Results 1 to 10 of about 7,508 (163)
Synthesis of N-Glycolylneuraminic Acid (Neu5Gc) and Its Glycosides [PDF]
Sialic acids constitute a family of negatively charged structurally diverse monosaccharides that are commonly presented on the termini of glycans in higher animals and some microorganisms.
Anoopjit Singh Kooner, Hai Yu, Xi Chen
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Production of
Background Two sequential enzymes in the production of sialic acids, N-acetyl-D-glucosamine 2-epimerase (GlcNAc 2-epimerase) and N-acetyl-D-neuraminic acid aldolase (Neu5Ac aldolase), were overexpressed as double-tagged gene fusions.
Cheng Chung-Hsien +5 more
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Multiple extracellular polymeric substance pathways transcribed by Accumulibacter and the flanking community during aerobic granule formation and after influent modification [PDF]
Aerobic granular sludge is a biological wastewater treatment process in which a microbial community forms a granular biofilm. The role of Candidatus Accumulibacter in the production of a biofilm matrix composed of extracellular polymeric substances was ...
Laëtitia Cardona +4 more
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Many locks to one key: N-acetylneuraminic acid binding to proteins [PDF]
Sialic acids play crucial roles in cell surface glycans of both eukaryotic and prokaryotic organisms, mediating various biological processes, including cell–cell interactions, development, immune response, oncogenesis and host–pathogen interactions. This
KanagaVijayan Dhanabalan +3 more
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The structural characterization of lipopolysaccharides has critical implications for some biomedical applications, and marine bacteria are an inimitable source of new glyco-structures potentially usable in medicinal chemistry.
Maxim S. Kokoulin +2 more
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Sialic acids, sialoconjugates and enzymes of their metabolism in fungi
Sialic acids (Sia) represent a set of derivatives of nine-carbon sugar neuraminic acid that occupy a terminal position in oligosaccharide chains located on the surface of cells. They are very important for several physiological and pathological processes,
Rumyana Eneva +4 more
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Anti–SARS-CoV-2 Natural Products as Potentially Therapeutic Agents
Severe acute respiratory syndrome–related coronavirus-2 (SARS-CoV-2), a β-coronavirus, is the cause of the recently emerged pandemic and worldwide outbreak of respiratory disease.
Cheorl-Ho Kim
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Carbon utilization phenome of Leptospira interrogans serovar Manilae strain K64
Background: Leptospirosis, an acute febrile disease caused by the pathogenic species of genus Leptospira, is one of the neglected emerging zoonoses that is of global public health concern.
Ailyn G Manglicmot-Yabes +2 more
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We tested the hypothesis that (1) mucus production can be included in the cell response to iron deficiency; (2) mucus binds iron and increases cell metal uptake; and subsequently (3) mucus impacts the inflammatory response to particle exposure.
Andrew J. Ghio +3 more
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Background: Sialic acids are widely distributed in nature and have biological relevance owing to their varied structural and functional roles. Immobilized neuraminidase can selectively remove terminal N-acetyl neuraminic acid from glycoproteins without ...
Lucía Bidondo +4 more
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