Results 121 to 130 of about 4,454 (194)

Proinflammatory Mechanism of N-Glycolylneuraminic Acid in Mice through Regulating the Gut Microbiota [PDF]

open access: yesShipin Kexue
In this study, the effect of 18 weeks of dietary supplementation of porcine submaxillary gland mucin (PSM) as an abundant source of N-hydroxyacetylneuraminic acid (Neu5Gc) on the expression of proteins involved in the nuclear factor kappa-B (NF-κB ...
HE Leli, LIU Chuxin, XIAO Yi, SHEN Qingwu, WU Yanyang
doaj   +1 more source

The Poor Performance of Neu5Gc for Endometrial Receptivity in Embryo Transfer

open access: yesJournal of Bio-X Research
Neu5Gc is a common sialic acid in mammals, but humans cannot synthesize it independently. When Neu5Gc in the diet enters the body, the body produces antibodies against Neu5Gc, which in turn promotes the immune response and chronic inflammation and may be
Yunfeng Lin, Qicai Liu
doaj   +1 more source

A systematic review reveals conflicting evidence for the prevalence of antibodies against the sialic acid ‘xenoautoantigen’ Neu5Gc in humans and the need for a standardised approach to quantification

open access: yesFrontiers in Molecular Biosciences
Despite an array of hypothesised implications for health, disease, and therapeutic development, antibodies against the non-human sialic acid N-glycolylneuraminic acid (Neu5Gc) remain a subject of much debate.
Esme Hutton   +5 more
doaj   +1 more source

Anti-Neu5Gc Antibody Kit Protocol - ELISA v1

open access: yes, 2016
This protocol is essentially the same as a standard ELISA protocol, with one major exception – all animal compounds must be avoided in buffers, etc. because they contain Neu5Gc, which will interfere with antibody activity and result in misleading data.
openaire   +1 more source

MRI study of the effect of Sialic acid supplementation on piglets working memory [PDF]

open access: yes, 2015
唾液酸(Sialicacid,Sia)是自然界中一系列酰基化形式神经氨酸衍生物的统称。唾液酸具有多种生物学功能,如:促进细胞的增殖、分化和参与识别;与病原微生物相互作用,参与机体免疫反应;促进神经系统发育,易化记忆形成,提高学习能力;且在大脑发育的关键时期,进行干预可以对大脑造成远期的不可逆的影响。许多动物实验表明唾液酸对大脑发育、学习和记忆能力产生重要影响,仔猪因大脑发育阶段和解剖结构与新生婴儿相似,适合用做研究婴儿脑区变化的动物模型。磁共振成像技术因其对软组织空间分辨率高 ...
吕春龙
core  

Koyunlarda, CMAH geninin Neu5Gc sialik asidiyle ilişkisinin araştırılması

open access: yes, 2022
Meat is a food source rich in nutrients that are essential for healthy human growth and development. Despite the fact that meat eating is now linked to disease including cancer, cardiovascular disease and diabetes, meat has played a crucial role in human evolution.
openaire   +1 more source

Anti-Neu5Gc Antibody Kit Protocol - Flow Cytometry v1

open access: yes, 2016
Anti-Neu5Gc may be used for staining cells prior to analysis by Flow Cytometry. This kit contains all the essential components needed to identify Neu5Gc on the surface of cells by flow cytometry. Use of the blocking agent (Neu5Gc Assay Blocking Solution) provided in the kit is essential, as commonly used blocking agents invariably contain serum, or ...
openaire   +1 more source

Assessment of Sialic Acid Content in Dairy Products from Buffalo’s and Goat’s Milk Compared to Cow’s Milk

open access: yesDairy
Sialic acids (SIAs) are bioactive compounds present in glycoproteins and glycolipids, playing key roles in human physiology. N-acetylneuraminic acid (Neu5Ac), the only sialic acid synthesized by humans, contributes to neurodevelopment and immune function,
Simona Rinaldi   +5 more
doaj   +1 more source

El mono humanizado : la búsqueda genética de lo que nos hace humanos [PDF]

open access: yes, 2005
Desde su empleo como justificación para mantener un racismo de especie, el concepto de humano ha evolucionado a un punto de tal inclusividad que la distinción entre hombre y chimpancé se vuelve borrosa.
Concepción de la Rúa   +2 more
core  

Anti-Neu5Gc Antibody Kit Protocol - Flow Cytometry v2

open access: yes, 2017
Anti-Neu5Gc may be used for staining cells prior to analysis by Flow Cytometry. This kit contains all the essential components needed to identify Neu5Gc on the surface of cells by flow cytometry. Use of the blocking agent (Neu5Gc Assay Blocking Solution) provided in the kit is essential, as commonly used blocking agents invariably contain serum, or ...
openaire   +1 more source

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