Results 171 to 180 of about 4,213 (269)

Mammalian TatD DNase domain containing 1 (TATDN1) is a proteostasis‐responsive gene with roles in ventricular structure and neuromuscular function

The FEBS Journal, EarlyView.
Twin‐arginine translocation D (TatD) homologs are found across all kingdoms, with debated roles in DNA degradation and protein quality control in unicellular organisms. We characterize TATDN1, the mammalian TatD orthologue, as a proteostatic stress‐responsive cytosolic protein dispensable for DNA degradation.
Gisel Barés, Aida Beà, Anna Sancho‐Balsells, Juan G Valero, David Aluja, Javier Inserte, Sandra García‐Carpi, Elisabet Miró‐Casas, Sara Borràs‐Pernas, Sara Hernández, Ana Martínez‐Val, Jesper V Olsen, Francesc Tebar, Xavier Cañas, Joan X. Comella, Patricia Pérez‐Galán, Marisol Ruiz‐Meana, Albert Giralt, Marta Llovera, Daniel Sanchis   +19 more
wiley   +1 more source

Towardin vitro-to-in vivotranslation of monoclonal antibody pharmacokinetics: Application of a neonatal Fc receptor-mediated transcytosis assay to understand the interplaying clearance mechanisms [PDF]

, 2017
Claudia A. Castro Jaramillo, Sara Belli, Anne‐Christine Cascais, Sherri Dudal, Martin R. Edelmann, Markus Haak, Marie-Elise Brun, Michael B. Otteneder, Mohammed Ullah, Christoph Funk, Franz Schuler, Silke Simon   +11 more
openalex   +1 more source

Hidradenitis Suppurativa Treatment During Pregnancy and Lactation: Navigating Challenges

International Journal of Dermatology, EarlyView.
ABSTRACT Hidradenitis suppurativa (HS), or acne inversa, is a chronic inflammatory skin condition primarily affecting skin folds such as the axilla, groins, and the inframammary, perineal, and perianal regions. It is characterized by painful abscesses, sinus tracts, and scarring.
Laşin Özbek, Mustafa Güldan, Erkan Alpsoy, Seçil Vural   +3 more
wiley   +1 more source

How the controller is controlled – neonatal Fc receptor expression and immunoglobulin G homeostasis

, 2006
Shuo‐Wang Qiao, Wayne I. Lencer, Richard S. Blumberg   +2 more
openalex   +2 more sources

Child and Family Centred Care: A Three‐Phased Principle‐Based Concept Analysis

Journal of Advanced Nursing, EarlyView.
ABSTRACT Introduction Despite a growing multidisciplinary interest in the Child and Family Centred Care approach, its meaning remains unclear in extant literature. It is, therefore, crucial to explore, analyse, describe, and clarify the concept of the Child and Family Centred Care approach and its associated terms. Method A three‐phased principle‐based
Maggie Zgambo, Julie Blamires, Mandie Foster, Mohammad Al‐Motlaq, Therese A. O'Sullivan, Davina Houghton, Evalotte Mörelius, the International Network for Child and Family Centred Care   +7 more
wiley   +1 more source

In vivo depletion of serum IgG by an affibody molecule binding the neonatal Fc receptor [PDF]

, 2018
Johan Seijsing, Shengze Yu, Fredrik Y. Frejd, Ingmarie Höidén‐Guthenberg, Torbjörn Gräslund   +4 more
openalex   +1 more source

The Murine Neonatal Fc Receptor Is Required for Transport of Immunization-Induced C. difficile-Specific IgG to the Gut and Protection against Disease but Does Not Affect Disease Susceptibility

, 2021
Souwelimatou Amadou Amani, Gillian A. Lang, Jimmy D. Ballard, Mark L. Lang   +3 more
openalex   +2 more sources

The neonatal Fc receptor: Key to homeostasic control of IgG and IgG-related biopharmaceuticals [PDF]

, 2019
William M. Baldwin, Anna Valujskikh, Robert L. Fairchild   +2 more
openalex   +1 more source

Development of Paediatric‐Friendly Care Assessment Scale in Emergency Department: A Cross‐Sectional Study

Journal of Clinical Nursing, EarlyView.
ABSTRACT Aim To validate the psychometric properties of the Paediatric‐Friendly Care Assessment Scale in the Emergency Department (PFCAS‐ED) among clinical nurses. Design A cross‐sectional study. Methods A total of 463 emergency nurses participated in the study between May and September 2023.
Yen‐Ju Chen, Jao‐Shwann Liang, Frank Leigh Lu, Chiu‐Yueh Yang, Su‐Fen Cheng, Chieh‐Yu Liu, Chi‐Wen Chen   +6 more
wiley   +1 more source

Anti‐Ce in haemolytic disease of the foetus and newborn

Transfusion Medicine, EarlyView.
Abstract Objectives To report a delayed case of severe haemolytic disease of the foetus and newborn (HDFN) due to Anti‐Ce. Background HDFN due to maternal antibodies is potentially fatal. As a result, antibody levels and foetal anaemia are periodically monitored and risk assessed throughout pregnancy. HDFN due to Anti‐Ce is rare.
Rebecca O'Grady, Joan Fitzgerald, Jan Miletin, Carmen Regan, Fergus Guilfoyle, Edel Scally, Catherine Flynn   +6 more
wiley   +1 more source