Results 61 to 70 of about 49,281,268 (309)

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Mapping of Real-time Applications on Network-on-Chip based MPSOCS. [PDF]

, 2011
Mapping of real time applications on real time NoC based MPSoCs. With the recent developments in semiconductor technology it becomes possible to integrate many different processing elements on single chip, this solution is known as a System-on-Chip ...
Mesidis, Paris-alexandros
core  

Energy-aware Application Mapping onto 3D Mesh-Based Network-on-Chip using Heuristic Mapping Algorithms [PDF]

Journal of Universal Computer Science
Network-on-chip (NoC) architectures have emerged as a potential solution for facilitating communication between processing elements (PEs) in modern multi-core systems.
Kiran K A, Jaison Jacob
doaj   +3 more sources

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Quest for the ultimate network-on-chip

, 2012
The NaNoC project is progressing toward an innovative design platform for multicore systems based on future networks-on-chip. This platform enables the design, manufacturing and management of networks-on-chip by tackling new requirements of future ...
J. Flich, F. O. Sem Jacobsen, A. Strano, V. Todorov, L. Di Gregorio, STRANO, Alessandro, D. Bertozzi, F. Angiolini, T. Bjerregaard, F. O. Sem-Jacobsen, BERTOZZI, Davide, F. Silla   +11 more
core   +1 more source

Low-cost on-chip clock jitter measurement scheme [PDF]

, 2014
In this paper, we present a low-cost, on-chip clock jitter digital measurement scheme for high performance microprocessors. It enables in situ jitter measurement during the test or debug phase.
Giaffreda, Daniele, Rahman A., Omana, Martin, Rossi D., Tam, S., Omana M., Omana, M., Metra C., Metra, C., Mak, TM, Rahman, A., Rossi, Daniele, S. Tam, Giaffreda, D., Metra, Cecilia, Raman, Asifur, A. Rahman, Mak, T.M., Mak T. M., D. Giaffreda, TM Mak, Giaffreda D., Tam, Simon, Tam S., OMANA, MARTIN EUGENIO, Rossi, D.   +25 more
core   +1 more source

Hardware-Software Complex for Network-on-Chip Prototyping Using Multiple FPGAs

IEEE Access
This paper presents a hardware-software multi-FPGA complex designed for hardware prototyping of networks-on-chip (NoCs). The rationale for the use of multiple FPGAs for NoC prototyping is given.
Mikhail Y. Romashikhin, Aleksandr Y. Romanov   +1 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Reliability Analysis of On-Chip Communication Architectures: An MPEG-2 Video Decoder Case Study

, 2011
In this paper, we present reliability analysis and comparison between on-chip communication architectures: dominant shared-bus AMBA and emerging network-on-chip (NoC); in the presence of single-event upsets (SEUs) using MPEG-2 video decoder as a case ...
Rishad A. Shafik, Bashir M. Al-Hashimi, Al-Hashimi, Bashir, Shafik, Rishad   +3 more
core   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source