Results 71 to 80 of about 342 (145)

Executive summary: Japanese guidelines for atopic dermatitis (ADGL) 2024

Allergology International
This is an abridged edition of English version of the Clinical Practice Guidelines for the Management of Atopic Dermatitis 2024. Atopic dermatitis (AD) is a disease characterized by relapsing eczema with pruritus as a primary lesion.
Hidehisa Saeki, Yukihiro Ohya, Hirokazu Arakawa, Susumu Ichiyama, Toshio Katsunuma, Norito Katoh, Akio Tanaka, Hideaki Tanizaki, Yuichiro Tsunemi, Takeshi Nakahara, Mizuho Nagao, Masami Narita, Michihiro Hide, Takao Fujisawa, Masaki Futamura, Koji Masuda, Tomoyo Matsubara, Hiroyuki Murota, Kiwako Yamamoto-Hanada, Junichi Furuta   +19 more
doaj   +1 more source

Efficacy and safety of nemolizumab versus placebo for the treatment of atopic dermatitis

Eczema is one of the most common skin diseases and affecting approximately 10% of the population. Eczema which is now known as dermatitis, is due to an inflammatory process in the upper skin layers and comes in different variants.
Garp, Lisa
core   +3 more sources

Biologic and Small Molecule Therapy in Atopic Dermatitis

Biomedicines
Atopic dermatitis is a chronic inflammatory dermatosis characterized by pruritic, scaly, erythematous lesions. Its incidence varies but is estimated to be approximately 20% in children and between 7 and 14% in adults, with variation amongst countries. It
Mahek Shergill, Barinder Bajwa, Orhan Yilmaz, Karishma Tailor, Naila Bouadi, Ilya Mukovozov   +5 more
doaj   +1 more source

Role of the Pruritic Cytokine IL-31 in Autoimmune Skin Diseases

Frontiers in Immunology, 2019
Many autoimmune skin diseases, such as bullous pemphigoid (BP), psoriasis and certain types of chronic urticaria, are associated with intensive pruritus.
Bernhard F. Gibbs, Nikolaos Patsinakidis, Ulrike Raap   +2 more
doaj   +1 more source

Nemolizumab as an Alternative Therapeutic Option for Indolent Systemic Mastocytosis

Cureus
Indolent systemic mastocytosis (ISM) is a clonal mast cell disorder characterized by recurrent symptoms that can persist despite treatment with antihistamines, leukotriene antagonists, and mast cell stabilizers. Treatment options are limited when symptoms remain refractory, and avapritinib is contraindicated or declined.
Minbaeva, Sezim, Tyring, Stephen K
openaire   +2 more sources

Redrawing the Map in Prurigo Nodularis: From Conventional Approaches to Targeted Biologics

Dermatologic Therapy
Background Prurigo nodularis (PN) is a chronic, neuroimmune‐mediated dermatosis characterized by intense pruritus and nodular lesions that severely impair patient quality of life.
Göknur Kalkan
doaj   +1 more source

Direct randomized evidence for systemic targeted therapies in prurigo nodularis: a systematic review and meta-analysis

Frontiers in Medicine
BackgroundSystemic targeted therapies are reshaping treatment for prurigo nodularis (PN), but the timing of clinically meaningful benefits and the strength of supporting evidence remain unclear.
Yue Yu, Siqi Li, Weiwen Chen, Xinsheng Chen   +3 more
doaj   +1 more source

Safety and efficacy of nemolizumab for atopic dermatitis up to 2 years in open-label extension study

Background: Atopic dermatitis (AD) is a common, chronic, relapsing, pruritic, neuroimmune skin disease, requiring long-term symptom control. Objectives: The ARCADIA long-term extension (LTE) study evaluates nemolizumab safety and efficacy in ≥12-year-old
Alpizar, Sady, Gold, Linda Stein, Galus, Ryszard, Maintz, Laura, Sidbury, Robert, Papp, Kim A., Augustin, Matthias, Barber, Kirk, Kaszuba, Andrzej, Laquer, Vivian, Zirwas, Matthew, Reich, Adam, De Bruin-Weller, Marjolein S., Trullenque, Gretel, Drahos, Agnes, Cheong, Soo Yeon, Thaçi, Diamant, Ulianov, Liliana, Silverberg, Jonathan I., Peris, Ketty, Infection & Immunity, Son, Sang Wook, Tauber, Marie, Nahm, Walter K., MS Dermatologie/Allergologie, Piketty, Christophe, Ryzhkova, Anna   +26 more
core   +3 more sources

Efficacy and Safety of Nemolizumab for Treatment of Adult Atopic Dermatitis [PDF]

Journal of Investigational Allergy and Clinical Immunology, 2021
Freemantle, N, Piketty, C
openaire   +3 more sources

Emerging Therapies in the Treatment of Prurigo Nodularis: Biological Therapy and Systematic Review of Literature

Dermatology and Therapy
Introduction Prurigo nodularis (PN) is a chronic, intensely pruritic dermatosis characterized by hyperkeratotic nodules and a persistent itch–scratch cycle.
Gaetano Licata, Mariachiara Arisi, Caterina Mariarosaria Giorgio, Cesare Ariasi, Cesare Tomasi, Simone Soglia, Sara Mezzana, Benedetta Galli, Grazia Linda Artelli, Mariateresa Rossi, Cecilia Catapano   +10 more
doaj   +1 more source