophic factor/tropomyosin receptor kinase B/cAMP response element-binding protein (BDNF/TrkB/CREB) signaling pathway is a critical therapeutic target for inducing adult hippocampal neurogenesis and antidepressant therapy.
Chong Gao, Chong Gao, Meiling Wu, Qiaohui Du, Jiagang Deng, Jiangang Shen   +5 more
doaj   +1 more source

Escobajos de la vid como fuente de compuestos fenólicos con propiedades antioxidantes [PDF]

, 2019
Winemaking industry generates considerable amounts of bunch stems that are usually wasted despite their potential value as source of bioactive compounds. Phenolic profiles and antioxidant capacity (AC) of bunch stem extracts from eight grape varieties of
Bottini, Ambrosio Rubén, Ferreyra, Susana Gisela, Fontana, Ariel Ramón   +2 more
core  

Pharmacokinetics, Tissue Distribution, Metabolism, and Excretion of Naringin in Aged Rats

Frontiers in Pharmacology, 2019
Aging is an inevitable biological process characterized by the loss of functional capacity and associated with changes in all phases of pharmacokinetic processes. Naringin, a dietary flavanone glycoside, has been proved to be beneficial for the treatment
Xuan Zeng, Weiwei Su, Yuying Zheng, Yudong He, Yan He, Hongyu Rao, Wei Peng, Hongliang Yao   +7 more
doaj   +1 more source

Metabolo‐Transcriptomics Analyses Reveal Alfalfa Adaptation to Combined Saline‐Alkali and Low‐Temperature Stress in the Field

Plant Biotechnology Journal, EarlyView.
ABSTRACT Alfalfa (Medicago sativa L.) is known as the ‘King of Forage’ because of its high protein content and excellent palatability. Alfalfa productivity is adversely affected in cold regions with saline‐alkali soils. However, the mechanisms underlying the response of alfalfa to combined saline‐alkali and low‐temperature stress under field conditions
Rui Guo, Lei Liu, Jiaqi Li, Hongyu Qu, Weileng Guo, Lishuang Zhang, Dihe Yang, Ruixin Wang, Changhong Guo   +8 more
wiley   +1 more source