Exploring and Targeting the Connection of Iron and Copper Homeostasis to Neurodegenerative Diseases
Iron and copper dyshomeostasis, along with their interactions with key intrinsically disordered proteins (e.g., Aβ, tau, α‐synuclein) have a strong implication in the onset and progression of neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD), Prion diseases (PrDs), Huntington's disease (HD), Wilson's disease (WD),
Xin Liu +9 more
wiley +1 more source
Naringin Mediates Adult Hippocampal Neurogenesis for Antidepression via Activating CREB Signaling
The brain-derived neurotrophic factor/tropomyosin receptor kinase B/cAMP response element-binding protein (BDNF/TrkB/CREB) signaling pathway is a critical therapeutic target for inducing adult hippocampal neurogenesis and antidepressant therapy.
Chong Gao +5 more
doaj +1 more source
Hydrophilic antioxidant compounds in orange juice from different fruit cultivars: Composition and antioxidant activity evaluated by chemical and cellular based (Saccharomyces cerevisiae) assays [PDF]
Antioxidant capacity was evaluated by a cellular model (Saccharomyces cerevisiae) and chemical methods (FRAP, TEAC and total phenols by Folin-Ciocalteu assay) in the hydrophilic fraction (phenolic compounds and ascorbic acid) of orange juices (OJs ...
Amari +50 more
core +2 more sources
Naringin mitigates testicular injury and associated neuronal toxicity in lead-exposed cockerel chicks [PDF]
Objective: Lead (Pb) poisoning affects multiple organs including the reproductive system. The experiment was performed to explore the protective effect of naringin on testicular apoptosis, neuronal dysfunction and markers of stress in cockerel chicks ...
Oluwaseun Esan +10 more
doaj +1 more source
On the Use of Gallic Acid as a Potential Natural Antioxidant and Ultraviolet Light Stabilizer in Cast-Extruded Bio-Based High-Density Polyethylene Films [PDF]
This study originally explores the use of gallic acid (GA) as a natural additive in bio-based high-density polyethylene (bio-HDPE) formulations. Thus, bio-HDPE was first melt-compounded with two different loadings of GA, namely 0.3 and 0.8 parts per ...
Balart, Rafael +5 more
core +2 more sources
Chronic inflammation in diabetic foot ulcers elevates MMP activity and suppresses TIMP and growth factor signaling, impairing tissue repair. Phytochemicals modulate NF‐κB/MAPK pathways and enhance Nrf2–TIMP expression, restoring MMP/TIMP balance, promoting collagen deposition, angiogenesis, and re‐epithelialization, leading to effective wound healing ...
Vishnu Priyan Elaiyaraja +3 more
wiley +1 more source
Forty Assaf fattening lambs (initial age 13 to 15 weeks) offered a diet of barley straw and a commercial concentrate were used to assess the effect of naringin (a type of citrus flavonoid with proven antioxidant, antimicrobial and anti-inflammatory ...
Ó. López-Campos +5 more
doaj +1 more source
Effects of flavonoids dietary supplementation on egg yolk antioxidant capacity and cholesterol level [PDF]
An experiment was conducted to examine the effects of supplementing laying hen feed with different levels of hesperidin or naringin, bioflavonoids that are abundant and inexpensive by-products of citrus cultivation, on the yolk antioxidant capacity and ...
Charismiadou, M. +6 more
core
Determination of phytochemical contains of Prunus cerasifera cv. “Pissardi Nigra” [PDF]
Kiraz veya süs erik olarak da bilinen Prunus cerasifera cv. “Pissardi Nigra, karışık ve dikenli dallara sahip küçük bir çalımsı ağaç yapısına sahiptir ve erik gibi yenilebilir meyveleri vardır.
Göztok, Ferda, Kırbağ, Sevda
core +1 more source
Abstract The genus Citrus is characterized by a reticulate evolutionary history with frequent hybridization, making it an intriguing subject for genome evolution investigation. Citrus changshan‐huyou Y. B. Chang (Huyou) is a unique landrace first discovered in Zhejiang Province, China, with premium fruit quality.
Zhanghui Zeng +14 more
wiley +1 more source

