Results 31 to 40 of about 1,925,336 (327)
Zebrafish arl6ip1 is required for neural crest development during embryogenesis.
PLoS ONE, 2012 BackgroundAlthough the embryonic expression pattern of ADP ribosylation factor-like 6 interacting protein 1 (Arl6ip1) has been reported, its function in neural crest development is unclear.Methods/principal findingsWe found that knockdown of Arl6ip1 ...
Chi-Tang Tu +3 more
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Single-Cell Multiomic Approaches Reveal Diverse Labeling of the Nervous System by Common Cre-Drivers
Frontiers in Cellular Neuroscience, 2021 Neural crest development involves a series of dynamic, carefully coordinated events that result in human disease when not properly orchestrated. Cranial neural crest cells acquire unique multipotent developmental potential upon specification to generate ...
Rachel A. Keuls +7 more
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Cell, 2010 The neural crest is a transient population of cells that emerges from the neural tube during the early stages of embryonic development. Neural crest cells are unique to vertebrates and have properties similar to stem cells, including the ability to differentiate into many cell types (i.e., multipotency) and to regenerate.
Sauka-Spengler, T, Bronner, M
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Neuroblastoma—A Neural Crest Derived Embryonal Malignancy
Frontiers in Molecular Neuroscience, 2019 Neuroblastoma is a neural crest derived malignancy of the peripheral nervous system and is the most common and deadliest tumor of infancy. It is characterized by clinical heterogeneity with a disease spectrum ranging from spontaneous regression without ...
J. Johnsen +2 more
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The neural crest and neural crest defects
Biomedical Reviews, 2002 The neural crest is a fascinating embryonic tissue for more than one reason. In the adult organism it gives rise to an array of distinct cell types and tissues. It is responsible for many birth defects, familial diseases and malignancies, and it is amenable to the elucidation of mechanisms that regulate stem cell differentiation.
Maya Sieber-Blum, Zhijian Zhang
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Genetics Underlying the Interactions between Neural Crest Cells and Eye Development
Journal of Developmental Biology, 2020 The neural crest is a unique, transient stem cell population that is critical for craniofacial and ocular development. Understanding the genetics underlying the steps of neural crest development is essential for gaining insight into the pathogenesis of ...
Jochen Weigele, Brenda L. Bohnsack
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The diverse neural crest: from embryology to human pathology
Development, 2019 We review here some of the historical highlights in exploratory studies of the vertebrate embryonic structure known as the neural crest. The study of the molecular properties of the cells that it produces, their migratory capacities and plasticity, and ...
H. Etchevers, E. Dupin, N. L. Le Douarin
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Natural Sciences, 2022 The origin of the neurons and glia in the olfactory system of vertebrates has been controversial, with different cell types attributed to being of ectodermal placode versus neural crest lineage, depending upon the species.
Alison Koontz +2 more
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Neural crest-derived mesenchymal cells require Wnt signaling for their development and drive invagination of the telencephalic midline. [PDF]
PLoS ONE, 2014 Embryonic neural crest cells contribute to the development of the craniofacial mesenchyme, forebrain meninges and perivascular cells. In this study, we investigated the function of ß-catenin signaling in neural crest cells abutting the dorsal forebrain ...
Youngshik Choe +2 more
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Cardiovascular Development and the Colonizing Cardiac Neural Crest Lineage
The Scientific World Journal, 2007 Although it is well established that transgenic manipulation of mammalian neural crest-related gene expression and microsurgical removal of premigratory chicken and Xenopus embryonic cardiac neural crest progenitors results in a wide spectrum of both ...
Paige Snider +3 more
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