Results 21 to 30 of about 2,604,331 (176)

EpCAM-targeted near-infrared photoimmunotherapy (NIR-PIT) for the treatment of breast cancer [PDF]

Annals of Medicine
Background Near-infrared photoimmunotherapy (NIR-PIT) is a targeted cancer treatment that uses antibody-IR700 conjugates and selectively destroys cancer cells expressing a target antigen when exposed to near-infrared (NIR) light.
Aki Furusawa, Seiichiro Takao, Motofumi Suzuki, Makoto Kano, Hiroshi Yamamoto, Miyu Kano, Peter Choyke, Hisataka Kobayashi   +7 more
doaj   +2 more sources

Near-Infrared Photoimmunotherapy Combined with CTLA4 Checkpoint Blockade in Syngeneic Mouse Cancer Models

Vaccines, 2020
Near infrared photoimmunotherapy (NIR-PIT) is a newly developed and highly selective cancer treatment that induces necrotic/immunogenic cell death. It employs a monoclonal antibody (mAb) conjugated to a photo-absorber dye, IRDye700DX, which is activated ...
Yasuhiro Maruoka, Aki Furusawa, Ryuhei Okada, Fuyuki Inagaki, Daiki Fujimura, Hiroaki Wakiyama, Takuya Kato, Tadanobu Nagaya, Peter L. Choyke, Hisataka Kobayashi   +9 more
doaj   +3 more sources

Near-infrared photoimmunotherapy using antiGD2 antibody for neuroblastoma and osteosarcoma

EJC Paediatric Oncology
Introduction: Near-infrared photoimmunotherapy (NIR-PIT) is a novel cancer therapy that specifically targets cancer cells. In NIR-PIT, antibody-photo-absorber-conjugates (APCs), specific for cancer antigens, target cancer cells.
Jimei Zhao, Kohei Nakajima, Masahiro Ueki, Yukayo Terashita, Shinsuke Hirabayashi, Yuko Cho, Mikako Ogawa, Atsushi Manabe   +7 more
doaj   +3 more sources

Near-infrared photoimmunotherapy for recurrent cancer at the base of the tongue

Photodiagnosis and Photodynamic Therapy
Near-infrared photoimmunotherapy (NIR-PIT) is a novel therapeutic approach that targets epidermal growth factor receptor (EGFR). In NIR-PIT, administration of cetuximab sarotalocan sodium is followed by laser irradiation of the affected area, which ...
Takuma Makino, Asami Nishikori, Yasuharu Sato, Yuto Naoi, Junya Matsumoto, Shohei Fujimoto, Mizuo Ando   +6 more
doaj   +3 more sources

Targeted Elimination of Influenza Virus and Infected Cells with Near-Infrared Antiviral Photoimmunotherapy (NIR-AVPIT)

Pharmaceutics
Background: Seasonal influenza causes significant morbidity and mortality each year. Since viruses can easily acquire drug-resistant mutations, it is necessary to develop new antiviral strategies with different targets.
Terumi Mizukoshi, Koichiro Tateishi, Mizuki Tokusanai, Yoshiyuki Yoshinaka, Aisaku Yamamoto, Naoki Yamamoto, Norio Yamamoto   +6 more
doaj   +2 more sources

Tissue factor targeted near-infrared photoimmunotherapy: a versatile therapeutic approach for malignancies [PDF]

Cancer Immunology, Immunotherapy
Tissue factor (TF) is a cell surface protein that plays a role in blood clotting but is also commonly expressed in many cancers. Recent research implicated TF in cancer proliferation, metastasis, angiogenesis, and immune escape.
Seiichiro Takao, Hiroshi Fukushima, Aki Furusawa, Takuya Kato, Shuhei Okuyama, Makoto Kano, Hiroshi Yamamoto, Motofumi Suzuki, Miyu Kano, Peter L. Choyke, Hisataka Kobayashi   +10 more
doaj   +2 more sources

Combined CD25-targeted near infrared photoimmunotherapy (NIR-PIT) and intratumor IL-15 enhance the effectiveness of anti-PD-1 immunotherapy [PDF]

Cancer Immunology, Immunotherapy
Immunotherapies aimed at enhancing anti-cancer immunity are now in wide clinical use. For instance, anti-programmed cell death protein 1 (PD-1) monoclonal antibody (mAb) therapy has demonstrated clinical efficacy in many tumor types, but overall, only a ...
Makoto Kano, Aki Furusawa, Hiroshi Fukushima, Seiichiro Takao, Shuhei Okuyama, Hiroshi Yamamoto, Motofumi Suzuki, Miyu Kano, Ko Kitamura, Peter L. Choyke, Hisataka Kobayashi   +10 more
doaj   +2 more sources

Portable microcontroller-based instrument for near-infrared spectroscopy [PDF]

, 2000
Near Infrared Spectroscopy (NIRS) can be employed to noninvasively and continuously measure in-vivo local changes in haemodynamics and oxygenation of human tissues.
Giardini, Mario Ettore, Lago, Paolo, Corti, Mario, Gelmetti, Andrea   +3 more
core   +4 more sources

Near-infrared spectra of aqueous glucose solutions [PDF]

, 2022
Infrared spectroscopy is widely utilized in the scientific community for chemical characterization of materials. Near-infrared spectroscopy relies on spectral measurements between 900 and 2,500 nm.
Lee, Tse-Ang, Peng, Jessie, Hutter, Tanya   +2 more
core   +1 more source

Microcontroller-based digital front-end for near-infrared spectroscopy [PDF]

, 2000
Near Infrared Spectroscopy (NIRS) can be employed to noninvasively and continuously measure in-vivo local changes in haemodynamics and oxygenation of human tissues.
Andrea Gelmetti, Lago, P, Corti, M, Danese, G, Guizzetti, Giovanni G., Danese, Giovanni, Corti, Mario, Paolo Lago, Gelmetti, A, Giovanni Danese, Giardini, Mario Ettore, Lago, Paolo, Giardini, M E, Guizzetti, G G, Mario Corti, Gelmetti, Andrea, Mario E. Giardini, Giovanni G. Guizzetti   +17 more
core   +4 more sources