Non-apoptotic Regulated Cell Death Mechanisms in Sepsis and their Therapeutic Potential. [PDF]
InflammationMitre AO +5 more
europepmc +1 more source
Clinical and Translational Medicine, Volume 16, Issue 3, March 2026.NINJ1 mediates PMR in cardiovascular cell death, releasing DAMPs that amplify vascular inflammation. Dual NINJ1 paradox: membrane‐bound form drives endothelial NF‐κB/CXCL‐8 inflammation while soluble form provides atheroprotection. Pericyte NINJ1 regulates the critical balance between angiogenic sprouting and vessel maturation in ischaemic tissues ...
Muhammad Mamunur Rashid Mahib
wiley +1 more source
Targeted Induction of Cancer Cell Necroptosis Potentiates Anti-PD-1 Immunotherapy via CD80 Activation. [PDF]
Int J Biol SciZhang X +7 more
europepmc +1 more source
Dihydromyricetin Regulates PANoptosis to Protect Salmonella Typhimurium‐Infected Weaned Piglets
Food Frontiers, Volume 7, Issue 2, March 2026.After DHM pretreatment, piglets were subjected to Salmonella infection. Serum and ileocecal samples from the piglets were collected for TUNEL assay, Western blotting analysis, and metabolomics analysis. The results collectively indicated that DHM could protect piglets from Salmonella infection.
Tingting Xiao +6 more
wiley +1 more source
Ibrain, Volume 12, Issue 1, Page 65-85, Spring 2026.Chemotherapy‐induced peripheral neuropathy (CIPN) remains a major clinical challenge, with central sensitization considered an important pathological mechanism in its occurrence and persistence. This review focuses on spinal astrocytes and microglia, systematically summarizing the pathological mechanisms of spinal glial cells involved in CIPN caused by
Long Gu, Song Cao, Yonghuai Feng
wiley +1 more source
Journal of Intelligent Medicine, Volume 3, Issue 1, Page 47-68, March 2026.Abstract The isoproterenol‐induced myocardial infarction model is a well‐established experimental approach for studying cardiac injury and testing potential protective treatments. By overstimulating beta‐adrenergic receptors, this model closely reproduces key features of human heart attacks, including oxidative damage, calcium imbalance, inflammatory ...
Bushra Imran +5 more
wiley +1 more source
Tilianin Attenuates Myocardial Ischemia-Reperfusion Injury by Targeting RIP3-Mediated Necroptosis. [PDF]
Pharmaceuticals (Basel)Zheng R +9 more
europepmc +1 more source
MMP14-Dependent Activation of TGF-β Signaling Enhances Malignancies via Promoting Necroptosis in Glioblastoma. [PDF]
FASEB JZhou H +7 more
europepmc +1 more source
Multifacet Roles of Cellular Senescence in Cancer: Mechanisms and Therapeutic Implications
MedComm – Oncology, Volume 5, Issue 1, March 2026.Cellular senescence shapes tumor progression through both antitumor and protumor mechanisms. Senescence triggered by telomere shortening restricts malignant transformation and limits tumor cell proliferation, while the senescence‐associated secretory phenotype (SASP) secretion enhances antitumor immunity by activating cytotoxic T cells.
Huajie Mao +5 more
wiley +1 more source
Looking at the fraction with Annexin V⁺ and propidium iodide⁺: insights into cell death types from preclinical studies in solid and haematological cancers. [PDF]
ApoptosisHassan SN, Ahmad F.
europepmc +1 more source