Results 11 to 20 of about 213,330 (331)

The various routes to functional regeneration in the central nervous system [PDF]

open access: yes, 2020
© The Author(s), 2020. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Echeverri, K.
Echeverri, Karen
core   +1 more source

Polycistronic Delivery of IL-10 and NT-3 Promotes Oligodendrocyte Myelination and Functional Recovery in a Mouse Spinal Cord Injury Model. [PDF]

open access: yes, 2020
One million estimated cases of spinal cord injury (SCI) have been reported in the United States and repairing an injury has constituted a difficult clinical challenge.
Anderson, Aileen J   +8 more
core   +1 more source

Hyaluronan, neural stem cells and tissue reconstruction after acute ischemic stroke. [PDF]

open access: yes, 2013
Focal stroke is a disabling disease with lifelong sensory, motor and cognitive impairments. Given the paucity of effective clinical treatments, basic scientists are developing novel options for protection of the affected brain and regeneration of lost ...
Carmichael, S Thomas, Moshayedi, Pouria
core   +1 more source

NLRP3 deficiency decreases alcohol intake controlling anxiety-like behavior via modification of glutamatergic transmission in corticostriatal circuits

open access: yesJournal of Neuroinflammation, 2022
Background Alcohol use disorders result from repeated binge and chronic alcohol consumption followed by negative effects, such as anxiety, upon cessation. This process is associated with the activation of NLRP3 inflammasome-mediated responses.
Ziyi Li   +9 more
doaj   +1 more source

6’-sialyllactose ameliorates the ototoxic effects of the aminoglycoside antibiotic neomycin in susceptible mice

open access: yesFrontiers in Immunology, 2023
Sialic acids are terminal sugars of the cellular glycocalyx and are highly abundant in the nervous tissue. Sialylation is sensed by the innate immune system and acts as an inhibitory immune checkpoint.
Tawfik Abou Assale   +5 more
doaj   +1 more source

Potential use of human periapical cyst-mesenchymal stem cells (hPCy-MSCs) as a novel stem cell source for regenerative medicine applications [PDF]

open access: yes, 2017
Mesenchymal stem cells (MSCs) are attracting growing interest by the scientific community due to their huge regenerative potential. Thus, the plasticity of MSCs strongly suggests the utilization of these cells for regenerative medicine applications.
Codispoti, Bruna   +6 more
core   +2 more sources

Determinants of Increased Fibrinogen in COVID-19 Patients With and Without Diabetes and Impaired Fasting Glucose

open access: yesClinical and Applied Thrombosis/Hemostasis, 2021
Background: To investigate the factors associated with elevated fibrinogen (Fbg) levels in COVID-19 patients with and without diabetes (DM) and impaired fasting glucose (IFG).
Zhenzhou Wang MD   +5 more
doaj   +1 more source

MicroRNA-142a-3p regulates neurogenic skeletal muscle atrophy by targeting Mef2a

open access: yesMolecular Therapy: Nucleic Acids, 2023
Peripheral nerve injury can lead to progressive muscle atrophy and poor motor function recovery, which is a difficult point of treatment, and the mechanism needs to be further explored.
Xinyi Gu   +7 more
doaj   +1 more source

Depressive patient‐derived GABA interneurons reveal abnormal neural activity associated with HTR2C

open access: yesEMBO Molecular Medicine, 2022
Major depressive disorder with suicide behavior (sMDD) is a severe mood disorder, bringing tremendous burden to family and society. Although reduced gamma amino butyric acid (GABA) level has been observed in postmortem tissues of sMDD patients, the ...
Kaiqin Lu   +11 more
doaj   +1 more source

Characterizing the Retinal Phenotype of the Thy1-h[A30P]α-syn Mouse Model of Parkinson’s Disease

open access: yesFrontiers in Neuroscience, 2021
Despite decades of research, disease-modifying treatments of Parkinson’s disease (PD), the second most common neurodegenerative disease worldwide, remain out of reach.
Lien Veys   +11 more
doaj   +1 more source

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