Results 121 to 130 of about 12,068 (208)
Proteinuric Kidney Diseases: A Podocyte's Slit Diaphragm and Cytoskeleton Approach
Frontiers in Medicine, 2018 Proteinuric kidney diseases are a group of disorders with diverse pathological mechanisms associated with significant losses of protein in the urine.
Samuel Mon-Wei Yu +4 more
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Urinary podocyte markers in diabetic kidney disease [PDF]
Kidney Research and Clinical PracticePodocytes are involved in maintaining kidney function and are a major focus of research on diabetic kidney disease (DKD). Urinary biomarkers derived from podocyte fragments and molecules have been proposed for the diagnosis and monitoring of DKD. Various
Chuanlei Li, Cheuk-Chun Szeto
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SAT-439 PODOCIN REGULATES THE NEPHRIN-NEPHRIN DISTANCE IN THE GLOMERULAR PORE [PDF]
Kidney International Reports, 2020 M. KÉTSZERI +7 more
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The importance of detection of autoantibodies to podocytes in primary podocytopathies
Терапевтический архивPrimary podocytopathies, minimal change disease (MCD) and focal segmental glomerulosclerosis (FSGS) are diseases with unknown pathogenesis. Currently, it is assumed that the production of autoantibodies to podocyte antigens is the cause of damage to the ...
Evgenia A. Kharionovskaya +5 more
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Evaluation of methodologies in anti-nephrin autoantibody detection
Kidney InternationalABSTRACTRecent studies discovered the prominent presence of anti-nephrin autoantibodies in minimal change disease, steroid-sensitive nephrotic syndrome and/or post-transplant recurrent focal segmental glomerulosclerosis (FSGS). However, widely different, and often unconventional autoantibody detection methods were used among these studies, making it ...
Pan Liu +11 more
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Biologia e genetica del podocita [PDF]
, 2015 Progresses in podocyte biology have been strictly connected with genetic advances; the identification of genes mutated in familial and sporadic forms of nephrotic syndrome has been followed by functional studies of the encoded proteins, revealing ...
Armelloni, Silvia +9 more
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Autophagy in patients with lupus nephritis and its effect on podocyte related protein expression
Linchuang shenzangbing zazhi, 2020 Objective To investigate the autophagy in patients with lupus nephritis(LN)and its effect on podocyte related protein expression.Methods A total of 69 LN patients(LN group),including 50 cases of systemic lupus erythematosus(SLE group)and 50 patients with
LI Zhang-hong, ZHANG Rui-rui, LUO Qiu-ju
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Expression Of Nephrin In Early Diagnosis Of Diabetic Nephropathy
Pakistan Journal of Medicine and DentistryBackground & Objectives: Diabetic nephropathy occurs as a result of proximal tubule dysfunction with podocyte damage due to increased advanced glycation end-products’ insult in diabetes.
Moazzam A. Shahid +3 more
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Longitudinal Study of the Vascular Glycocalyx and Urinary Podocyte Markers During Pregnancy
Journal of the American Heart Association: Cardiovascular and Cerebrovascular DiseaseBackground We aimed to assess the longitudinal changes of glycocalyx, a proteoglycan/glycoprotein layer that lines and protects endothelial cells in normotensive pregnancies (NPs); to correlate glycocalyx parameters with kidney injury markers (podocin ...
Oscar Garcia Valencia +13 more
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骨形态发生蛋白-7通过TGFβ/smad信号通路抑制高糖诱导下足细胞的转分化
Zhongguo shiyan zhenduanxue, 2014 目的通过观察骨形态发生蛋白-7（BMP-7）对高糖环境培养下足细胞p-smad2/3、nephrin、desmin表达的影响探讨BMP-7抑制足细胞转分化机制。方法以体外培养的小鼠永生化足细胞为研究对象,将其分为以下4组:正常糖组（NG组,含D-葡萄糖5.5mmol/L）、高糖刺激组（HG组,含D-葡萄糖30mmol/L）、高糖+BMP-7干预组（BMP-7组,含D-葡萄糖30mmol/L+400ng/ml rhBMP-7）、甘露醇对照组（MN组,含D-葡萄糖5.5mmol/L+甘露醇24.5mmol ...
徐建伟, 刘丽秋, 赵小丽
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