Autonomic neuroimmunomodulation in chagasic cardiomyopathy [PDF]
Experimental Physiology, 2012 Chagas disease is an endemic parasitic disease, caused by the flagellate protozoan Trypanosoma cruzi, with a high prevalence in Latin America. During its chronic phase, chronic chagasic cardiomyopathy is the most apparent clinical form, affecting 25–30% of patients.
Marcus Paulo, Ribeiro Machado +1 more
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Navigating the Neuroimmunomodulation Frontier: Pioneering Approaches and Promising Horizons—A Comprehensive Review [PDF]
International Journal of Molecular SciencesLara Baticic Pucar
exaly +4 more sources
Acupuncture's Multisystem Neuroimmunomodulation: Central-Peripheral Interactions in Gastroenteric, Psychiatric, and Chronic Pain Disorders. [PDF]
CNS Neurosci TherThis work elucidates acupuncture's multisystem therapeutic mechanisms through central‐peripheral crosstalk. Using functional gastrointestinal disorders, psychiatric disorders, and chronic pain models, we demonstrate its efficacy in rebalancing gut‐brain signaling, neuroimmune‐endocrine integration, and humoral network modulation.
Zhang L +6 more
europepmc +4 more sources
Neuroimmunomodulation in obesity
International Journal of Clinical and Experimental Physiology, 2015 Obesity is the major risk factor for many chronic diseases such as diabetes, hypertension, cardiovascular diseases, and cancer. Obesity has a negative impact on the immune systems. Obesity is associated with chronic low-grade inflammation and altered immune functions. The regulation of body weight is by the interplay of many neuronal circuitries in the
GopalKrushna Pal +3 more
openaire +2 more sources
NeuroprotectionParkinson's disease (PD) is a chronic, progressive neurodegenerative disorder. No disease‐modifying therapies exist. This review proposes that PD susceptibility begins with epigenetic changes and neuroimmune activity—factors that alter gene expression ...
Ayodeji Johnson Ajibare +2 more
doaj +2 more sources
Navigating the Ethereal Tightrope: The Nanogenerator Manipulates Neurons for Immune Equilibrium
Advanced ScienceThe intricacies of neuroimmunity underscore its pivotal role in the onset and progression of neurological diseases, yet its precise modulation remains a formidable challenge.
Jia Du +5 more
doaj +2 more sources
Indian Journal of Rheumatology, 2020 Progressive clinical research in the field of neuroimmunomodulation has formed a base for the development of a new therapeutic paradigm for various inflammatory diseases, including rheumatoid arthritis (RA).
Prasan Deep Rath +2 more
doaj +2 more sources
Innate Immune Tolerance Regulates Microglia Response to Aβ Oligomers. [PDF]
J NeurochemMicroglia are the primary innate immune cells residing in the brain parenchyma, and their activation in Alzheimer's disease (AD) results in increased neuroinflammation. The development of innate immune memory in response to various stimuli is a crucial mechanism that allows microglia to tailor their responses to future inflammatory challenges.
Valerio RR +9 more
europepmc +2 more sources
Molecular Mechanisms Driving Precision Medicine in Perioperative Care: Integrating Inflammation, Metabolism, and Neuroimmunomodulation for Personalized Outcomes. [PDF]
Int J Mol SciWenner AK, Andereggen L, Luedi MM.
europepmc +4 more sources
Fluoxetine reduces murine graft-versus-host disease by induction of T cell immunosuppression [PDF]
, 2013 Serotonin reuptake inhibitors (SRIs) are widely used drugs in the treatment of depression and anxiety disorders. Although SRIs are generally regarded as safe drugs with relatively few side effects, literature suggests that high concentrations of SRIs may
Billiau, An D +6 more
core +6 more sources