Results 41 to 50 of about 2,582 (167)

Contribution of 5-НТ1А and 5-НТ2А serotonin receptors into immunomodulation: Important role of psychoemotional condition

open access: yesБюллетень сибирской медицины, 2005
Experiments that were run on male mice of CBA line, immunized by sheep erythrocytes in dose 5 × 108 showed that 5-НТ1А selective agonist of serotonin receptors 8-OH-DPAT (1 mg/kg) causes suppression of immune response among aggressive animals and mice ...
S. M. Davydova
doaj   +1 more source

Neuro‐Immune Crosstalk: Molecular Mechanisms, Biological Functions, Diseases, and Therapeutic Targets

open access: yesMedComm, Volume 7, Issue 2, February 2026.
Neurons, immune cells, and other cellular components within the disease microenvironment (such as stromal cells and tumor cells) constitute a dynamically evolving ecosystem. Neurons directly modulate immune cell activity and inflammatory responses through the release of neurotransmitters (e.g., norepinephrine and CGRP), while also promoting tumor ...
Xin Guo   +11 more
wiley   +1 more source

Autonomic neuroimmunomodulation in chagasic cardiomyopathy [PDF]

open access: yesExperimental Physiology, 2012
Chagas disease is an endemic parasitic disease, caused by the flagellate protozoan Trypanosoma cruzi, with a high prevalence in Latin America. During its chronic phase, chronic chagasic cardiomyopathy is the most apparent clinical form, affecting 25–30% of patients.
Marcus Paulo, Ribeiro Machado   +1 more
openaire   +2 more sources

Astrocytic responses to binge ethanol in male and female mice: An examination of astrocytic glutamate transporters and density changes in the dorsal hippocampus

open access: yesAlcohol, Clinical and Experimental Research, Volume 50, Issue 1, January 2026.
The current work tested the hypothesis that sex differences in alcohol's effects are mediated by astrocytes. Using immunohistochemistry, qRT‐PCR, and ELISAs, we found that nondependent, binge‐like alcohol‐induced increases in hippocampal astrocyte density were more robust in females.
Candace Swepson   +6 more
wiley   +1 more source

Neuroimmunomodulation by estrogen in health and disease

open access: yesAIMS Neuroscience, 2020
Systemic homeostasis is maintained by the robust bidirectional regulation of the neuroendocrine-immune network by the active involvement of neural, endocrine and immune mediators. Throughout female reproductive life, gonadal hormones undergo cyclic variations and mediate concomitant modulations of the neuroendocrine-immune network. Dysregulation of the
Hannah P Priyanka, Rahul S Nair
openaire   +3 more sources

Neurotransmitters Modulate Intrathymic T-cell Development

open access: yesFrontiers in Cell and Developmental Biology, 2021
The existence of a crosstalk between the nervous and immune systems is well established. Neurotransmitters can be produced by immune cells, whereas cytokines can be secreted by cells of nervous tissues.
Carolina Francelin   +14 more
doaj   +1 more source

Neuroimmunomodulation in obesity

open access: yesInternational Journal of Clinical and Experimental Physiology, 2015
Obesity is the major risk factor for many chronic diseases such as diabetes, hypertension, cardiovascular diseases, and cancer. Obesity has a negative impact on the immune systems. Obesity is associated with chronic low-grade inflammation and altered immune functions. The regulation of body weight is by the interplay of many neuronal circuitries in the
GopalKrushna Pal   +3 more
openaire   +1 more source

Human umbilical cord mesenchymal stem cells promote peripheral nerve repair via paracrine mechanisms

open access: yesNeural Regeneration Research, 2015
Human umbilical cord-derived mesenchymal stem cells (hUCMSCs) represent a promising young-state stem cell source for cell-based therapy. hUCMSC transplantation into the transected sciatic nerve promotes axonal regeneration and functional recovery.
Zhi-yuan Guo   +4 more
doaj   +1 more source

Do vaccinations influence the development of Alzheimer disease?

open access: yesHuman Vaccines & Immunotherapeutics, 2023
A growing literature supports a protective association between vaccines targeting an array of pathogens (e.g., influenza, pneumococcus, herpes zoster) and the risk of Alzheimer disease (AD).
Avram S. Bukhbinder   +4 more
doaj   +1 more source

Treponema pallidum Lipoprotein Tp0768 Induces Proinflammatory Cytokines via TLR4/TLR9‐Mediated MAPK/NF‐κb Pathways in HMC3 Cells

open access: yesInternational Journal of Microbiology, Volume 2026, Issue 1, 2026.
Neurogenic syphilis is a significant clinical feature of early and late syphilis infections. The disease process triggered by Treponema pallidum is closely related to the activation of the host’s inflammatory response. However, the exact molecular pathways of neuroinflammation caused by Treponema pallidum infection in the central nervous system remain ...
Binfeng Peng   +10 more
wiley   +1 more source

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