Results 21 to 30 of about 4,989,359 (237)

A Method for the Determination of Neuraminidase Activity in the Presence of Added Neuraminic Acids or Potential Inhibitors. [PDF]

open access: bronzeActa Chemica Scandinavica, 1969
Leif Holmquist   +7 more
openalex   +2 more sources

Enzymatic synthesis and properties of glycoconjugates with legionaminic acid as a replacement for neuraminic acid [PDF]

open access: yesGlycobiology, 2010
In addition to sialic acid, bacteria produce several other nonulosonic acids, including legionaminic acid (Leg). This has exactly the same stereochemistry as sialic acid, with the added features of 9-deoxy and 7-amino groups. In order to explore the biological effects of replacing sialic acid residues (Neu5Ac) in glycoconjugates with Leg in its ...
Watson, David C.   +3 more
openaire   +4 more sources

Structure of the Lipooligosaccharide from the Deep-Sea Marine Bacterium Idiomarina zobellii KMM 231T, Isolated at a Depth of 4000 Meters

open access: yesMarine Drugs, 2022
The structural characterization of lipopolysaccharides has critical implications for some biomedical applications, and marine bacteria are an inimitable source of new glyco-structures potentially usable in medicinal chemistry.
Maxim S. Kokoulin   +2 more
doaj   +1 more source

Anti–SARS-CoV-2 Natural Products as Potentially Therapeutic Agents

open access: yesFrontiers in Pharmacology, 2021
Severe acute respiratory syndrome–related coronavirus-2 (SARS-CoV-2), a β-coronavirus, is the cause of the recently emerged pandemic and worldwide outbreak of respiratory disease.
Cheorl-Ho Kim
doaj   +1 more source

Carbon utilization phenome of Leptospira interrogans serovar Manilae strain K64

open access: yesLife Sciences, Medicine and Biomedicine, 2021
Background: Leptospirosis, an acute febrile disease caused by the pathogenic species of genus Leptospira, is one of the neglected emerging zoonoses that is of global public health concern.
Ailyn G Manglicmot-Yabes   +2 more
doaj   +1 more source

Mucus increases cell iron uptake to impact the release of pro-inflammatory mediators after particle exposure

open access: yesScientific Reports, 2023
We tested the hypothesis that (1) mucus production can be included in the cell response to iron deficiency; (2) mucus binds iron and increases cell metal uptake; and subsequently (3) mucus impacts the inflammatory response to particle exposure.
Andrew J. Ghio   +3 more
doaj   +1 more source

Functional and structural analyses reveal that a dual domain sialidase protects bacteria from complement killing through desialylation of complement factors.

open access: yesPLoS Pathogens, 2023
The complement system is the first line of innate immune defense against microbial infections. To survive in humans and cause infections, bacterial pathogens have developed sophisticated mechanisms to subvert the complement-mediated bactericidal activity.
Nicholas D Clark   +8 more
doaj   +1 more source

Cold-Active Shewanella glacialimarina TZS-4T nov. Features a Temperature-Dependent Fatty Acid Profile and Putative Sialic Acid Metabolism

open access: yesFrontiers in Microbiology, 2021
Species of genus Shewanella are among the most frequently identified psychrotrophic bacteria. Here, we have studied the cellular properties, growth dynamics, and stress conditions of cold-active Shewanella strain #4, which was previously isolated from ...
Muhammad Suleman Qasim   +10 more
doaj   +1 more source

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