Results 141 to 150 of about 982,945 (306)

Rest‐activity patterns across development in two mouse models of autism and epilepsy

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Sleep disturbances are common in individuals with autism spectrum disorder (ASD) and epilepsy and are increasingly recognized as comorbidities that affect disease severity and quality of life. This study investigated rest‐activity patterns across development in two genetic mouse models relevant to ASD and epilepsy: synapsin 2 (Syn2 ...
Ipsa Dash   +4 more
wiley   +1 more source

Disturbance from restoration reseeding is associated with short‐term topsoil carbon loss and alters soil bacterial communities and functions in degraded alpine meadows of the Qinghai–Xizang Plateau

open access: yesGrassland Research, EarlyView.
Restoration reseeding of degraded alpine meadows increased aboveground vegetation but was associated with short‐term topsoil carbon loss, coinciding with a microbial strategy shift from resident carbon‐preserving to carbon‐spending bacterial guilds. Abstract Background Restoration of degraded ecosystems is widely promoted as a nature‐based solution ...
Long‐Tao Zhu   +9 more
wiley   +1 more source

Testing Multiple Non-nested Factor Demand Systems, [PDF]

open access: yes
Empirical factor demand analysis typically involves making a choice from among several competing non-nested functional forms. Each of the commonly used factor demand systems, such as Translog, Generalized Leontief, Quadratic, and Generalized McFadden ...
Michael McAleer, Matteo Manera
core  

Establishment of Salivary Gland Tumors Arising in Salivary Gland‐Specific EWSR1::ATF1 Transgenic Mice

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Salivary gland carcinomas are uncommon malignancies with various histological subtypes harboring fusion genes. The EWSR1::ATF1 fusion gene, resulting from a translocation between chromosomes 12 and 22, is frequently observed in hyalinizing clear cell carcinoma (HCCC). However, the role of this fusion gene in HCCC oncogenesis remains
Yuri Hirai   +13 more
wiley   +1 more source

Improving genetic diagnosis of hereditary tumor syndromes: From expanded gene panels to functional genomics

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Genetic tumor risk syndromes (genturis) contribute substantially to the overall cancer burden and provide opportunities for early detection, prevention, and individualized treatment. Yet, many affected individuals remain undiagnosed due to restrictive testing criteria and challenges in variant interpretation.
Mayra Sauer   +11 more
wiley   +1 more source

UTILIZAÇÃO DA PCR NESTED PARA DETECÇÃO DE Toxoplasma gondii NO SANGUE DE OVELHAS EXPERIMENTALMENTE INFECTADAS

open access: yesBrazilian Journal of Veterinary Medicine, 2013
Objetivou-se com esse estudo avaliar a sensibilidade da PCR e PCR nested na detecção de T. gondiino sangue de ovelhas experimentalmente infectadas com taquizoítos via sêmen. Foram colhidas amostras de sangue de 30 ovelhas infectadas com diferentes doses:
Érica Paes Barreto Xavier de Moraes   +4 more
doaj  

The Association Between Human Papillomavirus and Prostate Cancer: A Systematic Review and Meta‐Analysis

open access: yesInternational Journal of Cancer, EarlyView.
ABSTRACT Human papillomavirus (HPV), the necessary cause of cervical cancer, is associated with an increased risk of other anogenital cancers. While HPV has frequently been detected in prostate specimens, its role in prostate carcinogenesis remains controversial. We synthesized and meta‐analyzed the epidemiological literature on the association between
Sarah Botting‐Provost   +5 more
wiley   +1 more source

Association of carcinoma of the gallbladder with typhoid carriage in a typhoid endemic area using nested PCR

open access: yes, 2008
Background: Although well studied the association between chronic typhoid carrier state and carcinoma of the gallbladder (CaGB) remains unproven.Methodology: The study was performed at a tertiary care medical center in North India and involved 52 ...
Gopal Nath1, Yogesh Kumar Singh1, Kailash Kumar2, Anil Kumar Gulati1, Vijay Kumar Shukla3, Ajay Kumar Khanna3, Sunil Kumar Tripathi4, Ashok Kumar Jain5, Mohan Kumar6, Tej Bali Singh7
core  

Sel1l preserves condylar cartilage matrix homeostasis by regulating PERK signaling

open access: yesInterdisciplinary Medicine, EarlyView.
Our study revealed that the expression of Sel1l was downregulated in OA cartilage and that Sel1l deficiency induced cartilage catabolism. Mechanistically, Sel1l depletion aberrantly activated PERK signaling and resulted in ER stress. PERK inhibition rescued the phenotype of Sel1l‐deficient chondrocytes and alleviated TMJOA pathogenesis.
Xinqi Huang   +3 more
wiley   +1 more source

Detecção de rotavírus em amostras de águas de superfície através de técnicas moleculares e de cultivo celular [PDF]

open access: yes, 2008
TCC(graduação) - Universidade Federal de Santa Catarina. Centro de Ciências Biológicas. Biologia.Atualmente a contaminação do ambiente aquático e conseqüentemente dos recursos hídricos, vêm tomando importância frente à preocupação com a escassez da água.
Moresco, Vanessa
core  

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