Results 51 to 60 of about 9,739 (239)

Mismatch negativity, social cognition, and functional outcomes in patients after traumatic brain injury

Neural Regeneration Research, 2015
Mismatch negativity is generated automatically, and is an early monitoring indicator of neuronal integrity impairment and functional abnormality in patients with brain injury, leading to decline of cognitive function.
Hui-yan Sun, Qiang Li, Xi-ping Chen, Lu-yang Tao   +3 more
doaj   +1 more source

Decrease of IL-1β and TNF in the Spinal Cord Mediates Analgesia Produced by Ankle Joint Mobilization in Complete Freund Adjuvant-Induced Inflammation Mice Model

Frontiers in Physiology, 2022
ObjectiveThis study aims to investigate the effects of ankle joint mobilization (AJM) on mechanical hyperalgesia and peripheral and central inflammatory biomarkers after intraplantar (i.pl.) Complete Freund’s Adjuvant (CFA)-induced inflammation ...
Carlos Minoru Omura, Daniela Dero Lüdtke, Daniela Dero Lüdtke, Verônica Vargas Horewicz, Paula Franson Fernandes, Taynah de Oliveira Galassi, Afonso Shiguemi Inoue Salgado, Juliete Palandi, Juliete Palandi, Heloiza dos Santos Baldança, Heloiza dos Santos Baldança, Edsel B. Bittencourt, Josiel Mileno Mack, Josiel Mileno Mack, Josiel Mileno Mack, Lynsey A. Seim, Daniel Fernandes Martins, Franciane Bobinski   +17 more
doaj   +1 more source

Safety and effectiveness of propranolol in severely burned patients: systematic review and meta-analysis [PDF]

, 2017
Background The objective of this systematic review was to determine the effectiveness and safety of propranolol compared to placebo or usual care for improving clinical relevant outcomes in severely burned patients (TBSA \u3e20%).
Ferrada, Paula, Foianini, Jorge Esteban, García-Perdomo, Herney Andrés, Gomez, Diego Andrés, Manzano-Nunez, Ramiro, Ordoñez Delgado, Carlos Alberto   +5 more
core   +3 more sources

Effects of Oral Administration of the Probiotic Lactobacillus rhamnosus GG on the Proteomic Profiles of Cerebrospinal Fluid and Immunoregulatory Signaling in the Hippocampus of Adult Male Rats

Neuroimmunomodulation
Introduction: The microbiome-gut-brain axis, by modulating bidirectional immune, metabolic, and neural signaling pathways in the host, has emerged as a target for the prevention and treatment of psychiatric and neurological disorders.
Kelsey M. Loupy, Lamya'a M. Dawud, Cristian A. Zambrano, Thomas Lee, Jared D. Heinze, Ahmed I. Elsayed, James E. Hassell Jr., Heather M. D'Angelo, Matthew G. Frank, Steven F. Maier, Lisa A. Brenner, Christopher A. Lowry   +11 more
doaj   +1 more source

Butyrylcholinesterase and Acetylcholinesterase polymorphisms in Multiple Sclerosis patients: Implication in peripheral inflammation [PDF]

, 2018
Multiple Sclerosis (MS) is an autoimmune disease, having not fully understood aetiology, and both genetic and environmental factors contribute to the pathogenesis of the disease.
Costantini, Erica, D'Angelo, Chiara, D'Aurora, Marco, Di Bari, Maria, Di Nicola, Marta, Franchi, Sara, Galizia, Sabrina, Gasperini, Claudio, Gatta, Valentina, Orlando, Viviana, Reale, Marcella, Ruggieri, Serena, Stuppia, Liborio, Tata, Ada Maria   +13 more
core   +3 more sources

Neuro‐Immune Crosstalk: Molecular Mechanisms, Biological Functions, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 2, February 2026.
Neurons, immune cells, and other cellular components within the disease microenvironment (such as stromal cells and tumor cells) constitute a dynamically evolving ecosystem. Neurons directly modulate immune cell activity and inflammatory responses through the release of neurotransmitters (e.g., norepinephrine and CGRP), while also promoting tumor ...
Xin Guo, Hui Liu, Yu‐Jing Song, Jian‐Hua Wang, Danfeng Liu, Zhi‐Wei Zheng, Jia‐Jun Li, Boya Li, An Song, Wei He, Lei‐Lei Yang, Shuo Wang   +11 more
wiley   +1 more source

Astrocytic responses to binge ethanol in male and female mice: An examination of astrocytic glutamate transporters and density changes in the dorsal hippocampus

Alcohol, Clinical and Experimental Research, Volume 50, Issue 1, January 2026.
The current work tested the hypothesis that sex differences in alcohol's effects are mediated by astrocytes. Using immunohistochemistry, qRT‐PCR, and ELISAs, we found that nondependent, binge‐like alcohol‐induced increases in hippocampal astrocyte density were more robust in females.
Candace Swepson, DaQuan R. Mebane, Diego Correia, Esohe H. Imafidon, Christopher P. Trevisani, James Nelson, S. Alex Marshall   +6 more
wiley   +1 more source

The Endogenous Opioid System in Schizophrenia and Treatment Resistant Schizophrenia: Increased Plasma Endomorphin 2, and κ and μ Opioid Receptors Are Associated with Interleukin-6

Diagnostics, 2020
Background: activation of the immune-inflammatory response system (IRS) and the compensatory immune-regulatory system (CIRS) plays a key role in schizophrenia (SCZ) and treatment resistant SCZ.
Shatha Rouf Moustafa, Khalid F. Al-Rawi, Drozdstoi Stoyanov, Arafat Hussein Al-Dujaili, Thitiporn Supasitthumrong, Hussein Kadhem Al-Hakeim, Michael Maes   +6 more
doaj   +1 more source

Acetylcholine-treated murine dendritic cells promote inflammatory lung injury [PDF]

, 2019
In recent years a non-neuronal cholinergic system has been described in immune cells, which is often usually activated during the course of inflammatory processes. To date, it is known that Acetylcholine (ACh), a neurotransmitter extensively expressed in
Alcain, Julieta María, Candolfi, Marianela, Geffner, Jorge Raúl, Gori, María Soledad, Jancic, Carolina Cristina, Moreno Ayala, Mariela Alejandra, Salamone, Gabriela Veronica, Vanzulli, Silvia, Vermeulen, Elba Monica   +8 more
core   +1 more source

Treponema pallidum Lipoprotein Tp0768 Induces Proinflammatory Cytokines via TLR4/TLR9‐Mediated MAPK/NF‐κb Pathways in HMC3 Cells

International Journal of Microbiology, Volume 2026, Issue 1, 2026.
Neurogenic syphilis is a significant clinical feature of early and late syphilis infections. The disease process triggered by Treponema pallidum is closely related to the activation of the host’s inflammatory response. However, the exact molecular pathways of neuroinflammation caused by Treponema pallidum infection in the central nervous system remain ...
Binfeng Peng, Jirong Luo, Rong He, Jiajun Chen, Shilu Yan, Xiangping Zhou, Ting Cao, Yumeng Li, Xiaopeng Lan, Shuangquan Liu, Arif Jamal Siddiqui   +10 more
wiley   +1 more source