Results 41 to 50 of about 124,516 (258)
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Network-on-chip: the intelligence is in the wire [PDF]
IEEE International Conference on Computer Design: VLSI in Computers and Processors, 2004. ICCD 2004. Proceedings., 2004 In this paper, we describe how network-on-chip (NoC) can be the next major challenge to implement complex and function-rich applications in advanced manufacturing processes at 90 nm technology and below. Although much progress has been made in connecting the various components encompassed in communication networks for system-on-chip (SoC) designs (e.g.,
Gérard Mas, Philippe Martin 0005
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FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Energy-aware Application Mapping onto 3D Mesh-Based Network-on-Chip using Heuristic Mapping Algorithms [PDF]
Journal of Universal Computer ScienceNetwork-on-chip (NoC) architectures have emerged as a potential solution for facilitating communication between processing elements (PEs) in modern multi-core systems.
Kiran K A, Jaison Jacob
doaj +3 more sources
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
On the Design of a Photonic Network-on-Chip [PDF]
First International Symposium on Networks-on-Chip (NOCS'07), 2007 Recent remarkable advances in nanoscale silicon-photonic integrated circuitry specifically compatible with CMOS fabrication have generated new opportunities for leveraging the unique capabilities of optical technologies in the on-chip communications infrastructure.
Assaf Shacham +2 more
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Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
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Hardware-Software Complex for Network-on-Chip Prototyping Using Multiple FPGAs
IEEE AccessThis paper presents a hardware-software multi-FPGA complex designed for hardware prototyping of networks-on-chip (NoCs). The rationale for the use of multiple FPGAs for NoC prototyping is given.
Mikhail Y. Romashikhin +1 more
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Design Technologies for Networks on Chips
First International Symposium on Networks-on-Chip (NOCS'07), 2007 Summary form only given. Networks on chips provide structured solutions for fast and low-power interconnect, but need to be adapted to the performance and physical design requirements of the host chip. Efficient and optimal design of such networks is an error-prone, tedious and time-consuming task.
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Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
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