Results 21 to 30 of about 2,582 (167)

Gestational Hypothyroxinemia Shifts Th1/Th17 Immunity and Innate Lymphoid Cell Balance in the Adult Offspring during the Presymptomatic Stage of Experimental Autoimmune Encephalomyelitis

open access: yesNeuroimmunomodulation
Introduction: Thyroid hormone homeostasis during pregnancy is crucial for proper neurodevelopment and cognitive capacity during adulthood. Accumulating evidence reveals that gestational hypothyroxinemia (HTX) modulates the immune response of ...
Sebastian Gatica   +12 more
doaj   +1 more source

The Sex-Specific Effects of Early Life Adversity and Chronic Psychosocial Stress during Adulthood on Bone Are Mitigated by Mycobacterium vaccae NCTC 11659 in Mice

open access: yesNeuroimmunomodulation
Introduction: Chronic stress is a major burden in our society and increases the risk for various somatic and mental diseases, in part via promoting chronic low-grade inflammation.
Dorothea Gebauer   +8 more
doaj   +1 more source

The Perinatal Microbiota-Gut-Brain Axis: Implications for Postpartum Depression

open access: yesNeuroimmunomodulation
Background: Pregnancy and childbirth are accompanied by widespread maternal physiological adaptations and hormonal shifts that have been suggested to result in a period of vulnerability for the development of mood disorders such as postpartum ...
Marie Armbruster, Paul Forsythe
doaj   +1 more source

Effects of Oral Administration of the Probiotic Lactobacillus rhamnosus GG on the Proteomic Profiles of Cerebrospinal Fluid and Immunoregulatory Signaling in the Hippocampus of Adult Male Rats

open access: yesNeuroimmunomodulation
Introduction: The microbiome-gut-brain axis, by modulating bidirectional immune, metabolic, and neural signaling pathways in the host, has emerged as a target for the prevention and treatment of psychiatric and neurological disorders.
Kelsey M. Loupy   +11 more
doaj   +1 more source

Inflammation: The Common Pathway of Stress-Related Diseases

open access: yesFrontiers in Human Neuroscience, 2017
While modernization has dramatically increased lifespan, it has also witnessed that the nature of stress has changed dramatically. Chronic stress result failures of homeostasis thus lead to various diseases such as atherosclerosis, non-alcoholic fatty ...
Yun-Zi Liu, Yun-Xia Wang, Chun-Lei Jiang
doaj   +1 more source

Age-Related Variation in Sympathetic Nerve Distribution in the Human Spleen

open access: yesFrontiers in Neuroscience, 2021
Introduction: The cholinergic anti-inflammatory pathway (CAIP) has been proposed as an efferent neural pathway dampening the systemic inflammatory response via the spleen.
Cindy G. J. Cleypool   +9 more
doaj   +1 more source

Psychedelics, entactogens and psychoplastogens for depression and related disorders

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 14, Page 3897-3919, July 2026.
Currently, the most actively investigated rapidly acting antidepressants, anxiolytics and/or anti PTSD agents, include psychedelics e.g. psilocybin, LSD, N,N‐dimethyltryptamine, ayahuasca; non‐hallucinogenic entactogens, e.g. MDMA; psychoplastogens which rapidly promote neuroplasticity, e.g.
Daniel Hoyer
wiley   +1 more source

Regular Positive Human Contacts Do Not Improve Pigs’ Response to a Lipopolysaccharide Immune Challenge

open access: yesNeuroimmunomodulation
Introduction: Little is known about the effects of a positive human-animal relationship on animal health and resilience. This study investigated the effects of regular positive human-animal interactions on pigs’ response to an immune challenge.
Oceane Schmitt   +5 more
doaj   +1 more source

Mismatch negativity, social cognition, and functional outcomes in patients after traumatic brain injury

open access: yesNeural Regeneration Research, 2015
Mismatch negativity is generated automatically, and is an early monitoring indicator of neuronal integrity impairment and functional abnormality in patients with brain injury, leading to decline of cognitive function.
Hui-yan Sun   +3 more
doaj   +1 more source

Neuroimmunomodulation in the Pathogenesis of Alzheimer’s Disease

open access: yesNeuroimmunomodulation, 2010
Evidence has been cumulated on the role of microglia cells deregulation and alterations in their interaction patterns with brain neurons, in the pathway towards neurodegeneration in Alzheimer’s disease (AD). After the failure of the amyloid hypothesis to explain AD pathogenesis, current hypotheses focus on tau self-polymerization into pathological ...
Morales, Inelia   +2 more
openaire   +6 more sources

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