Results 91 to 100 of about 79,016,594 (203)

AKT Phosphorylation of FOXK2 at Ser398 Impacts Breast Cancer Cell Growth and Viability

open access: yesThe FASEB Journal, Volume 40, Issue 20, 31 October 2026.
Higher FOXK2 protein levels are associated with increased AKT phosphorylation and chemoresistance in breast cancer cells. AKT modulates FOXK2 protein levels, with no such regulation in FOXK2 mRNA levels. GSK3β, a known substrate of AKT (dotted arrow), does not regulate FOXK2 in our cellular model.
L. T. Carneiro   +10 more
wiley   +1 more source

Rapid Multiplex Antimicrobial Resistance Profiling and Bacterial Identification by LAP‐MALDI Mass Spectrometry Biotyping

open access: yesAdvanced Science, Volume 13, Issue 60, 28 October 2026.
Liquid atmospheric pressure matrix‐assisted laser desorption/ionization (LAP‐MALDI) mass spectrometry (MS) provides multiplexed biotyping of microbial cultures using a fast and simple workflow. This is demonstrated for clinically relevant bacteria, resulting in accurate antimicrobial resistance (AMR) detection, speciation by MS/MS sequencing and ...
Lily R. Adair   +3 more
wiley   +1 more source

First Reported Nosocomial Outbreak Of NDM-5-Producing Klebsiella pneumoniae In A Neonatal Unit In China.

open access: yesInfection and drug resistance, 2019
Carbapenem-resistant Klebsiella pneumoniae (CRKP) have emerged worldwide and also being a major threat to children and neonate. In this study, we describe a nosocomial outbreak of NDM-5-producing Klebsiella pneumoniae in neonatal unit of a teaching hospital in China from September 2015 to September 2016.We collected 12 carbapenem-resistant K ...
Kong,Ziyan   +6 more
openaire   +4 more sources

Genomic Characteristics of a Klebsiella pneumoniae Strain Coproducing Carbapenemases KPC-2 and NDM-5

open access: yes, 2022
Abstract The aim of this study was to characterize the resistance gene of a Klebsiella pneumoniae strain coproducing carbapenemases KPC-2 and NDM-5.Klebsiella pneumoniae KPN-hnqyy, which is separated from the stool specimen of a patient, is resistant to all carbapenem antibiotics. Its MLST type is ST11.
Wei-qiang Xiao   +5 more
openaire   +1 more source

Acorus calamus L. for Cognitive Enhancement: A Systematic Review of Its Ethnobotanical Practices and Scientific Evidence

open access: yesChemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Acorus calamus is an important medicinal plants having a wide range of biological properties. Traditionally, the plant is commonly used to treat various diseases including fever, cold, pain and swelling, stomach problem, etc. The major compound found in the plant is β‐ asarone.
Raghu Tamang   +3 more
wiley   +1 more source

Plasmid-Mediated Novel bla NDM-17 Gene Encoding a Carbapenemase with Enhanced Activity in a Sequence Type 48 Escherichia coli Strain [PDF]

open access: yes, 2017
Carbapenem-resistant Enterobacteriaceae (CRE) have spread worldwide, leaving very few treatment options available. New Delhi metallo-beta-lactamase (NDM) is the main carbapenemase mediating CRE resistance and is of increasing ...
Shen, Jianzhong   +19 more
core   +1 more source

VirBR, a transcription regulator, promotes IncX3 plasmid transmission, and persistence of bla NDM-5 in zoonotic bacteria

open access: yesNature Communications
IncX3 plasmids carrying the New Delhi metallo-β-lactamase-encoding gene, bla NDM-5, are rapidly spreading globally in both humans and animals. Given that carbapenems are listed on the WHO AWaRe watch group and are prohibited for use in animals, the ...
Tengfei Ma   +13 more
doaj   +1 more source

New Delhi Metallo-β-Lactamase 5–Producing Klebsiella pneumoniae Sequence Type 258, Southwest China, 2017

open access: yesEmerging Infectious Diseases, 2019
We isolated a New Delhi metallo-β-lactamase 5 (NDM-5)–producing Klebsiella pneumoniae sequence type (ST) 258 strain in southwest China during 2017. The blaNDM-5 gene was acquired by horizontal plasmid transfer from NDM-5–producing Escherichia coli.
Xin Zhang   +9 more
doaj   +1 more source

Divergent Root and Shoot Trait Strategies Shape Competition–Facilitation Shifts Between Conspecific and Heterospecific Neighbors Under Contrasting Soil Moisture Conditions

open access: yesEcology and Evolution, Volume 16, Issue 10, October 2026.
Soil moisture availability strongly influences plant–plant interactions, yet the role of coordinated root and shoot traits in shaping competition and facilitation remains poorly understood. Using a 7‐month glasshouse experiment with four tropical legume species, we demonstrate that soil moisture and neighbor identity jointly regulate plant strategies ...
Jan Sher   +5 more
wiley   +1 more source

Klebsiella pneumoniaeCo-Producing NDM-5 and OXA-181 Carbapenemases, South Korea

open access: yesEmerging Infectious Diseases, 2015
To the Editor: Carbapenemase-producing Enterobacteriaceae are being reported worldwide. Travel, medical tourism, and cross-border transfer of patients might play a role in the spread of these bacteria (1,2). Klebsiella pneumoniae co-producing New Delhi metallo-β-lactamase 5 (NDM-5) and oxacillinase 181 (OXA-181) carbapenemases was detected in South ...
Sun Young Cho   +8 more
openaire   +2 more sources

Home - About - Disclaimer - Privacy