Results 71 to 80 of about 1,820,535 (282)

Photodynamic effects on choroidal neovascularization and physiological choroid.

Investigative ophthalmology & visual science, 2002
To evaluate the effect of photodynamic therapy (PDT) on perfusion and vascular integrity of choroidal neovascularization (CNV) and collateral physiological choroid.In a prospective clinical trial, patients with subfoveal CNV were treated with PDT and verteporfin.
Ursula, Schmidt-Erfurth, Stephan, Michels, Irene, Barbazetto, Horst, Laqua   +3 more
openaire   +1 more source

Delivery of monocyte lineage cells in a biomimetic scaffold enhances tissue repair.

JCI Insight, 2017
The monocyte lineage is essential to normal wound healing. Macrophage inhibition or knockout in mice results in impaired wound healing through reduced neovascularization, granulation tissue formation, and reepithelialization. Numerous studies have either
Michael S. Hu, G. Walmsley, L. Barnes, K. Weiskopf, R. Rennert, D. Duscher, Michael Januszyk, Z. Maan, W. Hong, Alexander T. M. Cheung, Tripp Leavitt, Clement D. Marshall, R. C. Ransom, Samir Malhotra, A. Moore, Jayakumar Rajadas, H. Lorenz, I. Weissman, G. Gurtner, M. Longaker   +19 more
semanticscholar   +1 more source

Hybrid Nanofibers for Multimodal Accelerated Wound Healing

Advanced Healthcare Materials, EarlyView.
Fabrication of wound healing scaffolds based on biocompatible nanofibers. Nanofibers offering high surface area, flexibility, and biocompatibility significantly improved the healing outcome in vivo. Histological, immunological, and anti‐inflammatory markers are noticeably better in treated wounds.
Viraj P. Nirwan, Bence Bajusz, Norbert Fabók, Marina Rudan Dimlic, Jelena Budimir, Tshepang Mqatywa, Miklós Gyöngy, Márton Ferencz, Dorottya Kocsis, Olexandr Bondarenko, Mariia Rolduhina, Milena Lengyel, Istvan Antal, Rebecca Hengsbach, Franciska Erdő, Amir Fahmi   +15 more
wiley   +1 more source

Alterations of circulating endothelial cell and endothelial progenitor cell counts around the ovulation. [PDF]

, 2012
Context:Circulating endothelial cells (CECs) and progenitor cells (CEPs) have been intensively studied as a promising tool for treating ischemic diseases and monitoring cancer treatments, but how the menstrual cycle affects the variation in their counts ...
Chigusa, Yoshitsugu, Fujisawa, Noriyoshi, Fujita, Masatoshi, Fujiwara, Hiroshi, Kawaguchi-Sakita, Nobuko, Kawashima, Masahiro, Sato, Fumiaki, Tanaka, Sunao, Teramukai, Satoshi, Toi, Masakazu, Ueno, Takayuki, Yoshimura, Kenichi   +11 more
core   +1 more source

Intravitreal Anti-VEGF Drugs and Signals of Dementia and Parkinson-Like Events: Analysis of the VigiBase Database of Spontaneous Reports [PDF]

, 2020
Introduction: Since vascular endothelial growth factor (VEGF) regulates several aspects of the central nervous system, particularly in dopaminergic neurons, VEGF inhibitors may be linked to Parkinson-like events and dementia, or variants of these ...
Avery, Bergvall, Caballero, Campochiaro, Cutroneo, de Jong, De Rossi, Evans, Ferrara, Ferrara, Kumar, Lim, Lindquist, McColl, Meyer, Robinson, Sanchez, Sharma, Sheikh, Simó, Steen, Storkebaum, Sultana, Thulliez, Tian, Trifirò, Ueta, Wong, Yasuhara, Ylä-Herttuala, Zachary   +30 more
core   +4 more sources

Gene therapy knockdown of VEGFR2 in retinal endothelial cells to treat retinopathy

Angiogenesis, 2018
Inhibition of vascular endothelial growth factor (VEGF) in retinopathy of prematurity (ROP) raises concerns for premature infants because VEGF is essential for retinovascular development as well as neuronal and glial health.
Aaron B. Simmons, C. Bretz, Haibo Wang, Eric Kunz, Kassem Hajj, Carson D. Kennedy, Zhihong Yang, Thipparat Suwanmanee, T. Kafri, M. Hartnett   +9 more
semanticscholar   +1 more source

Tissue Hypoxia and Alterations in Microvascular Architecture Predict Glioblastoma Recurrence in Humans

Clinical Cancer Research, 2020
Purpose: Insufficient control of infiltrative glioblastoma (GBM) cells is a major cause of treatment failure and tumor recurrence. Hence, detailed insights into pathophysiologic changes that precede GBM recurrence are needed to develop more precise ...
A. Stadlbauer, T. Kinfe, I. Eyüpoglu, Max Zimmermann, Melitta Kitzwoegerer, K. Podar, M. Buchfelder, G. Heinz, S. Oberndorfer, F. Marhold   +9 more
semanticscholar   +1 more source

Low‐Temperature Fabrication of Thymosin β4‐Loaded Soluble Microneedles to Promote Wound Healing by Specific Binding to Downregulated Immune Regulators Vsig4 and IL22rɑ2

Advanced Healthcare Materials, EarlyView.
Schematic diagram depicting the fabrication and application of thymosin β4 (Tβ4)‐loaded microneedle patches for wound treatment. The Tβ4 was loaded into chitosan (CS) and sucrose MNs under mild conditions (4°C, 65% relative humidity). The Tβ4 MN patch specifically binds to the downregulated immune regulators Vsig4 and IL22rα2, thereby accelerating ...
Shilong He, Mei Yuan, Changkang Feng, Yixuan Zhang, Jinjing Che   +4 more
wiley   +1 more source

3D‐Printed Titanium Implants with Bioactive Peptide‐Polysaccharide Scaffolds for Personalized Bone Reconstruction

Advanced Healthcare Materials, EarlyView.
Porous 3D‐printed titanium implants are made bioactive by integration with a supramolecular peptide‐hyaluronic acid nanofibrillar scaffold, without the addition of exogenous cells or growth factors. Uniform filling of the implant architecture promotes vascularized, spatially homogeneous bone regeneration, significantly enhancing osteogenesis throughout
Noam Rattner, Vladimir Perlis, Eran Golden, Ariel Pokhojaev, Rachel Sarig, Itzhak Binderman, Michal Halperin‐Sternfeld, Solomon Dadia, Lihi Adler‐Abramovich   +8 more
wiley   +1 more source

The influence of anisotropic growth and geometry on the stress of solid tumors [PDF]

, 2017
Solid stresses can affect tumor patho-physiology in at least two ways: directly, by compressing cancer and stromal cells, and indirectly, by deforming blood and lymphatic vessels.
Bravo-Castillero, Julián, Conci, Aura, García-Reimbert, Catherine, Guinovart-Díaz, Raúl, Merodio, José, Penta, Raimondo, Ramírez-Torres, Ariel, Rodríguez-Ramos, Reinaldo, Sabina, Federico J., Sevostianov, Igor   +9 more
core   +1 more source