Results 181 to 190 of about 27,017 (217)
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Molecular Diversity of NDM-1, NDM-5, NDM-6, and NDM-7 Variants of New Delhi Metallo-β-Lactamases and Their Impact on Drug Resistance

Clinical Laboratory, 2021
The emergence of multidrug-resistant bacteria has become a serious healthcare problem worldwide.In this study, 192 clinical specimens collected from a tertiary hospital in Al Jouf, Saudi Arabia were processed in order to isolate gram-negative bacteria.
openaire   +2 more sources

NDM-1 Hazard in the Balkan States: Evidence of the First Outbreak of NDM-1-Producing Klebsiella pneumoniae in Bulgaria

open access: yesMicrobial Drug Resistance, 2018
New Delhi MBL (NDM) carbapenemase-producing Klebsiella pneumoniae has become one of the most concerning multidrug-resistant pathogens. The Balkan counties are considered a reservoir for the spread of such strains based on several reports documenting NDM ...
Lida Politi   +2 more
exaly   +2 more sources

Recent research and development of NDM-1 inhibitors

European Journal of Medicinal Chemistry, 2021
Bacteria carrying New Delhi metallo-β-lactamase-1 (New Delhi metallo-β-lactamase, NDM-1) resistance gene is a new type of "superbug", which can hydrolyze almost all β-lactam antibiotics, rapidly spread among the same species and even spread among different species. NDM-1 belongs to the class B1 broad-spectrum enzyme of β-lactamase.
Ting, Wang   +5 more
openaire   +2 more sources

Balkan NDM-1: escape or transplant?

The Lancet Infectious Diseases, 2011
164 www.thelancet.com/infection Vol 11 March 2011 4 Sadetzki S, Chetrit A, Lubina A, et al. Risk of thyroid cancer after childhood exposure to ionizing radiation for tinea capitis. J Clin Endocrinol Metab 2006; 91: 4798–04. 5 Boaventura P, Bastos J, Pereira D, et al.
Livermore, David M.   +3 more
openaire   +4 more sources

The Dissemination of NDM-1 in Acinetobacter baumannii Strains

Current Microbiology, 2022
Acinetobacter baumannii is a common pathogen in hospitals and usually causes bacteremia, pneumonia, meningitis, peritonitis and other diseases. Isolates carried NDM-1 gene can make several antibiotics such as carbapenems and other beta-lactams ineffective. Nowadays, the number of A.
Na, Liu   +4 more
openaire   +2 more sources

Dissemination of NDM-producing bacteria in Southern Brazil

Diagnostic Microbiology and Infectious Disease, 2023
The dissemination of NDM-1 carbapenemases (New Delhi Metallo-β-lactamase) is a global public health problem, mainly in developing countries. The aim of this study was to characterize the spread of NDM-producing bacteria in the Southern Brazilian states analyzing epidemiological, molecular, and antimicrobial susceptibility aspects.A total of 10,684 ...
Lavinia N.V.S. Arend   +11 more
openaire   +2 more sources

NDM-1 — A Cause for Worldwide Concern

New England Journal of Medicine, 2010
NDM-1 (New Delhi metallo-beta-lactamase 1), a genetic element encoding multiple-resistance genes, has been found in various Enterobacteriaceae, rendering them resistant to nearly all antimicrobial agents. Success in combating antibiotic-resistant superbugs has been limited.
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Evolutionary insights into NDM variants: Identification and functional analysis of novel NDM-58 in Pseudomonas aeruginosa

Microbial Pathogenesis
The emergence of New Delhi Metallo-β-lactamase (NDM) variants in P. aeruginosa has significantly contributed to carbapenem resistance, posing a global threat to antimicrobial therapy. The catalytic activity of NDM, dependent on Zn (II), is enhanced by specific mutations. In this study, we report the identification and characterization of a novel NDM-58
Maruthan, Karthik   +7 more
openaire   +2 more sources

NDM-9 resistance to taniborbactam

The Lancet Infectious Diseases, 2023
Christophe, Le Terrier   +4 more
openaire   +2 more sources

Enigmatic occurrence of NDM-7 enzyme in the community

International Journal of Antimicrobial Agents, 2016
A 79-year-old French woman living in a nursing home was brought to the hospital emergency room for indwelling urinary catheter re-insertion following accidental removal. Despite no clinical signs suggesting infection, urine was sent to the laboratory for microbiological and cytological analysis.
van Der Mee-Marquet, Nathalie   +4 more
openaire   +4 more sources

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