Results 41 to 50 of about 63,496 (250)

Detection of NDM Variants (blaNDM-1, blaNDM-2, blaNDM-3) from Carbapenem-Resistant Escherichia coli and Klebsiella pneumoniae: First Report from Nepal

Infection and Drug Resistance, 2022
Increasing burden of carbapenem resistance among Enterobacterales is attributable to their ability to produce carbapenemase enzymes like metallo-beta-lactamase (MBL), Klebsiella pneumoniae carbapenemase (KPC), and OXA-type. This study aimed to determine the prevalence of carbapenemases and MBL genes ((bla NDM-1, bla NDM-1 and bla NDM-3) among E.
Anisha Thapa, Milan Kumar Upreti, Nabin Kishor Bimali, Basudha Shrestha, Anil Kumar Sah, Krishus Nepal, Binod Dhungel, Sanjib Adhikari, Nabaraj Adhikari, Binod Lekhak, Komal Raj Rijal   +10 more
openaire   +4 more sources

NDM-35-Producing ST167 Escherichia coli Highly Resistant to β-Lactams Including Cefiderocol

Antimicrobial Agents and Chemotherapy, 2022
A multidrug-resistant (carbapenems, aztreonam + avibactam, and cefiderocol) ST167 Escherichia coli clinical isolate recovered from a patient hospitalized in Switzerland produced NDM-35 showing ca.
L. Poirel, José Manuel Ortiz de la Rosa, Zeynep Sakaoglu, Ayda Kusaksizoglu, Mustafa Sadek, P. Nordmann   +5 more
semanticscholar   +1 more source

Clinical Evolution of New Delhi Metallo-β-Lactamase (NDM) optimizes resistance under Zn(II) Deprivation [PDF]

, 2018
Carbapenem-resistant Enterobacteriaceae (CRE) are rapidly spreading and taking a staggering toll on all health care systems, largely due to the dissemination of genes coding for potent carbapenemases.
Bahr, Guillermo, Bethel, Christopher R., Bonomo, Robert A., Gonzalez, Lisandro Javier, Vila, Alejandro Jose, Vitor Horen, Luisina   +5 more
core   +1 more source

The transferability and evolution of NDM-1 and KPC-2 co-producing Klebsiella pneumoniae from clinical settings

EBioMedicine, 2020
Background Emergence of KPC-2 and NDM-1-coproducing carbapenem-resistant Klebsiella pneumoniae (KPC-2-NDM-1-CRKP) has escalated threat of CRKP to healthcare. Currently, only 4 isolates had been reported sporadically.
Hua Gao, Yudong Liu, Ruobing Wang, Qi Wang, Longyang Jin, Hui Wang   +5 more
semanticscholar   +1 more source

High prevalence of fungal and NDM-OXA producing Gram-negative bacterial superinfections in the second wave of coronavirus disease 2019 in India: Experience from a dedicated coronavirus disease 2019 hospital in North India

Journal of Global Infectious Diseases, 2022
Introduction: During the second wave of coronavirus disease 2019 (COVID-19), superinfection caused by fungus and multidrug-resistant bacteria worsened the severity of illness in COVID-19 patients.
Omika Katoch, Neha Sharad, Parul Singh, Sharad Srivastav, Richa Aggrawal, Rajesh Malhotra, Purva Mathur   +6 more
doaj   +1 more source

In Silico and In Vitro Screening of Natural Compounds as Broad-Spectrum β-Lactamase Inhibitors against Acinetobacter baumannii New Delhi Metallo-β-lactamase-1 (NDM-1)

BioMed Research International, 2022
Antibiotic resistance is one of the significant problems globally; there is an increase in resistance with introducing every new class of antibiotics. Further, this has become one of the reasons for arising of new resistance mechanisms in Acinetobacter ...
Aparna Vasudevan, D. Kesavan, Liang Wu, Zhaoliang Su, Shengjun Wang, M. Ramasamy, W. Hopper, Huaxi Xu   +7 more
semanticscholar   +1 more source

NDM-1–ProducingKlebsiella pneumoniae, Croatia [PDF]

Emerging Infectious Diseases, 2012
Objectives: A K. pneumoniae strain, resistant to carbapenems, was isolated in May 2009, from a blood culture of a 40-years-old man, recovered in a surgical intensive care unit of the Clinical Hospital Center in Zagreb, Croatia.The patient had been transferred from another hospital of a neighbouring country after 5 days of hospitalization due to a car ...
MAZZARIOL, Annarita, Bosnjak Z., Ballarini P., Budimir A., Bedenic B., Kalenic S., CORNAGLIA, Giuseppe   +6 more
openaire   +3 more sources

Rapid Screening for Carbapenem Resistant Organisms: Current Results and Future Approaches [PDF]

Journal of Clinical and Diagnostic Research, 2015
Carbapenem producing Enterobacteriaceae (CPE) is a major public health threat. A total of 120 carbapenem resistant E.coli (n=32) and K.pneumoniae (n=88) from blood stream infections were screened for the presence of carbapenem resistant genes KPC, NDM ...
Shalini Anandan, Sunganya Damodaran, Radha Gopi, Yamuna Devi Bakthavatchalam, Balaji Veeraraghavan   +4 more
doaj   +1 more source

The roles of mitochondrial tRNA mutations in non-dystrophic myotonias

Mitochondrial DNA. Part B. Resources, 2020
According a recent report by Heidari et al., a mutational screening for candidate pathogenic mitochondrial tRNA (mt-tRNA) mutations were performed in 45 Iranian patients with non-dystrophic myotonia (NDM) and 70 control subjects.
Xue-Jiao Yu, Yu Ding
doaj   +1 more source

NDM-1 encoded by a pNDM-BJ01-like plasmid p3SP-NDM in clinical Enterobacter aerogenes [PDF]

Frontiers in Microbiology, 2015
A carbapenem-nonsusceptible Enterobacter aerogenes strain named 3-SP was isolated from a human case of pneumonia in a Chinese teaching hospital. NDM-1 carbapenemase is produced by a pNDM-BJ01-like conjugative plasmid designated p3SP-NDM to account for carbapenem resistance of 3-SP. p3SP-NDM was fully sequenced and compared with all publically available
Chen, Zhenhong, Li, Hongxia, Feng, Jiao, Li, Yuxue, Chen, Xin, Guo, Xuemin, Chen, Weijun, Wang, Li, Lin, Lei, Yang, Huiying, Yang, Wenhui, Wang, Jie, Zhou, Dongsheng, Liu, Changting, Yin, Zhe   +14 more
openaire   +3 more sources