Results 81 to 90 of about 1,056 (174)

A Case of Erythema Multiforme Following the Administration of Nemolizumab

Cureus
Prurigo nodularis (PN) is a chronic inflammatory skin disorder characterized by intensely pruritic nodules. The pathogenesis of PN involves immune dysregulation, with a predominance of T helper (Th2)-type inflammation, including interleukin (IL)-4, IL-5, IL-13, and IL-31. Nemolizumab, an IL-31 receptor A inhibitor, was newly approved for PN in 2024. We
Mima, Yoshihito, Ohtsuka, Tsutomu
openaire   +2 more sources

Table_2_Safety and Efficacy of Nemolizumab for Atopic Dermatitis With Pruritus: A Systematic Review and Meta-Regression Analysis of Randomized Controlled Trials.docx

, 2022
BackgroundNemolizumab is deemed as a promising drug for atopic dermatitis (AD) patients with pruritus.ObjectiveThis study aimed to evaluate the efficacy of nemolizumab in treating patients with AD and the association between the dosage or regimen of ...
Fengxia Hu (5745692), Xiaojing Kang (3931046), Maoli Dan (12459273), Qian Wang (32718), Yongzhen Hong (12459282), Junqin Liang (12459270), Yingbing Sang (12459276), Kailibinuer Abulikemu (12459279)   +7 more
core   +1 more source

Executive summary: Japanese guidelines for atopic dermatitis (ADGL) 2024

Allergology International
This is an abridged edition of English version of the Clinical Practice Guidelines for the Management of Atopic Dermatitis 2024. Atopic dermatitis (AD) is a disease characterized by relapsing eczema with pruritus as a primary lesion.
Hidehisa Saeki, Yukihiro Ohya, Hirokazu Arakawa, Susumu Ichiyama, Toshio Katsunuma, Norito Katoh, Akio Tanaka, Hideaki Tanizaki, Yuichiro Tsunemi, Takeshi Nakahara, Mizuho Nagao, Masami Narita, Michihiro Hide, Takao Fujisawa, Masaki Futamura, Koji Masuda, Tomoyo Matsubara, Hiroyuki Murota, Kiwako Yamamoto-Hanada, Junichi Furuta   +19 more
doaj   +1 more source

Image_1_Safety and Efficacy of Nemolizumab for Atopic Dermatitis With Pruritus: A Systematic Review and Meta-Regression Analysis of Randomized Controlled Trials.tif

, 2022
BackgroundNemolizumab is deemed as a promising drug for atopic dermatitis (AD) patients with pruritus.ObjectiveThis study aimed to evaluate the efficacy of nemolizumab in treating patients with AD and the association between the dosage or regimen of ...
Fengxia Hu (5745692), Xiaojing Kang (3931046), Maoli Dan (12459273), Qian Wang (32718), Yongzhen Hong (12459282), Junqin Liang (12459270), Yingbing Sang (12459276), Kailibinuer Abulikemu (12459279)   +7 more
core   +1 more source

Biologic and Small Molecule Therapy in Atopic Dermatitis

Biomedicines
Atopic dermatitis is a chronic inflammatory dermatosis characterized by pruritic, scaly, erythematous lesions. Its incidence varies but is estimated to be approximately 20% in children and between 7 and 14% in adults, with variation amongst countries. It
Mahek Shergill, Barinder Bajwa, Orhan Yilmaz, Karishma Tailor, Naila Bouadi, Ilya Mukovozov   +5 more
doaj   +1 more source

Role of the Pruritic Cytokine IL-31 in Autoimmune Skin Diseases

Frontiers in Immunology, 2019
Many autoimmune skin diseases, such as bullous pemphigoid (BP), psoriasis and certain types of chronic urticaria, are associated with intensive pruritus.
Bernhard F. Gibbs, Nikolaos Patsinakidis, Ulrike Raap   +2 more
doaj   +1 more source

Efficacy and Safety of Nemolizumab for Treatment of Adult Atopic Dermatitis [PDF]

Journal of Investigational Allergy and Clinical Immunology, 2021
Freemantle, N, Piketty, C
openaire   +3 more sources

The efficacy and safety of nemolizumab in patients with prurigo nodularis: A systematic review and meta-analysis of randomized controlled trials

We systematically review the efficacy and safety of nemolizumab among existing randomized, double-blinded, and placebo-controlled clinical trials of nemolizumab for the treatment of ...
Titou, Hicham
core   +1 more source

Emerging Therapies in the Treatment of Prurigo Nodularis: Biological Therapy and Systematic Review of Literature

Dermatology and Therapy
Introduction Prurigo nodularis (PN) is a chronic, intensely pruritic dermatosis characterized by hyperkeratotic nodules and a persistent itch–scratch cycle.
Gaetano Licata, Mariachiara Arisi, Caterina Mariarosaria Giorgio, Cesare Ariasi, Cesare Tomasi, Simone Soglia, Sara Mezzana, Benedetta Galli, Grazia Linda Artelli, Mariateresa Rossi, Cecilia Catapano   +10 more
doaj   +1 more source

Efficacy and Safety of Nemolizumab in Patients With Moderate to Severe Prurigo Nodularis: The OLYMPIA 1 Randomized Clinical Phase 3 Trial

Prurigo nodularis (PN) is a chronic and debilitating skin condition, characterized by intense itch with multiple nodular lesions. Nemolizumab demonstrated significant improvements in itch and skin nodules in adults with moderate to severe PN in a ...
Naldi, Luigi, Augustin, Matthias, Metelitsa, Andrei, Legat, Franz J, Fargnoli, Maria Concetta, Fage, Simon, Wollenberg, Andreas, Reich, Adam, Piketty, Christophe, Ständer, Sonja, Paul, Carle, Metz, Martin, Sundaram, Hema, Skov, Lone, Simon, Dagmar, Weisshaar, Elke, Sofen, Howard, Tsianakas, Athanasios, Jabbar-Lopez, Zarif K, Pink, Andrew, Korman, Neil J, Micali, Giuseppe, Kwatra, Shawn G, Chen, Xiaoxiao, OLYMPIA 1 Investigators, Yosipovitch, Gil, Homey, Bernhard   +26 more
core   +1 more source