Results 11 to 20 of about 211,749 (307)
Frontiers in Immunology, 2023 Sialic acids are terminal sugars of the cellular glycocalyx and are highly abundant in the nervous tissue. Sialylation is sensed by the innate immune system and acts as an inhibitory immune checkpoint.
Tawfik Abou Assale +5 more
doaj +1 more source
Clinical and Applied Thrombosis/Hemostasis, 2021 Background: To investigate the factors associated with elevated fibrinogen (Fbg) levels in COVID-19 patients with and without diabetes (DM) and impaired fasting glucose (IFG).
Zhenzhou Wang MD +5 more
doaj +1 more source
MicroRNA-142a-3p regulates neurogenic skeletal muscle atrophy by targeting Mef2a
Molecular Therapy: Nucleic Acids, 2023 Peripheral nerve injury can lead to progressive muscle atrophy and poor motor function recovery, which is a difficult point of treatment, and the mechanism needs to be further explored.
Xinyi Gu +7 more
doaj +1 more source
The glia response after peripheral nerve injury: A comparison between Schwann cells and olfactory ensheathing cells and their uses for neural regenerative therapies [PDF]
, 2017 The peripheral nervous system (PNS) exhibits a much larger capacity for regeneration than the central nervous system (CNS). One reason for this difference is the difference in glial cell types between the two systems.
Barton, Matthew J. +4 more
core +2 more sources
Polycistronic Delivery of IL-10 and NT-3 Promotes Oligodendrocyte Myelination and Functional Recovery in a Mouse Spinal Cord Injury Model. [PDF]
, 2020 One million estimated cases of spinal cord injury (SCI) have been reported in the United States and repairing an injury has constituted a difficult clinical challenge.
Anderson, Aileen J +8 more
core +1 more source
Scientific Reports, 2022 Sialic acids as the terminal caps of the cellular glycocalyx play an essential role in self-recognition and were shown to modulate complement processes via interaction between α2,3-linked sialic acids and complement factor H. Previously, it was suggested
Anahita Shahraz +9 more
doaj +1 more source
Spinal Progenitor-Laden Bridges Support Earlier Axon Regeneration Following Spinal Cord Injury. [PDF]
, 2018 Impact statementSpinal cord injury (SCI) results in loss of tissue innervation below the injury. Spinal progenitors have a greater ability to repair the damage and can be injected into the injury, but their regenerative potential is hampered by their ...
Anderson, Aileen J +5 more
core +1 more source
Depressive patient‐derived GABA interneurons reveal abnormal neural activity associated with HTR2C
EMBO Molecular Medicine, 2022 Major depressive disorder with suicide behavior (sMDD) is a severe mood disorder, bringing tremendous burden to family and society. Although reduced gamma amino butyric acid (GABA) level has been observed in postmortem tissues of sMDD patients, the ...
Kaiqin Lu +11 more
doaj +1 more source
The effects of age and ganglioside composition on the rate of motor nerve terminal regeneration following antibody-mediated injury in mice [PDF]
, 2013 Gangliosides are glycosphingolipids highly enriched in neural plasma membranes, where they mediate a diverse range of functions and can act as targets for auto-antibodies present in human immune-mediated neuropathy sera.
Cunningham, Madeleine E. +4 more
core +1 more source
Cell Reports, 2019 Summary: Under food deprivation conditions, Drosophila larvae exhibit increases in locomotor speed and synaptic bouton numbers at neuromuscular junctions (NMJs).
Keisuke Kamimura +4 more
doaj +1 more source