Results 71 to 80 of about 79,016,594 (203)

Clinical Course and Predictors of Biologic Therapy, Hospitalisation and Surgery: A Five‐Year Prospective Study in Newly Diagnosed Inflammatory Bowel Disease

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
In this large multicentre Spanish inception cohort, biologics/JAK inhibitors were frequently used during the first 5 years after inflammatory bowel disease diagnosis and were associated with reduced hospitalisation risk, although not with lower abdominal surgery rates.
Ana Garre   +308 more
wiley   +1 more source

Characteristics of Carbapenemase-Producing Klebsiella pneumoniae Isolated in the Intensive Care Unit of the Largest Tertiary Hospital in Bangladesh

open access: yesFrontiers in Microbiology, 2021
For addressing the issue of antimicrobial drug resistance in developing countries, it is important to investigate the characteristics of carbapenemase-producing organisms.
Takashi Okanda   +9 more
doaj   +1 more source

The Ahlqvist Subphenotypes of Type 2 Diabetes: A Narrative Review of Scientific Evidence and Its Potential Contribution to Precision Diabetes

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Background Among several approaches, k‐means clustering has established as a widely used method to classify people with type 2 diabetes (T2D) into distinct subphenotypes, and the Ahlqvist T2D subphenotypes of Severe Insulin Deficient Diabetes (SIDD), Mild Age‐Related Diabetes (MARD), Mild Obesity Diabetes (MOD) and Severe Insulin Resistant ...
Wolfgang Landgraf   +3 more
wiley   +1 more source

Nosocomial Outbreak Caused by NDM-5 and OXA-181 Carbapenemase Co-producing Escherichia coli [PDF]

open access: yesInfection & Chemotherapy, 2019
Carbapenemase-producing Enterobacteriaceae (CPE) is an important and increasing threat to global health. From July to September 2017, 20 inpatients at a tertiary care hospital in Korea were either colonized or infected with carbapenem-resistant Escherichia coli strains. All of E. coli isolates co-produced blaNDM-5 and blaOXA-181 carbapenemase genes and
Kwangjin Ahn   +6 more
openaire   +3 more sources

Evolution for improved secretion and fitness may be the selective pressures leading to the emergence of two NDM alleles

open access: yes, 2020
The New Delhi metallo-β-lactamase (NDM-1) mediates resistance to β-lactam antibiotics. NDM-1 was likely formed as the result of a gene fusion between sequences encoding the first six amino acids of cytoplasm-localised aminoglycosidase, AphA6, and a ...
Nouwens, Amanda S.   +11 more
core   +1 more source

Molecular epidemiology of Carbapenem-resistant Klebsiella pneumoniae in a paediatric hospital in China

open access: yesInternational Journal of Infectious Diseases, 2020
Objective: We investigated the epidemiological characteristics of drug resistance and virulence factors of carbapenem-resistant Klebsiella pneumoniae (CRKP) isolates from paediatric patients in Shanghai. Methods: CRKP strains were consecutively collected
Bingjie Wang   +7 more
doaj   +1 more source

What Is the Clinical Periodontal Condition of Patients With Diabetes Mellitus as Compared to Those Without?—A Synthesis of Systematic Reviews

open access: yesInternational Journal of Dental Hygiene, EarlyView.
ABSTRACT Focused Question What is the clinical periodontal condition of patients with diabetes mellitus (DM) as compared to those without DM (NDM) as gathered from existing systematic reviews (SRs)? Methods MEDLINE‐PubMed and the Cochrane Library were searched from inception through September 2024 to identify eligible studies.
Lotte P. M. Weijdijk   +3 more
wiley   +1 more source

Increasing New Delhi metallo-β-lactamase-positive Escherichia coli among carbapenem non-susceptible Enterobacteriaceae in Taiwan during 2016 to 2018

open access: yesScientific Reports, 2021
New Delhi metallo-β-lactamase (NDM) had been reported to be the predominant carbapenemase among Escherichia coli in Taiwan. However, studies focusing on the clonal background and epidemiology of plasmids carrying NDM genes were limited.
Yu-Shan Huang   +8 more
doaj   +1 more source

Shape of Water: Power Dynamics for Supply Chain Resilience

open access: yesJournal of Supply Chain Management, EarlyView.
ABSTRACT The world is facing climate change‐driven disruptions such as extreme weather events, which affect nature as well as firms and their supply chains. Nonetheless, little is known about how supply chain players shape their socioecological resilience, including from a power perspective.
Aristides R. Oliveira Junior   +3 more
wiley   +1 more source

Genomic characterization of an NDM-9-producing Acinetobacter baumannii clinical isolate and role of Glu152Lys substitution in the enhanced cefiderocol hydrolysis of NDM-9

open access: yes, 2023
International audienceHere, we characterized the first French NDM-9-producing Acinetobacter baumannii isolate. A. baumannii 13A297, which belonged to the ST$^{Pas}$25 (international clone IC7), was highly resistant to β-lactams including cefiderocol (MIC
Gaillot, Susie   +21 more
core   +1 more source

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