Results 11 to 20 of about 2,582 (167)

KETO-MOOD: Ketogenic Diet for Microbiome Optimization and Overcoming Depression – A Protocol for a Randomized Controlled Trial

Neuroimmunomodulation
Introduction: Major depressive disorder (MDD) significantly impacts millions worldwide, with limited success in achieving remission for many patients, leading to high disease burden and increased suicide risk. Psychotherapy and antidepressants,
Katarzyna Hongler, Astrid Lounici, Erin Maurer, Ueli Lanz, Orsolya Szathmari, Yvonne Reuter, Sandra Nussbaum, Ines Steinborn, Annika Haedrich, Melina A. Mölling, Ulf Wein, Iona Bocek, Luca Hersberger, Annette B. Brühl, Undine E. Lang, Timur Liwinski   +15 more
doaj   +2 more sources

Focused Ultrasound-Mediated Blood–Brain Barrier Opening Best Promotes Neuroimmunomodulation through Brain Macrophage Redistribution

Neuroglia, 2023
Neuroimmunomodulation is a promising form of drug-free treatment for neurological diseases ranging from Alzheimer’s disease to depression. The evidence supporting the efficacy of focused ultrasound (FUS) neuroimmunomodulation is encouraging; however, the
Alina R. Kline-Schoder, Rebecca L. Noel, Hemali Phatnani, Vilas Menon, Elisa E. Konofagou   +4 more
doaj   +1 more source

Prefrontally modulated vagal neuroimmunomodulation is associated with telomere length

Frontiers in Neuroscience, 2022
BackgroundAccumulated senescent cells are proposed to be one of the main drivers of age-related pathology such as dementia and cancer through disruption of tissue structure and function. We recently proposed the Neuro-Immuno-Senescence Integrative Model (
Torvald F. Ask, Torvald F. Ask, Stefan Sütterlin, Stefan Sütterlin   +3 more
doaj   +1 more source

Revisiting the neuroinflammation hypothesis in Alzheimer’s disease: a focus on the druggability of current targets

Frontiers in Pharmacology, 2023
Alzheimer’s disease (AD) is the most common form of neurodegenerative disease and disability in the elderly; it is estimated to account for 60%–70% of all cases of dementia worldwide.
Maylin Wong-Guerra, Maylin Wong-Guerra, Maylin Wong-Guerra, Camila Calfio, Camila Calfio, Ricardo B. Maccioni, Ricardo B. Maccioni, Leonel E. Rojo, Leonel E. Rojo, Leonel E. Rojo   +9 more
doaj   +1 more source

Stroke in SARS-CoV-2 Infection: A Pictorial Overview of the Pathoetiology

Frontiers in Cardiovascular Medicine, 2021
Since the early days of the pandemic, there have been several reports of cerebrovascular complications during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.
Saeideh Aghayari Sheikh Neshin, Shima Shahjouei, Eric Koza, Isabel Friedenberg, Faezeh Khodadadi, Mirna Sabra, Firas Kobeissy, Saeed Ansari, Georgios Tsivgoulis, Jiang Li, Vida Abedi, Vida Abedi, Donna M. Wolk, Ramin Zand   +13 more
doaj   +1 more source

In Vitro Effects of Cannabidiol on Activated Immune–Inflammatory Pathways in Major Depressive Patients and Healthy Controls

Pharmaceuticals, 2022
Major depressive disorder and major depressive episodes (MDD/MDE) are characterized by the activation of the immune–inflammatory response system (IRS) and the compensatory immune–regulatory system (CIRS).
Muanpetch Rachayon, Ketsupar Jirakran, Pimpayao Sodsai, Siriwan Klinchanhom, Atapol Sughondhabirom, Kitiporn Plaimas, Apichat Suratanee, Michael Maes   +7 more
doaj   +1 more source

The Immune Profile of Major Dysmood Disorder: Proof of Concept and Mechanism Using the Precision Nomothetic Psychiatry Approach

Cells, 2022
Major depressive disorder and a major depressive episode (MDD/MDE) are characterized by activation of the immune-inflammatory response system (IRS) and the compensatory immune-regulatory system (CIRS).
Michael Maes, Muanpetch Rachayon, Ketsupar Jirakran, Pimpayao Sodsai, Siriwan Klinchanhom, Piotr Gałecki, Atapol Sughondhabirom, Agnieszka Basta-Kaim   +7 more
doaj   +1 more source

An Introduction to Neuroimmunomodulation and Aging [PDF]

Neuroimmunomodulation, 2008
gerontologists. Accordingly, this special issue of Neuroimmunomodulation provides an opportunity to review progress in this field of research. An introductory article presented by De la Fuente reviews the most widely accepted theories of aging, especially the oxidation-inflammation theory, and how the neuroimmune communication is impaired with age ...
Moisés Evandro, Bauer, Mónica, De la Fuente   +1 more
openaire   +2 more sources

Decrease of IL-1β and TNF in the Spinal Cord Mediates Analgesia Produced by Ankle Joint Mobilization in Complete Freund Adjuvant-Induced Inflammation Mice Model

Frontiers in Physiology, 2022
ObjectiveThis study aims to investigate the effects of ankle joint mobilization (AJM) on mechanical hyperalgesia and peripheral and central inflammatory biomarkers after intraplantar (i.pl.) Complete Freund’s Adjuvant (CFA)-induced inflammation ...
Carlos Minoru Omura, Daniela Dero Lüdtke, Daniela Dero Lüdtke, Verônica Vargas Horewicz, Paula Franson Fernandes, Taynah de Oliveira Galassi, Afonso Shiguemi Inoue Salgado, Juliete Palandi, Juliete Palandi, Heloiza dos Santos Baldança, Heloiza dos Santos Baldança, Edsel B. Bittencourt, Josiel Mileno Mack, Josiel Mileno Mack, Josiel Mileno Mack, Lynsey A. Seim, Daniel Fernandes Martins, Franciane Bobinski   +17 more
doaj   +1 more source

Exercise promotes motor functional recovery in rats with corticospinal tract injury: anti-apoptosis mechanism

Neural Regeneration Research, 2015
Studies have shown that exercise interventions can improve functional recovery after spinal cord injury, but the mechanism of action remains unclear. To investigate the mechanism, we established a unilateral corticospinal tract injury model in rats by ...
Ting-ting Hou, Xiao-yu Yang, Peng Xia, Su Pan, Jian Liu, Zhi-ping Qi   +5 more
doaj   +1 more source