Near-Infrared Photoimmunotherapy for Oropharyngeal Cancer [PDF]
Cancers, 2022 Human papillomavirus (HPV)-associated oropharyngeal cancer has a better prognosis than other head and neck cancers. However, rates of recurrence and metastasis are similar and the prognosis of recurrent or metastatic HPV-associated oropharyngeal cancer is poor.
Daisuke Nishikawa +2 more
exaly +5 more sources
Near-infrared photoimmunotherapy in cancer treatment: a bibliometric and visual analysis [PDF]
Frontiers in PharmacologyBackgroundNear-infrared photoimmunotherapy (NIR-PIT) is an emerging cancer treatment technology that combines the advantages of optical technology and immunotherapy to provide a highly effective, precise, and low side-effect treatment approach.
Jinglin Tian +3 more
doaj +4 more sources
Near-infrared photoimmunotherapy for osteosarcoma targeting epidermal growth factor receptor [PDF]
Translational OncologyOsteosarcoma is the most common bone tumor, and it possesses high metastatic propensity. Although systemic chemotherapy has improved its prognosis, improvements in survival rates have stalled in recent years.
Motofumi Suzuki +2 more
doaj +4 more sources
Near infrared photoimmunotherapy for cancers: A translational perspective [PDF]
EBioMedicine, 2021 Near-infrared photoimmunotherapy (NIR-PIT) is a newly-developed, highly-selective cancer treatment, which utilizes a monoclonal antibody conjugated to a photoabsorbing dye, IRDye700DX (IR700).
Yasuhiro Maruoka +3 more
doaj +3 more sources
In Vitro Comparative Study of Near-Infrared Photoimmunotherapy and Photodynamic Therapy [PDF]
Cancers, 2023 Near-infrared photoimmunotherapy (NIR-PIT) is a new phototherapy that utilizes a monoclonal antibody (mAb) against cancer antigens and a phthalocyanine dye, IRDye700DX (IR700) conjugate (mAb-IR700). Photodynamic therapy (PDT) is a combination therapy that utilizes photoreactive agents and light irradiation as well as NIR-PIT.
Makoto Shibutani, Nobuhiko Onda
exaly +4 more sources
Recent advances in near-infrared dye conjugates for near-infrared photoimmunotherapy (NIR-PIT): enhancing therapeutic efficacy and immune mechanisms [PDF]
RSC Chemical BiologyNear-infrared photoimmunotherapy (NIR-PIT) is an innovative cancer treatment modality that was approved in Japan in 2020 for the treatment of unresectable locally advanced or locally recurrent head and neck cancer.
Yoshikazu Fuse +4 more
doaj +2 more sources
NEAR-INFRARED PHOTOIMMUNOTHERAPY TARGETING OF CANCER-ASSOCIATED FIBROBLASTS
, 2023 Cancer-associated fibroblasts (CAFs) constitute a prominent cellular component of the tumor stroma, representing a heterogeneous group of activated fibroblasts.
Glabman, Raisa A
openaire +2 more sources
Expanding the application of cancer near-infrared photoimmunotherapy [PDF]
EBioMedicine, 2021 Hisataka Kobayashi
doaj +3 more sources
Biomedicines, 2022 Near-infrared photoimmunotherapy (NIR-PIT) is a newly developed and promising therapy that specifically destroys target cells by irradiating antibody-photo-absorber conjugates (APCs) with NIR light.
Hideyuki Furumoto +5 more
doaj +3 more sources
Enhancement of drug delivery through fibroblast activation protein–targeted near-infrared photoimmunotherapy [PDF]
JCI InsightThe tumor microenvironment plays a key role in cancer progression and therapy resistance, with cancer-associated fibroblasts (CAFs) contributing to desmoplasia, extracellular matrix (ECM) remodeling, and elevated interstitial fluid pressure, all of which
Seitaro Nishimura +21 more
doaj +2 more sources