Results 31 to 40 of about 9,739 (239)

Placental Alterations in Autism Spectrum Disorder: An In Silico Approach to circRNA-miRNA-mRNA Networks. [PDF]

Int J Dev Neurosci
The study identified circRNA–miRNA–mRNA interactions in ASD and placenta, finding 71 ASD‐linked circRNA and 30 highly expressed in the placenta. Five genes (SRSF11, PSMD11, NOTCH1, CREBBP, TBL1X) overlapped, with hsa‐MAN1A2_0008 showing a key regulatory potential, highlighting circRNA as possible mediators between ASD and placental alterations ...
Braz-Barbosa B, Gottfried C, Santos-Terra J.   +2 more
europepmc   +2 more sources

Role of Endocannabinoids on Neuroinflammation in Autism Spectrum Disorder Prevention [PDF]

Journal of Clinical and Diagnostic Research, 2017
Autism Spectrum Disorder (ASD) disease has become a mounting socio-economical alarm around the world. Neuroinflammtion had been shown in postmortem brain specimens from ASD patients.
Syed Shahid Habib, Khalid Al-Regaiey, Shahid Bashir, Muhammad Iqbal   +3 more
doaj   +1 more source

Chorioamnionitis disrupts erythropoietin and melatonin homeostasis through the placental-fetal-brain axis during critical developmental periods

Frontiers in Physiology, 2023
Introduction: Novel therapeutics are emerging to mitigate damage from perinatal brain injury (PBI). Few newborns with PBI suffer from a singular etiology. Most experience cumulative insults from prenatal inflammation, genetic and epigenetic vulnerability,
Yuma Kitase, Nethra K. Madurai, Sarah Hamimi, Ryan L. Hellinger, O. Angel Odukoya, Sindhu Ramachandra, Sankar Muthukumar, Vikram Vasan, Riley Sevensky, Shannon E. Kirk, Alexander Gall, Timothy Heck, Maide Ozen, Benjamin C. Orsburn, Shenandoah Robinson, Shenandoah Robinson, Lauren L. Jantzie, Lauren L. Jantzie, Lauren L. Jantzie, Lauren L. Jantzie   +19 more
doaj   +1 more source

Interleukin-6 gene (IL-6): a possible role in brain morphology in the healthy adult brain [PDF]

, 2012
Background: Cytokines such as interleukin 6 (IL-6) have been implicated in dual functions in neuropsychiatric disorders. Little is known about the genetic predisposition to neurodegenerative and neuroproliferative properties of cytokine genes.
A Kitamura, AA Willette, AH Miller, AL Jefferson, AL Marsland, AL Sousa, American Psychiatric Association, Astrid V Rauch, AT Beck, B Balasubramaniam, B Viviani, Bernhard T Baune, BL Pierce, BT Baune, BT Baune, Carsten Konrad, CF Terry, Christina Uhlmann, CS Carlson, Dominik Grotegerd, E Brietzke, E Halperin, E Vermetten, Eva Birosova, F Faul, GM MacQueen, H Tilg, H-U Wittchen, Harald Kugel, I HapMap, I Hickie, I Morales, J Ashburner, J Hannestad, J McAfoose, J Oh, JA Wagner, JE Malberg, JM Gatt, JM Kim, Jochen Bauer, JP Godbout, K Kasai, K Pham, Katharina Domschke, KK Bowen, L Capuron, L Christiansen, L Vallieres, L Vitkovic, LD Ward, M Bonafe, M Murphy, M Pickering, M Yamada, MA Kahn, MA Munoz-Fernandez, MK Kang, ML Monje, MT Heneka, N Ohbayashi, N Pervaiz, N Raz, N Tzourio-Mazoyer, O Davidovich, O Islam, P Angelopoulos, P Oeth, P Videbech, Patricia Ohrmann, RA Gadient, RA Gadient, RM Thomas, S Campbell, S Eickhoff, S Ihara, S Ihara, S Lehrl, S Matsuda, S Toulmond, SA Loddick, SD Forman, Sonja Schöning, T Beblo, T Frodl, T Hama, T Hama, T Hirano, Thomas Suslow, U Dannlowski, Udo Dannlowski, V Tancredi, Volker Arolt, Walter Heindel, Y Akaneya, Y Dowlati, Y Kushima, Y Kushima, YP Peng, YY Wu   +99 more
core   +3 more sources

Microbial lysate upregulates host oxytocin [PDF]

, 2017
Neuropeptide hormone oxytocin has roles in social bonding, energy metabolism, and wound healing contributing to good physical, mental and social health. It was previously shown that feeding of a human commensal microbe Lactobacillus reuteri (L.
Alm, Eric J., Cheung, Harry K., DiBenedictis, Brett T., Didyk, Eliska, Erdman, Susan E., Hardas, Alexandros, Ibrahim, Yassin, Kolandaivelu, Kumaran, Levkovich, Tatiana, Poutahidis, Theofilos, Ricciardi, Catherine E., Shikhman, Lana, Varian, Bernard J., Veenema, Alexa H.   +13 more
core   +1 more source

Neuroimmunomodulation induced by mud-bath therapy: clinical benefits and bioregulation of the innate/inflammatory responses induced by a peloid enriched with rosmarinic acid in elderly patients with osteoarthritis. [PDF]

Int J Biometeorol
Ortega-Collazos E, Otero E, López-Jurado C, Navarro C, Martín-Cordero L, Gálvez I, Torres-Piles S, Ortega E, Hinchado MD.   +8 more
europepmc   +3 more sources

Aire and Foxp3 expression in a particular microenvironment for T-cell differentiation [PDF]

, 2009
peer ...
Dorban, Gauthier, Geenen, Vincent, Hansenne, Isabelle, Louis, Céline, Martens, Henri, Peterson, Part, Renard, Chantal   +6 more
core   +1 more source

Exercise promotes motor functional recovery in rats with corticospinal tract injury: anti-apoptosis mechanism

Neural Regeneration Research, 2015
Studies have shown that exercise interventions can improve functional recovery after spinal cord injury, but the mechanism of action remains unclear. To investigate the mechanism, we established a unilateral corticospinal tract injury model in rats by ...
Ting-ting Hou, Xiao-yu Yang, Peng Xia, Su Pan, Jian Liu, Zhi-ping Qi   +5 more
doaj   +1 more source

Catecholamine stress alters neutrophil trafficking and impairs wound healing by β2-adrenergic receptor-mediated upregulation of IL-6. [PDF]

, 2014
Stress-induced hormones can alter the inflammatory response to tissue injury; however, the precise mechanism by which epinephrine influences inflammatory response and wound healing is not well defined.
Byrne, Barbara A, Gorouhi, Farzam, Granick, Jennifer L, Isseroff, Rivkah R, Kim, Min-Ho, Ramirez, Sandra, Simon, Scott I, Soulika, Athena M   +7 more
core   +2 more sources

Gestational Hypothyroxinemia Shifts Th1/Th17 Immunity and Innate Lymphoid Cell Balance in the Adult Offspring during the Presymptomatic Stage of Experimental Autoimmune Encephalomyelitis

Neuroimmunomodulation
Introduction: Thyroid hormone homeostasis during pregnancy is crucial for proper neurodevelopment and cognitive capacity during adulthood. Accumulating evidence reveals that gestational hypothyroxinemia (HTX) modulates the immune response of ...
Sebastian Gatica, Nicolas Paillal, Ma. Andreina Rangel-Ramírez, Luis Méndez, Alonso Fernández-Tello, Alexis M. Kalergis, Susan M. Bueno, Pablo A. González, Jorge A. Soto, Felipe Simon, Leandro J. Carreño, Felipe Melo-Gonzalez, Claudia A. Riedel   +12 more
doaj   +1 more source