Results 61 to 70 of about 47,289 (162)
Genes and DiseasesIn recent years, research has highlighted that necroptosis plays a significant role in various diseases, suggesting that studying the pathways of necroptosis may offer novel avenues for developing treatments for these conditions.
Tong Li +7 more
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Cells, 2019 Necroptosis, or regulated necrosis, is an important type of programmed cell death in addition to apoptosis. Necroptosis induction leads to cell membrane disruption, inflammation and vascularization.
Jing Chen +3 more
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Breast Cancer Research, 2023 Necroptosis is a form of regulated necrosis and is executed by MLKL when MLKL is engaged in triggering the rupture of cell plasma membrane. MLKL activation also leads to the protease, ADAMs-mediated ectodomain shedding of cell surface proteins of ...
Zhaoshan Liu +5 more
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Necroptosis inhibitors supress HC damage.
, 2021 (A, B) Necroptosis inhibitors necrostatin-1 (A) (IHC and OHC: P B) (IHC: P P P C) p-Mlkl (green) expression in HCs induced by TMEV infection was inhibited by necrostatin-1.
Hidenori Suzuki (189652) +15 more
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Necroptosis takes place in human immunodeficiency virus type-1 (HIV-1)-infected CD4+ T lymphocytes.
PLoS ONE, 2014 Human immunodeficiency virus type 1 (HIV-1) infection is characterized by progressive depletion of CD4+ T lymphocytes and dysfunction of the immune system.
Ting Pan +11 more
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DataSheet_1_Tumor necrosis factor is a necroptosis-associated alarmin.docx
, 2022 Necroptosis is a form of regulated cell death that can occur downstream of several immune pathways. While previous studies have shown that dysregulated necroptosis can lead to strong inflammatory responses, little is known about the identity of the ...
Gunnar Kuut (12527206) +5 more
core +1 more source
Opposing regulation of the K63-linked polyubiquitination of RIPK3 by SMURF1 and USP5 in necroptosis
Nature CommunicationsReceptor-interacting protein kinase 3 (RIPK3), a key regulator of necroptosis, is modulated by ubiquitination through various E3 ligases and deubiquitinases.
Chi Hyun Hwang +9 more
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Autophagy, selective autophagy, and necroptosis in COPD
, 2018 Kenji Mizumura, Shuichiro Maruoka, Tetsuo Shimizu, Yasuhiro Gon Division of Respiratory Medicine, Department of Internal Medicine, Nihon University School of Medicine, Tokyo, Japan Abstract: COPD is characterized by persistent respiratory symptoms and ...
Maruoka S, Gon Y, Shimizu T, Mizumura K
core
Necroptosis in Cholangiocarcinoma [PDF]
, 2020 Necroptosis is a type of regulated cell death that is increasingly being recognized as a relevant pathway in different pathological conditions. Necroptosis can occur in response to multiple stimuli, is triggered by the activation of death receptors, and ...
Luca Fabris +10 more
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Cell Death and Disease, 2020 Intestinal ischemia reperfusion (I/R) injury is the important pathogenesis for acute intestinal barrier disruption. The STING signaling is associated with gut homeostasis and barrier integrity.
Xufei Zhang +9 more
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