Results 121 to 130 of about 12,065 (211)

Stem cells and fluid flow drive cyst formation in an invertebrate excretory organ.

, 2015
Cystic kidney diseases (CKDs) affect millions of people worldwide. The defining pathological features are fluid-filled cysts developing from nephric tubules due to defective flow sensing, cell proliferation and differentiation.
Alexander, R., Alvarado, A., Lakshmanaperumal, N., McClain, M., McKinney, S., Rink, J., Vu, H.   +6 more
core   +1 more source

SAT-439 PODOCIN REGULATES THE NEPHRIN-NEPHRIN DISTANCE IN THE GLOMERULAR PORE [PDF]

Kidney International Reports, 2020
M. KÉTSZERI, V. Antal, G. Schay, A. Ungvári-Veres, K. Csókay, M. Kellermayer, D. Karancsiné Menyhárd, K. Tory   +7 more
openaire   +1 more source

Evaluation of methodologies in anti-nephrin autoantibody detection

Kidney International
ABSTRACTRecent studies discovered the prominent presence of anti-nephrin autoantibodies in minimal change disease, steroid-sensitive nephrotic syndrome and/or post-transplant recurrent focal segmental glomerulosclerosis (FSGS). However, widely different, and often unconventional autoantibody detection methods were used among these studies, making it ...
Pan Liu, Shuping Liu, Vidhi Dalal, Jerome Lane, Paolo Cravedi, Kirk Campbell, Andrea Angeletti, Xinfang Xie, Elisa Gessaroli, Eleonora Forte, Lorenzo Gallon, Jing Jin   +11 more
openaire   +4 more sources

The importance of detection of autoantibodies to podocytes in primary podocytopathies

Терапевтический архив
Primary podocytopathies, minimal change disease (MCD) and focal segmental glomerulosclerosis (FSGS) are diseases with unknown pathogenesis. Currently, it is assumed that the production of autoantibodies to podocyte antigens is the cause of damage to the ...
Evgenia A. Kharionovskaya, Natalia V. Chebotareva, Evgenia A. Biryukova, Igor I. Alentov, Natalia S. Sergeeva, Sergey V. Moiseev   +5 more
doaj   +1 more source

Autophagy in patients with lupus nephritis and its effect on podocyte related protein expression

Linchuang shenzangbing zazhi, 2020
Objective To investigate the autophagy in patients with lupus nephritis(LN)and its effect on podocyte related protein expression.Methods A total of 69 LN patients(LN group),including 50 cases of systemic lupus erythematosus(SLE group)and 50 patients with
LI Zhang-hong, ZHANG Rui-rui, LUO Qiu-ju
doaj  

Expression Of Nephrin In Early Diagnosis Of Diabetic Nephropathy

Pakistan Journal of Medicine and Dentistry
Background & Objectives: Diabetic nephropathy occurs as a result of proximal tubule dysfunction with podocyte damage due to increased advanced glycation end-products’ insult in diabetes.
Moazzam A. Shahid, Saeeda Baig, Adnan M. Zubairi, Farha Ahmed   +3 more
doaj  

Biologia e genetica del podocita [PDF]

, 2015
Progresses in podocyte biology have been strictly connected with genetic advances; the identification of genes mutated in familial and sporadic forms of nephrotic syndrome has been followed by functional studies of the encoded proteins, revealing ...
Armelloni, Silvia, Corbelli, Alessandro, Giardino, Laura, Ikehata, Masami, Li, Min, Mattinzoli, Deborah, Pignatari, Chiara, Rastaldi, Maria Pia, Watanabe, Shojiro, Zennaro, Cristina   +9 more
core  

Longitudinal Study of the Vascular Glycocalyx and Urinary Podocyte Markers During Pregnancy

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background We aimed to assess the longitudinal changes of glycocalyx, a proteoglycan/glycoprotein layer that lines and protects endothelial cells in normotensive pregnancies (NPs); to correlate glycocalyx parameters with kidney injury markers (podocin ...
Oscar Garcia Valencia, Sonja Suvakov, Haitao Tu, Darah Dilmaghani, Natasa M. Milic, Tracey L. Weissgerber, Vladimir Dokic, Paul Gavrilovici, Jennet Hatamova, Jing Miao, Wendy M. White, Muthuvel Jayachandran, Karl Nath, Vesna D. Garovic   +13 more
doaj   +1 more source

厄贝沙坦对早期糖尿病肾脏疾病大鼠足细胞nephrin和podocin表达的影响

Linchuang shenzangbing zazhi, 2014
目的 观察厄贝沙坦（irbesartan）对糖尿病肾脏疾病（diabetic kidney disease,DKD）大鼠足细胞裂孔隔膜蛋白分子（nephrin和podocin）表达的影响,探讨厄贝沙坦对DKD的防治作用。方法 以高脂高糖喂养8周联合小剂量链脲佐菌素（30 rmg/kg）建立DKD大鼠模型,将DKD大鼠模型随机分为2组:厄贝沙坦组及模型对照组;另设正常对照组。厄贝沙坦组给予厄旦沙坦(50 mg·kg-1·d-1),另外2组每日给予等量0.9%生理盐水灌胃。各组于治疗前及药物干预后第4、8 ...
岳少姮
doaj  

Nephrotic syndrome caused by recurrent podocytopathy after living donor renal transplantation with elevated anti-nephrin antibody levels: a case report and a review

Renal Replacement Therapy
Background Approximately 95% of patients with idiopathic nephrotic syndrome (INS) have a favorable prognosis, though 4–5% progress to end-stage renal disease. The recurrence rate of INS following kidney transplantation is approximately 30%.
Ryoichi Miyazaki, Kyoko Miyagi, Tatsuhito Miyanaga, Yoko Shirai, Kenichiro Miura, Motoshi Hattori, Satoshi Hara, Kiyoaki Ito, Ichiro Mizushima, Yasunori Iwata   +9 more
doaj   +1 more source