Results 141 to 150 of about 3,007 (176)

Interplay between microtubule interactome, myonuclei mechanotransduction, and positioning in myopathies. [PDF]

Nucleus
Castellano L, Caillol D, Streichenberger N, Gache V.   +3 more
europepmc   +1 more source

Attenuated Nuclear Tension Regulates Progerin-Induced Mechanosensitive Nuclear Wrinkling and Chromatin Remodeling. [PDF]

Adv Sci (Weinh)
Park JE, Jo J, Xu K, Lee SA, Han SB, Lee Y, Cho WK, Li B, Kim SH, Kim DH.   +9 more
europepmc   +1 more source

Current biomarker development in myotonic dystrophies. [PDF]

J Neurol
Larsen M, Mendelsohn DH, Kleefeld F, Meinke P, Schoser B.   +4 more
europepmc   +1 more source

Nesprin interchain associations control nuclear size [PDF]

Cellular and Molecular Life Sciences, 2012
Nesprins-1/-2/-3/-4 are nuclear envelope proteins, which connect nuclei to the cytoskeleton. The largest nesprin-1/-2 isoforms (termed giant) tether F-actin through their N-terminal actin binding domain (ABD).
Angelika A. Noegel, Martin W Goldberg, Iakowos Karakesisoglou   +2 more
exaly   +4 more sources

Nesprin-2 epsilon: A novel nesprin isoform expressed in human ovary and Ntera-2 cells

Biochemical and Biophysical Research Communications, 2011
The nuclear envelope-associated cytoskeletal protein, nesprin-2, is encoded by a large gene containing several internal promoters that produce shorter isoforms. In a study of Ntera-2 teratocarcinoma cells, a novel isoform, nesprin-2-epsilon, was found to
Roland G. Roberts, Glenn E Morris, Le Thanh Lam   +2 more
exaly   +5 more sources

Nesprin-1 mutations in human and murine cardiomyopathy [PDF]

Journal of Molecular and Cellular Cardiology, 2010
Mutations in LMNA, the gene encoding the nuclear membrane proteins, lamins A and C, produce cardiac and muscle disease. In the heart, these autosomal dominant LMNA mutations lead to cardiomyopathy frequently associated with cardiac conduction system disease. Herein, we describe a patient with the R374H missense variant in nesprin-1alpha, a protein that
Megan J. Puckelwartz
exaly   +3 more sources

Some of the next articles are maybe not open access.

Related searches:

Nesprin-1 impact on tumorigenic cell phenotypes

Molecular Biology Reports, 2019
The largest protein of the nuclear envelope (NE) is Nesprin-1 which forms a network along the NE interacting with actin, Emerin, Lamin, and SUN proteins. Mutations in the SYNE1 gene and reduction in Nesprin-1 protein levels have been reported to correlate with several age related diseases and cancer.
İlknur Sur-Erdem, Angelika A. Noegel
exaly   +3 more sources

Nesprin-1 role in DNA damage response

Nucleus, 2014
Nuclear envelope (NE) proteins have fundamental roles in maintaining nuclear structure, cell signaling, chromatin organization, and gene regulation, and mutations in genes encoding NE components were identified as primary cause of a number of age associated diseases and cancer.
Angelika A. Noegel, Sascha Neumann
exaly   +3 more sources