Results 41 to 50 of about 1,206 (172)

Modeling Monogenic Human Nephrotic Syndrome in the Drosophila Garland Cell Nephrocyte. [PDF]

Journal of the American Society of Nephrology, 2017
Steroid-resistant nephrotic syndrome is characterized by podocyte dysfunction. Drosophila garland cell nephrocytes are podocyte-like cells and thus provide a potential in vivo model in which to study the pathogenesis of nephrotic syndrome. However, relevant pathomechanisms of nephrotic syndrome have not been studied in nephrocytes.
Tobias Hermle, D. Braun, M. Helmstädter, T. Huber, F. Hildebrandt   +4 more
semanticscholar   +4 more sources

Dysfunction of Mitochondrial Dynamics in Drosophila Model of Diabetic Nephropathy

Life, 2021
Although mitochondrial dysfunction is associated with the development and progression of diabetic nephropathy (DN), its mechanisms are poorly understood, and it remains debatable whether mitochondrial morphological change is a cause of DN. In this study,
Kiyoung Kim, Sun Joo Cha, Hyun-Jun Choi, Jeong Suk Kang, Eun Young Lee   +4 more
doaj   +1 more source

Peptide‐Enabled Thrombus‐Targeting Nanoparticles for Highly Effective Targeted CT Imaging and Eradication of Thrombi

Advanced Functional Materials, Volume 33, Issue 41, October 9, 2023., 2023
A thrombus‐targeting peptide derived from phage display is conjugated onto silica‐coated bismuth‐cored nanoparticles, which are then loaded with a chemotherapeutic drug. Under the guidance of the peptide, they can selectively target and bind to the thrombus. They effectively combat the thrombus by photothermal and chemo‐therapy.
Leihao Lu, Qing Bao, Yao Miao, Qichao Cheng, Yuyin Chen, Shuxu Yang, Chuanbin Mao, Mingying Yang   +7 more
wiley   +1 more source

MiniCORVET is a Vps8-containing hemocyte- and nephrocyte-specific early endosomal tether in Drosophila [PDF]

, 2016
Yeast studies identified two heterohexameric tethering complexes, which consist of 4 shared (Vps11, Vps16, Vps18 and Vps33) and 2 specific subunits: Vps3 and Vps8 (CORVET) versus Vps39 and Vps41 (HOPS).
Akbar, Baker, Balderhaar, Balderhaar, Bechtel, Belyaeva, Bröcker, Csordás, Gillingham, Guan, Hong, Jiang, Kim, Klinger, Koenig, Kosaka, Kurucz, Kurucz, Kümmel, Lachmann, Li, Lindmo, Lloyd, Lu, Markgraf, Morrison, Munier, Márkus, Ostrowicz, Patterson, Peplowska, Perini, Peterson, Plemel, Port, Pulipparacharuvil, Richardson, Rieder, Rusten, Schuldiner, Seals, Sevrioukov, Shestopal, Solinger, Srivastava, Südhof, Takáts, Takáts, Tanaka, van der Kant, Warner, Wartosch, Weavers, Wickner, Wucherpfennig, Wurmser, Zhang, Zhuang, Zick   +58 more
core   +6 more sources

Tailup expression in Drosophila larval and adult cardiac valve cells

genesis, Volume 61, Issue 1-2, March 2023., 2023
Summary In Drosophila larvae, the direction of blood flow within the heart tube, as well as the diastolic filling of the posterior heart chamber, is regulated by a single cardiac valve. This valve is sufficient to close the heart tube at the junction of the ventricle and the aorta and is formed by only two cells; both are integral parts of the heart ...
Christian Meyer, Laetitia Bataillé, Maik Drechsler, Achim Paululat   +3 more
wiley   +1 more source

The Impact of Virtual Reality Technology on Jordan’s Learning Environment and Medical Informatics among Physicians

International Journal of Computer Games Technology, Volume 2023, Issue 1, 2023., 2023
The purpose of this study is to look into the components that affect the behavioral intention of Jordanians to use Virtual Reality Technology in the Learning Environment (VRTLE). For the educational and entertainment industries, virtual reality presents both obstacles and opportunities.
Malik Jawarneh, Marwan Alshar′e, Deshinta Arrova Dewi, Mohammad Al Nasar, Rasha Almajed, Amer Ibrahim, Fabrizio Balducci   +6 more
wiley   +1 more source

Characterization and mode of action analysis of black soldier fly (Hermetia illucens) larva‐derived hemocytes

Insect Science, Volume 29, Issue 4, Page 1071-1095, August 2022., 2022
Graphical Abstract: The first detailed description of circulating hemocyte types of Black Soldier Fly (Hermetia illucens) by morphological, cytometrical, and functional characteristics reveals three distinct hemocyte types. The most abundant cell type (∼98%) are the plasmatocytes, which appear to be highly variable in their shape and size and are the ...
Yvette M. von Bredow, Ariane Müller, Philipp F. Popp, Denis Iliasov, Christoph‐Rüdiger von Bredow   +4 more
wiley   +1 more source

Saxagliptin protects against diabetic nephropathy by inhibiting caspase 3/PARP-1-dependent nephrocyte apoptosis

Experimental and Therapeutic Medicine, 2021
Saxagliptin (SAX) can protect against tissue damage caused by diabetic nephropathy. However, whether this compound can restore kidney function, and its specific mechanism of action remain unclear.
X. Xing, Shuang Guo, Yusheng Liu, Jiangying Kuang, Zhiwei Huang, Xin Wang, Qinghua Lu   +6 more
semanticscholar   +1 more source

Histopathological and Biochemical Comparative Study of Copper Oxide Nanoparticles and Copper Sulphate Toxicity in Male Albino Mice Reproductive System

International Journal of Biomaterials, Volume 2022, Issue 1, 2022., 2022
Copper (Cu) is an essential trace element for the efficient functioning of living organisms. Cu can enter the body in different ways, and when it surpasses the range of biological tolerance, it can have negative consequences. The use of different nanoparticles, especially metal oxide nanoparticles, is increasingly being expanded in the fields of ...
Manal M. S. AL-Musawi, Hanady Al-Shmgani, Genan A. Al-Bairuty, Sameh Ali   +3 more
wiley   +1 more source

Nephrocytes are part of the spectrum of filtration epithelial diversity [PDF]

Cell and Tissue Research, 2020
AbstractThe excretory system produces urine by ultrafiltration via a filtration epithelium. Podocytes are widely found as filtration epithelial cells in eucoelomates. In some animal taxa, including insects and crustaceans, nephrocytes serve to separate toxic substances from the body fluid, in addition to podocytes.
Takayuki Miyaki, Yuto Kawasaki, Akira Matsumoto, Soichiro Kakuta, Tatsuo Sakai, Koichiro Ichimura   +5 more
openaire   +2 more sources