Results 61 to 70 of about 43,311 (200)

Image5_Characterizing the prognostic and therapeutic value of necroptosis in sarcoma based on necroptosis subtypes.JPEG

open access: yes, 2022
Necroptosis, a type of necrotic cell death independent of caspase regulation, is mainly mediated by receptor interacting serine/threonine kinase 1 (RIPK1), receptor interacting serine/threonine kinase 3 (RIPK3) and mixed lineage kinase domain-like (MLKL).
Shuo Zheng (458517)   +5 more
core   +1 more source

Table1_Characterizing the prognostic and therapeutic value of necroptosis in sarcoma based on necroptosis subtypes.DOC

open access: yes, 2022
Necroptosis, a type of necrotic cell death independent of caspase regulation, is mainly mediated by receptor interacting serine/threonine kinase 1 (RIPK1), receptor interacting serine/threonine kinase 3 (RIPK3) and mixed lineage kinase domain-like (MLKL).
Shuo Zheng (458517)   +5 more
core   +1 more source

Image4_Characterizing the prognostic and therapeutic value of necroptosis in sarcoma based on necroptosis subtypes.JPEG

open access: yes, 2022
Necroptosis, a type of necrotic cell death independent of caspase regulation, is mainly mediated by receptor interacting serine/threonine kinase 1 (RIPK1), receptor interacting serine/threonine kinase 3 (RIPK3) and mixed lineage kinase domain-like (MLKL).
Shuo Zheng (458517)   +5 more
core   +1 more source

Necroptosis is associated with Rab27‐independent expulsion of extracellular vesicles containing RIPK3 and MLKL

open access: yesJournal of Extracellular Vesicles, 2022
Extracellular vesicle (EV) secretion is an important mechanism used by cells to release biomolecules. A common necroptosis effector—mixed lineage kinase domain like (MLKL)—was recently found to participate in the biogenesis of small and large EVs ...
Kartik Gupta   +14 more
doaj   +1 more source

Necroptosis: Molecular Signalling and Translational Implications [PDF]

open access: yes, 2014
Necroptosis is a form of programmed necrosis whose molecular players are partially shared with apoptotic cell death. Here we summarize what is known about molecular signalling of necroptosis, particularly focusing on fine tuning of FLIP and IAP proteins
Donatella Starace   +9 more
core   +1 more source

Role of necroptosis and immune infiltration in essential thrombocytosis

open access: yesHereditas
Background Necroptosis, a recently identified form of programmed cell death involved in the pathogenesis of a variety of tumor and non-tumor diseases. Nevertheless, the function of necroptosis in essential thrombocytosis (ET) remains unclear, which is a ...
Guangming Li, Ying Guo, Yuanyuan Zhang
doaj   +1 more source

Systematic analysis of the necroptosis index in pan-cancer and classification in discriminating the prognosis and immunotherapy responses of 1716 glioma patients

open access: yesFrontiers in Pharmacology, 2023
Necroptosis is a programmed form of necrotic cell death that serves as a host gatekeeper for defense against invasion by certain pathogens. Previous studies have uncovered the essential role of necroptosis in tumor progression and implied the potential ...
Shuai Ma   +18 more
doaj   +1 more source

The Emerging Roles of Pyroptosis, Necroptosis, and Ferroptosis in Non-Malignant Dermatoses: A Review

open access: yes, 2023
Yan Teng,1 Danfeng Xu,1 Xianhong Yang,1 Hui Tang,2 Xiaohua Tao,1 Yibin Fan,1,* Yang Ding1,* 1Center for Plastic & Reconstructive Surgery, Department of Dermatology, Zhejiang Provincial People’s Hospital, Affiliated People’s Hospital of Hangzhou ...
Yang X   +6 more
core  

Table2_Characterizing the prognostic and therapeutic value of necroptosis in sarcoma based on necroptosis subtypes.XLSX

open access: yes, 2022
Necroptosis, a type of necrotic cell death independent of caspase regulation, is mainly mediated by receptor interacting serine/threonine kinase 1 (RIPK1), receptor interacting serine/threonine kinase 3 (RIPK3) and mixed lineage kinase domain-like (MLKL).
Shuo Zheng (458517)   +5 more
core   +1 more source

Proteolytic control of necroptosis [PDF]

open access: yes, 2018
The present works’ aim has been to gain further insights into the proteolytic mechanisms present in necroptosis via multiple routes: investigating an in-vivo model for necroptosis in DSS-induced colitis in mice with an extremely reduced expression of the
Fuchslocher Chico, Johaiber Ilich
core   +1 more source

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