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Synthesis of N-Glycolylneuraminic Acid (Neu5Gc) and Its Glycosides [PDF]

open access: yesFrontiers in Immunology, 2019
Sialic acids constitute a family of negatively charged structurally diverse monosaccharides that are commonly presented on the termini of glycans in higher animals and some microorganisms.
Anoopjit Singh Kooner, Hai Yu, Xi Chen
doaj   +4 more sources

Multiple extracellular polymeric substance pathways transcribed by Accumulibacter and the flanking community during aerobic granule formation and after influent modification [PDF]

open access: yesApplied and Environmental Microbiology
Aerobic granular sludge is a biological wastewater treatment process in which a microbial community forms a granular biofilm. The role of Candidatus Accumulibacter in the production of a biofilm matrix composed of extracellular polymeric substances was ...
Laëtitia Cardona   +4 more
doaj   +2 more sources

Glycolyl-neuraminic Acid in Ox Brain Gangliosides [PDF]

open access: bronzeNature, 1965
IN this communication we report the presence of glycolyl-neuraminic acid in sialic acids from ox brain gangliosides. Our method of analysis consisted of the following six steps: (i) gangliosides were extracted from ox brain grey matter and purified according to a method which we have previously described1; (ii) gangliosides so obtained were hydrolysed ...
Guido Tettamanti   +3 more
openalex   +3 more sources

Many locks to one key: N-acetylneuraminic acid binding to proteins [PDF]

open access: yesIUCrJ
Sialic acids play crucial roles in cell surface glycans of both eukaryotic and prokaryotic organisms, mediating various biological processes, including cell–cell interactions, development, immune response, oncogenesis and host–pathogen interactions. This
KanagaVijayan Dhanabalan   +3 more
doaj   +2 more sources

Structure of the Lipooligosaccharide from the Deep-Sea Marine Bacterium Idiomarina zobellii KMM 231T, Isolated at a Depth of 4000 Meters

open access: yesMarine Drugs, 2022
The structural characterization of lipopolysaccharides has critical implications for some biomedical applications, and marine bacteria are an inimitable source of new glyco-structures potentially usable in medicinal chemistry.
Maxim S. Kokoulin   +2 more
doaj   +1 more source

Sialic acids, sialoconjugates and enzymes of their metabolism in fungi

open access: yesBiotechnology & Biotechnological Equipment, 2021
Sialic acids (Sia) represent a set of derivatives of nine-carbon sugar neuraminic acid that occupy a terminal position in oligosaccharide chains located on the surface of cells. They are very important for several physiological and pathological processes,
Rumyana Eneva   +4 more
doaj   +1 more source

Anti–SARS-CoV-2 Natural Products as Potentially Therapeutic Agents

open access: yesFrontiers in Pharmacology, 2021
Severe acute respiratory syndrome–related coronavirus-2 (SARS-CoV-2), a β-coronavirus, is the cause of the recently emerged pandemic and worldwide outbreak of respiratory disease.
Cheorl-Ho Kim
doaj   +1 more source

Carbon utilization phenome of Leptospira interrogans serovar Manilae strain K64

open access: yesLife Sciences, Medicine and Biomedicine, 2021
Background: Leptospirosis, an acute febrile disease caused by the pathogenic species of genus Leptospira, is one of the neglected emerging zoonoses that is of global public health concern.
Ailyn G Manglicmot-Yabes   +2 more
doaj   +1 more source

Mucus increases cell iron uptake to impact the release of pro-inflammatory mediators after particle exposure

open access: yesScientific Reports, 2023
We tested the hypothesis that (1) mucus production can be included in the cell response to iron deficiency; (2) mucus binds iron and increases cell metal uptake; and subsequently (3) mucus impacts the inflammatory response to particle exposure.
Andrew J. Ghio   +3 more
doaj   +1 more source

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