Results 51 to 60 of about 541 (160)
Ecotoxicology and Environmental Safety, 2023 High alkalinity stress was considered as a major risk factor for aquatic animals surviving in saline-alkaline water. However, few information exists on the effects of alkalinity stress in crustacean species.
Qianqian Ge +3 more
doaj +1 more source
Cubilin and Amnionless Mediate Protein Reabsorption in Drosophila Nephrocytes [PDF]
Journal of the American Society of Nephrology, 2013 The insect nephrocyte and the mammalian glomerular podocyte are similar with regard to filtration, but it remains unclear whether there is an organ or cell type in flies that reabsorbs proteins. Here, we show that the Drosophila nephrocyte has molecular, structural, and functional similarities to the renal proximal tubule cell.
Fujian, Zhang +4 more
openaire +2 more sources
Phospholipid scramblase 1: an essential component of the nephrocyte slit diaphragm. [PDF]
Cell Mol Life SciAbstractBlood ultrafiltration in nephrons critically depends on specialized intercellular junctions between podocytes, named slit diaphragms (SDs). Here, by studying a homologous structure found in Drosophila nephrocytes, we identify the phospholipid scramblase Scramb1 as an essential component of the SD, uncovering a novel link between membrane ...
Castillo-Mancho V +4 more
europepmc +4 more sources
Functional and ultrastructural studies of apical-basal polarity in Drosophila nephrocytes [PDF]
, 2018 Intact apical-basal cell polarity is one of the mandatory requirements of proper cell and tissue development. Especially for more complex cell types, accurate cell function depends significantly on correct establishment of cell polarity.
Mendl, Gudrun
core +1 more source
Adult pericardial nephrocyte function is dependent on dKlf15. [PDF]
, 2015 (A & B) dKlf15 was conditionally silenced in adult nephrocytes using Hand-Target (Target) to drive UAS-dKlf15RNAi. Flies were reared at 18°C until eclosion then either maintained at 18°C (A’, B’; no knock-down) or placed at 29°C (A”, B”; RNAi permitted ...
Paul S. Hartley (244067) +6 more
core +1 more source
Using Drosophila Nephrocytes to Understand the Formation and Maintenance of the Podocyte Slit Diaphragm. [PDF]
Front Cell Dev Biol, 2022 The podocyte slit diaphragm (SD) is an essential component of the glomerular filtration barrier and its disruption is a common cause of proteinuria and many types of kidney disease. Therefore, better understanding of the pathways and proteins that play key roles in SD formation and maintenance has been of great interest.
van de Leemput J, Wen P, Han Z.
europepmc +5 more sources
Comprehensive functional analysis of Rab GTPases in Drosophila nephrocytes [PDF]
Cell and Tissue Research, 2017 The Drosophila nephrocyte is a critical component of the fly renal system and bears structural and functional homology to podocytes and proximal tubule cells of the mammalian kidney. Investigations of nephrocyte cell biological processes are fundamental to understanding the insect renal system.
Yulong, Fu +5 more
openaire +2 more sources
Networks that link cytoskeletal regulators and diaphragm proteins underpin filtration function in Drosophila nephrocytes [PDF]
, 2018 Insect nephrocytes provide a valuable model for kidney disease, as they are structurally and functionally homologous to mammalian kidney podocytes. They possess an exceptional macromolecular assembly, the nephrocyte diaphragm (ND), which serves as a ...
Skaer, Helen +7 more
core +1 more source
Fly: a model to study the podocyte [PDF]
, 2014 Diseases of the renal system are typically difficult to treat due to the inherent complexity of the organ. A key cell type is the podocyte, which is gaining interest as a key regulator of filtration and potentially central to various kidney dysfunctions.
Cagan, R.L., Na, J.
core +1 more source
Біологія тварин, 2023 Principles of reptile treatment are significantly different from the drug therapy for mammals and birds, which is primarily due to anatomical and physiological peculiarities of reptiles.
R. S. Dankovych, V. I. Chuliuk
doaj +1 more source