Results 61 to 70 of about 982,945 (306)
Advanced Science, EarlyView.A novel epitranscriptomic mechanism in rheumatoid arthritis is uncovered: NSUN2 promotes disease via m5C‐dependent stabilization of ICMT mRNA, fueling the migration and invasion of pathogenic RA FLS. Targeting this axis with engineered nanoparticles (Ce/SAA NPs) effectively inhibits disease progression, presenting a precise therapeutic strategy ...
Ruiru Li +15 more
wiley +1 more source
Evaluation of Group specific Nested PCR for detection of Bluetongue virus [PDF]
Veterinary World, 2009 During the present study RT-PCR and nested PCR was evaluated for the detection of BTV in blood samples collected from suspected cases of bluetongue. Due to conserved nature, NS1 gene was targeted for the development of partial length and nested PCR assay.
Chauhan H C +4 more
doaj
Revista da Sociedade Brasileira de Medicina Tropical, 2008 Diagnosis of human herpesvirus-7 active infection in transplant patients has proved difficult, because this virus is ubiquitous and can cause persistent infections in the host.
Ronaldo Luis Thomasini +7 more
doaj +1 more source
Development of a duplex PCR assay for detection of Brachyspira hyodysenteriae and Brachyspira pilosicoli in pig feces [PDF]
, 2003 A duplex PCR (D-PCR) amplifying portions of the Brachyspira hyodysenteriae NADH oxidase gene and the B. pilosicoli 16S rRNA gene was developed and then tested on DNA extracted from 178 porcine fecal samples. The feces also underwent anaerobic culture and
Phillips, N.D., La, T., Hampson, D.J.
core
Advanced Science, EarlyView.Herein we report a boron‐based pyrazole, (Borsantrazole ‐ a small molecule that selectively targets oxidative stress) that significantly increases survival, reduces weight loss, delays disease onset, and affects global protein changes in the SOD1‐G37R mouse model of ALS.
Nitesh Sanghai +9 more
wiley +1 more source
Advanced Science, EarlyView.Engineered exosomal siRNA delivery platform enables systemic, neuron‐targeted RNA transport across the blood–brain barrier. Surface functionalization with rabies virus glycoprotein‐derived peptide facilitates receptor‐mediated transcytosis, achieving efficient cytosolic delivery and robust gene silencing. Targeting RIPK3 suppresses necroptosis, reduces
Chi Zhang +9 more
wiley +1 more source
Detection of Mycobacterium bovis in bovine and bubaline tissues using nested-PCR for TbD1. [PDF]
PLoS ONE, 2014 In the present study, a nested-PCR system, targeting the TbD1 region, involving the performance of conventional PCR followed by real-time PCR, was developed to detect Mycobacterium bovis in bovine/bubaline tissue homogenates.
Cristina P Araújo +14 more
doaj +1 more source
Detection of Candida albicans by Nested PCR
Journal of the Japanese Association for Infectious Diseases, 1994 A nested PCR assay was developed for the diagnosis of Candida albicans infection. A segment of the C. albicans beta-tubulin gene was amplified in this assay that was sensitive with the detection limit of 10 fg DNA of C. albicans. This assay was found to be specific by obtaining the negative results with 13 organisms (5 other Candida, 2 Cryptococcus, 3 ...
openaire +3 more sources
A nested real-time PCR assay has an increased sensitivity\ud suitable for detection of viruses in aerosol studies [PDF]
, 2009 Aims: Influenza is commonly spread by infectious aerosols; however, detection\ud of viruses in aerosols is not sensitive enough to confirm the characteristics of\ud virus aerosols.
P. Perrott +9 more
core +1 more source
Primers used for nested PCR and sequencing.
, 2022 Primers used for nested PCR and sequencing.
David Tarragó (4048396) +2 more
core +1 more source