Results 31 to 40 of about 175,739 (194)

Cost effectiveness of treatments for wet age-related macular degeneration [PDF]

open access: yes, 2011
Age-related macular degeneration (AMD) is a leading cause of blindness in people aged >= 50 years. Wet AMD in particular has a major impact on patient quality of life and imposes substantial burdens on healthcare systems.
Annemans, Lieven   +4 more
core   +1 more source

Ranibizumab in patients with dense cataract and proliferative diabetic retinopathy with rubeosis

open access: yesOman Journal of Ophthalmology, 2012
Background: To evaluate the safety of ranibizumab as a surgical adjunct during cataract surgery in patients with proliferative diabetic retinopathy (PDR) with rubeosis, and to evaluate the efficacy and adverse effects of ranibizumab in treating PDR with ...
Yufei Tu   +5 more
doaj   +1 more source

Metabolic Tumor Microenvironment Characterization of Contrast Enhancing Brain Tumors Using Physiologic MRI

open access: yesMetabolites, 2021
The tumor microenvironment is a critical regulator of cancer development and progression as well as treatment response and resistance in brain neoplasms.
Andreas Stadlbauer   +7 more
doaj   +1 more source

Choroidal Neovascularization

open access: yesOphthalmology, 1986
Choroidal neovascularization is now considered to be a most important feature in the pathogenesis and treatment of a number of chorioretinal disorders. Since the recognition of its importance, choroidal neovascularization has been described in clinical and pathologic studies of a variety of different ophthalmologic conditions.
W R, Green, D J, Wilson
openaire   +2 more sources

Soluble Epoxide Hydrolase Inhibition for Ocular Diseases: Vision for the Future [PDF]

open access: yes, 2019
Ocular diseases cause visual impairment and blindness, imposing a devastating impact on quality of life and a substantial societal economic burden. Many such diseases lack universally effective pharmacotherapies.
Corson, Timothy W., Park, Bomina
core   +1 more source

The effects of the subconjunctival injection of bevacizumab (Avastin®) on angiogenesis in the rat cornea

open access: yesAnais da Academia Brasileira de Ciências, 2007
The purpose of this study was to evaluate the effects of the use of the subconjunctival injection of bevacizumab (Avastin®) on angiogenesis in the rat cornea. Corneas of 20 Wistar male rats were cauterized with silver nitrate crystal.
Luiz F.M. Barros, Rubens Belfort-Jr
doaj   +1 more source

Data Augmentation for Improving Proliferative Diabetic Retinopathy Detection in Eye Fundus Images

open access: yesIEEE Access, 2020
Proliferative diabetic retinopathy (PDR) is an advanced diabetic retinopathy stage, characterized by neovascularization, which leads to ocular complications and severe vision loss.
Teresa Araujo   +7 more
doaj   +1 more source

Current concepts on endothelial stem cells definition, location, and markers

open access: yesStem Cells Translational Medicine, 2021
Ischemic vascular disease is a major cause of mortality and morbidity worldwide, and regeneration of blood vessels in perfusion‐deficient tissues is a worthwhile therapeutic goal. The idea of delivering endothelial stem/progenitor cells to repair damaged
Sarah E.J. Chambers   +8 more
doaj   +1 more source

The Durability of Vaccine Efficacy against Ocular HSV-1 Infection Using ICP0 Mutants 0∆NLS and 0∆RING Is Lost over Time

open access: yesPathogens, 2021
Vaccines to viral pathogens in experimental animal models are often deemed successful if immunization enhances resistance of the host to virus challenge as measured by cumulative survival, reduction in virus replication and spread and/or lessen or ...
Daniel J. J. Carr   +2 more
doaj   +1 more source

Investigation of the marine compound spongistatin 1 links the inhibition of PKCα translocation to nonmitotic effects of tubulin antagonism in angiogenesis [PDF]

open access: yes, 2009
The aims of the study were to meet the demand of new tubulin antagonists with fewer side effects by characterizing the antiangiogenic properties of the experimental compound spongistatin 1, and to elucidate nonmitotic mechanisms by which tubulin ...
Bruns, Christiane J.   +7 more
core   +1 more source

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