Results 111 to 120 of about 8,883 (209)

Characterization of the interactions of the nephrin intracellular domain

, 2005
Nephrin is a signalling cell-cell adhesion protein of the Ig superfamily and the first identified component of the slit diaphragm that forms the critical and ultimate part of the glomerular ultrafiltration barrier.
Hellman, Ulf,, Xiao Li Liu, Yi Sun, Jonsson, Anders P., Liu, Xiao Li, Wartiovaara, Jorma, Tryggvason, Karl, Yan, Kunimasa, Pekka Kilpeläinen, Morgunova, Ekaterina, Anders P. Jonsson, Pikkarainen, Timo, Timo Pikkarainen, Karl Tryggvason, Kunimasa Yan, Jorma Wartiovaara, Ekaterina Morgunova, Kilpeläinen, Pekka, Sun, Yi, Ulf Hellman   +19 more
core   +1 more source

Src Kinase Fyn is necessary for nephrin phosphorylation.

, 2016
(A) SYF cells that lack Src, Fyn and Yes were transfected with full-length nephrin. Cells were plated on laminin-coated surface for indicated time points.
Rakesh Verma (151646), Madhusudan Venkatareddy (192316), Puneet Garg (192331), Anne Kalinowski (2138212), Sanjeevkumar R. Patel (238527)   +4 more
core   +1 more source

Dot plots of urine nephrin-to-creatinine ratios.

, 2014
A) Urine nephrin-to-creatinine ratio measurements in 2nd and 3rd trimester recruited patients who developed PE vs. patients who did not develop PE B) Urine nephrin-to-creatinine ratio measurements in 2rd trimester recruited patients who developed PE vs ...
Robert M. Moore (596001), Kwanghee Kim (596000), Hillel W. Cohen (232205), Shuchita Sharma (596002), Andi Qipo (165108), Belinda Jim (322598), Swati Mehta (595999), John C. He (345967)   +7 more
core   +1 more source

Nephrin cellular trafficking and intracellular interactions [Elektronisk resurs]

, 2004
Nephrin is a 180-kDa transmembrane glycoprotein belonging to the immunoglobulin family of cell adhesion molecules. Nephrin has an extracellular part with eight Ig-like motifs, one fibronectin-like domain, a transmembrane region and a short cytoplasmic ...
Liu, XL,
core  

Role of c-Abl and nephrin in podocyte cytoskeletal remodeling induced by angiotensin II

, 2018
Our previous study showed that angiotensin II (Ang II) exposure diminished the interaction between nephrin and c-Abl, then c-Abl mediated SHIP2-Akt pathway in the process of podocyte injury in vivo and vitro. However, the relationship between nephrin and
Yiqiong Ma, Zhentong Zhong, Lu Zhang, Wei Liang, Qian Yang, Yingjie Yang, Guohua Ding   +6 more
core   +1 more source

Reduced nephrin tyrosine phosphorylation impairs podocyte force transmission and accelerates detachment in disease

iScience
Summary: Podocytes are specialized kidney cells that form the slit diaphragm (SD), an intercellular filtration barrier against plasma protein loss. The SD is subject to significant mechanical strain which can be amplified in disease, leading to podocyte ...
Casey R. Williamson, Claire E. Martin, J. Dinesh Kumar, Peihua Lu, Laura A. New, Alice Y. Wang, Nils M. Kronenberg, Malte C. Gather, Paul A. Reynolds, Nina Jones   +9 more
doaj   +1 more source

ISEV2026 Abstract Book

Journal of Extracellular Vesicles, Volume 15, Issue S1, June 2026.
wiley   +1 more source

The importance of detection of autoantibodies to podocytes in primary podocytopathies

Терапевтический архив
Primary podocytopathies, minimal change disease (MCD) and focal segmental glomerulosclerosis (FSGS) are diseases with unknown pathogenesis. Currently, it is assumed that the production of autoantibodies to podocyte antigens is the cause of damage to the ...
Evgenia A. Kharionovskaya, Natalia V. Chebotareva, Evgenia A. Biryukova, Igor I. Alentov, Natalia S. Sergeeva, Sergey V. Moiseev   +5 more
doaj   +1 more source

Nephrin has a half-life of 2.59 weeks at the membrane.

, 2018
(A) Mouse kidney sections stained for nephrin using immunohistochemistry were analyzed for nephrin staining intensity at various time points following tamoxifen-induction using MetaMorph image analysis software.
Rakesh Verma (151646), Ashomathi Mollin (5428904), Theodore Li (5428901), Madhusudan Venkatareddy (192316), Joanna Kukla (5428898), Puneet Garg (192331), Anne Kalinowski (2138212), Gabriel Cara-Fuentes (3949763), Sanjeevkumar R. Patel (238527)   +8 more
core   +1 more source

zApoL1 KD rescue in zebrafish larvae by human Nephrin mRNA.

, 2016
The rescue of the nephrin KD by human Nephrin mRNA (hmRNA) resulted in zebrafish larvae (CADE) without edema and with an intact filtration barrier (A).
Uwe Zimmermann (214606), Ahmed M. Kotb (2637514), Frank Dombrowski (2637508), Karlhans Endlich (112716), Antje Blumenthal (112861), Silke Vogelgesang (2637511), Ole Simon (2637517), Nicole Endlich (170572), Kerstin Amann (186160)   +8 more
core   +1 more source