Results 71 to 80 of about 541 (160)
Mediators of Inflammation, Volume 2026, Issue 1, 2026.Ischemia‐reperfusion injury (IRI) presents an intractable challenge for kidney donors, especially in the era of donation after circulatory death (DCD). Based on in‐depth studies of the renal IRI phenomenon, and the mechanisms involved, an increasing number of soluble mediators are being frequently associated with cellular dysfunction, cell death, and ...
Ji Zhang +10 more
wiley +1 more source
Disease Models & Mechanisms, 2020 Aldosterone is produced by the mammalian adrenal cortex to modulate blood pressure and fluid balance; however, excessive, prolonged aldosterone promotes fibrosis and kidney failure.
Wenjing Zheng, Karen Ocorr, Marc Tatar
doaj +1 more source
Reviews in Aquaculture, Volume 17, Issue 4, September 2025.Single‐cell sequencing sheds light on cellular diversity, development, and immune evolution in fish and invertebrates, offering new insights into environmental adaptation and evolutionary biology. ABSTRACT Single‐cell sequencing (SCS) technology has revolutionized the study of cellular heterogeneity by enabling the exploration of biological processes ...
Chongbin Hu +5 more
wiley +1 more source
Acta Physiologica, Volume 241, Issue 8, August 2025.ABSTRACT Aim Podocytes, highly specialized epithelial cells located in the glomerulus of the kidney, are essential to the filtration barrier that ensures separation of blood and urine. These cells exhibit a unique architecture, characterized by an intricate network of foot processes interconnected by slit diaphragms, which serve as a critical selective
Desiree Loreth +2 more
wiley +1 more source
A Drug Screening Platform for Podocytopathies in Drosophila Nephrocytes
Journal of the American Society of NephrologyKey Points We developed a fast assay testing Drosophila nephrocyte function, suitable for whole-animal drug screening in these podocyte-like cells.
Dominik Spitz +5 more
openaire +2 more sources
Nanotoxicological evaluation of oxidative responses in rat nephrocytes induced by cadmium
International Journal of Nanomedicine, 2013 The aim of this study was to investigate the interaction of cadmium chloride with mineral elements in rat nephrocytes in terms of the biosynthesis of nanocomplexes. The results show that selenium supplementation enhanced cadmium accumulation in kidneys.
Trabelsi,Hamdi +5 more
openaire +5 more sources
Evolved and Plastic Gene Expression in Adaptation of a Specialist Fly to a Novel Niche
Molecular Ecology, Volume 34, Issue 4, February 2025.ABSTRACT How gene expression evolves to enable divergent ecological adaptation and how changes in gene expression relate to genomic architecture are pressing questions for understanding the mechanisms enabling adaptation and ecological speciation. Furthermore, how plasticity in gene expression can both contribute to and be affected by the process of ...
Rachel A. Steward +6 more
wiley +1 more source
, 2009 Recent insights have defined the central role of podocytes both in rare genetic diseases and as a general determinant of the progression of human glomerular diseases. In a recent issue of Nature, Weavers et al.
Simons, Matias, Huber, Tobias B.
core +1 more source
Tau reduction impairs nephrocyte function in Drosophila
BMB ReportsTau, a microtubule-associated protein, is known for its significant involvement in neurodegenerative diseases. While various molecular and immunohistochemical techniques have confirmed the presence of Tau in podocytes, its precise function within these cells remains elusive.
Lee, Jiyoung +6 more
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Origin and evolution of microvilli
Biology of the Cell, Volume 116, Issue 11, November 2024.Microvilli are widespread organelles of animal cells that frequently play a role in sensation and feeding. Ansel et al. reconstitute their origin and evolution by performing a broad morphological survey of microvilli in animals and their unicellular relatives, coupled with a bioinformatic study of the phylogenetic distribution of the main microvillar ...
Mylan Ansel +3 more
wiley +1 more source