Results 31 to 40 of about 225,607 (242)

The ratio of VEGF/PEDF expression in bone marrow mesenchymal stem cells regulates neovascularization [PDF]

, 2011
Angiogenesis, or neovascularization, is a finely balanced process controlled by pro- and anti-angiogenic factors. Vascular endothelial growth factor (VEGF) is a major pro-angiogenic factor, whereas pigment epithelial-derived factor (PEDF) is the most ...
Crawford, Ross, Fan, Wei, Xiao, Yin
core   +2 more sources

Nanomedicine Approaches for Corneal Diseases

Journal of Functional Biomaterials, 2015
Corneal diseases are the third leading cause of blindness globally. Topical nonsteroidal anti-inflammatory drugs (NSAIDs), steroids, antibiotics and tissue transplantation are currently used to treat corneal pathological conditions.
Shyam S. Chaurasia, Rayne R. Lim, Rajamani Lakshminarayanan, Rajiv R. Mohan   +3 more
doaj   +1 more source

Novel approaches to assessing the signs of atherosclerotic plaque instability in the carotid arteries

Анналы клинической и экспериментальной неврологии, 2017
Introduction. Application of contrast agents in vascular untrasonography has become a new direction in noninvasive assessment of signs of atherosclerotic plaque (ASP) instability; the type of plaque neovascularization being the major sign.
Andrey O. Chechetkin, Lyudmila D. Druina, Anna N. Evdokimenko, Tat'yana S. Gulevskaya, Sergey I. Skrylev, Marine M. Tanashyan   +5 more
doaj   +1 more source

Early markers of angiogenesis and ischemia during bowel conduit neovascularization [PDF]

, 2017
Background Bowel flaps are a good and reliable method to restore the continuity of the aerodigestive tract. Radiated fields, contaminated recipient sites, or depleted recipient vessels may increase the risk for ischemic injury after transfer.
Chen, Hung-chi, Chen, Pei-yu, Ciudad, Pedro, Li, Yun-fen, Lo Torto, Federico, Manrique, Oscar J., Nguyen, Doan-minh, Wong, Alex   +7 more
core   +1 more source

Tumor Neovascularization and Developments in Therapeutics

Cancers, 2019
Tumors undergo fast neovascularization to support the rapid proliferation of cancer cells. Vasculature in tumors, unlike that in wound healing, is immature and affects the tumor microenvironment, resulting in hypoxia, acidosis, glucose starvation, immune
Yuki Katayama, J. Uchino, Y. Chihara, N. Tamiya, Y. Kaneko, Tadaaki Yamada, K. Takayama   +6 more
semanticscholar   +1 more source

EFFICIENCY OF AFLIBERCEPT IN CLINICAL PRACTICE

Офтальмохирургия, 2017
Introduction. Age-related macular degeneration is a leading cause of severe vision loss worldwide, frequently resulting in legal blindness. Implementation of anti-VEGF therapy in clinical practice was an important milestone in the treatment of age ...
A. V. Kulagina
doaj   +1 more source

Effects of BMPER, CXCL10, and HOXA9 on Neovascularization During Early-Growth Stage of Primary High-Grade Glioma and Their Corresponding MRI Biomarkers

Frontiers in Oncology, 2020
Neovascularization is required in high-grade glioma (HGG). The objective of this study was to explore neovascularization-related genes and their corresponding MRI biomarkers during the early-growth stage of HGG.
Wei Xue, Junfeng Zhang, Haipeng Tong, Tian Xie, Xiao Chen, Bo Zhou, Pengfei Wu, Peng Zhong, Xuesong Du, Yu Guo, Youyuan Yang, Heng Liu, Heng Liu, Jingqin Fang, Shunan Wang, Hao Wu, Kai Xu, Weiguo Zhang, Weiguo Zhang   +18 more
doaj   +1 more source

Therapeutic Effect of Human Adipose Tissue-Derived Mesenchymal Stem Cells in Experimental Corneal Failure Due to Limbal Stem Cell Niche Damage [PDF]

, 2017
Producción CientíficaLimbal stem cells are responsible for the continuous renewal of the corneal epithelium. The destruction or dysfunction of these stem cells or their niche induces limbal stem cell deficiency (LSCD) leading to visual loss, chronic pain,
Calonge Cano, Margarita, Galindo de la Rosa, Sara, Herreras Cantalapiedra, José María, López Paniagua, Marina, Mata Sampedro, Ana de la, Nieto Miguel, Teresa, Plata Cordero, María, Rey, Esther   +7 more
core   +2 more sources

Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia [PDF]

, 2006
Background— Stem and progenitor cell therapy is a novel approach to improve neovascularization and function of ischemic tissue. Enhanced tissue expression of chemoattractant factors such as stromal cell–derived factor 1 and vascular endothelial growth ...
Aicher, A, Dimmeler, S, Heeschen, C, Sasaki, K, Urbich, C, Zeiher, AM   +5 more
core   +1 more source

FOXO 1 deletion in chondrocytes rescues diabetes-impaired fracture healing by restoring angiogenesis and reducing apoptosis

Frontiers in Endocrinology, 2023
IntroductionDiabetes mellitus is associated with higher risks of long bone and jaw fractures. It is also associated with a higher incidence of delayed union or non-union.
Mohammed A. Alharbi, Mohammed A. Alharbi, Dana T. Graves   +2 more
doaj   +1 more source