Epilepsy in emerging adulthood: Clinical, psychosocial, and surgical challenges
Abstract Objective Emerging adulthood (EAs; ages 19–29 years) is a unique developmental stage marked by major psychological, social, and occupational transitions. We sought to characterize the clinical, psychosocial, and surgical features of epilepsy in emerging adulthood, considering both current age and age at epilepsy onset.
Graham A. McLeod +26 more
wiley +1 more source
An Introduction to Predictive Processing Models of Perception and Decision‐Making
Abstract The predictive processing framework includes a broad set of ideas, which might be articulated and developed in a variety of ways, concerning how the brain may leverage predictive models when implementing perception, cognition, decision‐making, and motor control.
Mark Sprevak, Ryan Smith
wiley +1 more source
Length of the Neurogenic Period-A Key Determinant for the Generation of Upper-Layer Neurons During Neocortex Development and Evolution. [PDF]
Stepien BK, Vaid S, Huttner WB.
europepmc +1 more source
Dual role of spreading depolarization in an epileptic focus
Abstract Objective Spreading depolarizations (SDs) are often associated with epileptic discharges. Although SDs are traditionally thought to contribute to postictal depression and termination of epileptic discharges, seizures may also occur during SDs or may even follow SDs, suggesting that interactions between SD and seizures are more complex.
Daria Vinokurova +3 more
wiley +1 more source
Longitudinal tracking of neuronal activity from the same cells in the developing brain using Track2p
Understanding cortical circuit development requires tracking neuronal activity across days in the growing brain. While in vivo calcium imaging now enables such longitudinal studies, automated tools for reliably tracking large populations of neurons ...
Jure Majnik +6 more
doaj +1 more source
The case for a relationship between human memory, hippocampus and corpus callosum [PDF]
Unilateral brain damage which includes the hippocampus leads to memory impairments consistent with hemispheric specialization on the same side. Damage to the corpus callosum, the major connecting pathway between the left and right hemispheres, also ...
Zaidel, Dahlia W.
core
Constructing Circuits: Neurogenesis and Migration in the Developing Neocortex [PDF]
Summary: Our knowledge of the proliferation, migration, and differentiation of neurons has changed dramatically over the last 10 years. Whereas traditionally it was thought that glial and neuronal cells were separate cell lines with different lineages, we now know that this is not true.
openaire +2 more sources
WONOEP XVII appraisal: The role of the extracellular matrix in epilepsy
Abstract The extracellular matrix (ECM) is composed of proteoglycans and glycoproteins that regulate the external environment surrounding neurons, glia, and the vascular system. The ECM is vital for maintaining the structure and function of the brain and also acts as a reservoir for various signaling molecules and neurotransmitters, modulating synaptic
Eleonora Lugara +7 more
wiley +1 more source
The Laminar Architecture of Visual Cortex and Image Processing Technology [PDF]
The mammalian neocortex is organized into layers which include circuits that form functional columns in cortical maps. A major unsolved problem concerns how bottom-up, top-down, and horizontal interactions are organized within cortical layers to generate
Grossberg, Stephen
core +1 more source
Abstract Objective To clinically validate the contribution of a custom‐built EEG wearable device (waEEG) compared to a full 10–20 electrode array ambulatory EEG (aEEG) for screening epilepsy cases in patients with suspected temporal lobe epilepsy (TLE) but negative routine EEGs. Methods Patients (aged 16–91 years) with clinically suspected TLE who were
Daniel Filipe Borges +4 more
wiley +1 more source

