Results 61 to 70 of about 132,420 (284)
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Network on Chip for FPGA: Development of a test system for Network on Chip [PDF]
, 2011 Testing and verification of digital systems is an essential part of product develop-ment. The Network on Chip(NoC), as a new paradigm within interconnections;has a specific need for testing. This is to determine how performance and prop-erties of the NoC
Namork, Magnus Krokum
core
Network on Chip: a New Approach of QoS Metric Modeling Based on Calculus Theory
, 2011 A NoC is composed by IP cores (Intellectual Propriety) and switches connected among themselves by communication channels. End-to-End Delay (EED) communication is accomplished by the exchange of data among IP cores.
Nasri, Salem
core +1 more source
Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
A Manycore Vision Processor for Real-Time Smart Cameras
Sensors, 2021 Real-time image processing and computer vision systems are now in the mainstream of technologies enabling applications for cyber-physical systems, Internet of Things, augmented reality, and Industry 4.0.
Bruno A. da Silva +4 more
doaj +1 more source
Estimation of Optimized Energy and Latency Constraints for Task Allocation in 3d Network on Chip
, 2014 In Network on Chip (NoC) rooted system, energy consumption is affected by task scheduling and allocation schemes which affect the performance of the system.
Jha, Mohit, Jha, Vaibhav, Sharma, GK
core +1 more source
FEBS Open Bio, EarlyView.Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source